Role of surgery and radiation therapy in the management of gestational trophoblastic disease

Bailliere's Best Practice and Research in Clinical Obstetrics and Gynaecology

Volumn 17, Issue 6, 2003, Pages 943-957

  Soper, Johm T ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gestational trophoblastic disease, embolization; Gestational trophoblastic disease, hysterectomy; Gestational trophoblastic disease, radiation therapy; Gestational trophoblastic disease, surgery; Gestational trophoblastic disease, thoracotomy; Hydatidiform mole, dilatation and curettage; Hydatidiform mole, evacuation; Hydatidiform mole, hysterectomy; Placental site trophoblastic tumour, hysterectomy; Placental site trophoblastic tumour, surgery

Indexed keywords

ANTINEOPLASTIC AGENT; CHORIONIC GONADOTROPIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; ETOPOSIDE; METHOTREXATE; OXYTOCIN; PROSTAGLANDIN DERIVATIVE;

ARTIFICIAL EMBOLISM; BLOOD TOXICITY; BRAIN METASTASIS; CANCER CHEMOTHERAPY; CANCER SURVIVAL; CHORIOCARCINOMA; CURETTAGE; DRUG MEGADOSE; FEMALE; GYNECOLOGICAL RADIOGRAPHY; HUMAN; HYDATIDIFORM MOLE; HYSTERECTOMY; LABOR INDUCTION; LIVER METASTASIS; LUNG METASTASIS; MALIGNANT TRANSFORMATION; METASTASIS; MYOMETRIUM; PATIENT MONITORING; PELVIS CANCER; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SALVAGE THERAPY; SURGICAL EQUIPMENT; THORACOSCOPY; TROPHOBLASTIC DISEASE; TROPHOBLASTIC TUMOR; UTERUS SURGERY; VAGINA BLEEDING;

EID: 0347653541     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1521-6934(03)00091-9     Document Type: Review

References (82)

1. Schlaerth JB, Morrow CP, Montz FJ & D'Ablaing G. Initial management of hydatidiform mole. Obstetrics and Gynecology 1988; 158: 1299-1306.
2. Flam F, Lundstrom V & Pettersson F. Medical induction prior to surgical evacuation of hydatidiform mole: Is there a greater risk of persistent trophoblastic disease. European Journal of Obstetrics, Gynecology and Reproductive Biology 1991; 42: 57-60.
3. Tidy JA, Gillespi AM, Bright N et al. Gestational trophoblastic disease: A study of mode of evacuation and subsequent need for treatment with chemotherapy. Gynecologic Oncology 2000; 78: 309-312.
4. Tow WSH. The place of hysterotomy in the treatment of hydatidiform mole. Australian and New Zealand Journal of Obstetrics and Gynaecology 1967; 7: 97-98.
5. Curry SL, Hammond CB, Tyrey H et al. Hydatidiform mole. Diagnosis, management and long-term follow-up of 347 patients. Obstetrics and Gynecology 1975; 45: 1-8.
6. Soper JT. Surgical therapy for gestational trophoblastic disease. Journal of Reproductive Medicine 1994; 39: 168-174.
7. Rice LW, Genest DR, Berkowitz RS et al. Pathologic features of sharp curettings in complete hydatidiform mole. Predictors of persistent gestational trophoblastic disease. Journal of Reproductive Medicine 1991; 36: 17-20.
8. Soto-Wright V, Bernstein M, Goldstein DP & Berkowitz RS. The changing clinical presentation of complete hydatidiform mole. Obstetrics and Gynecology 1995; 86: 775-779.
9. Coukos G, Makrigiannakis A, Chung J et al. Complete hydatidiform mole. A disease with a changing profile. Journal of Reproductive Medicine 1999; 44: 698-704.
10. Gemar O, Segel S, Kopmar A & Sasson E. The current clinical presentation of complete molar pregnancy. Archives of Gynecology and Obstetrics 2000; 264: 33-34.
11. Sebire NJ, Rees H, Paradinas F et al. The diagnostic implications of routine ultrasound examination in histologically confirmed early molar pregnancies. Ultrasound in Obstetrics and Gynecology 2001; 18: 662-665.
12. Twiggs LB, Morrow DP & Schlaerth JB. Acute pulmonary complications of hydatidiform mole. American Journal of Obstetrics and Gynecology 1979; 135: 189-194.
13. Cohle SD & Petty CS. Sudden death caused by embolization of trophoblast from hydatidiform mole. Journal of Forensic Science 1985; 30: 1279-1283.
14. Kohorn EI. Clinical management and neoplastic sequelae of trophoblastic embolization associated with hydatidiform mole. Obstetrical and Gynecological Survey 1987; 42: 484-488.
15. Garner EI, Chang-Lee WY, Lu KH et al. Trophoblastic pulmonary embolization after hysterectomy for invasive complete mole. A case report. Journal of Reproductive Medicine 1999; 44: 908-912.
16. Rosen T, Sutin K, Carreno CA et al. Central hemodynamic monitoring in a woman with acute respiratory insufficiency after evacuation of a complete molar pregnancy. A case report. Journal of Reproductive Medicine 2001; 46: 916-922.
17. Cotton DB, Bernstein SG, Reed JA et al. Hemodynamic observations in evacuation of molar pregnancy. American Journal of Obstetrics and Gynecology 1980; 138: 6-10.
18. Bandy LC, Clarke-Pearson DL & Hammond CB. Malignant potential of gestational trophoblastic disease at the extremes of reproductive life. Obstetrics and Gynecology 1984; 64: 395-399.
19. Tsukamoto N, Iwasaka T, Kashimura Y et al. Gestational trophoblastic disease in women aged 50 or more. Gynecological Oncology 1985; 20: 53-61.
20. Bahar AM, El-Ashnuehi MS & Senthilseve A. Hydatidiform mole in the elderly: Hysterectomy or evacuation? International Journal of Gynaecology and Obstetrics 1989; 29: 233-238.
21. Montz FJ, Schlaerth JB & Morrow CP. The natural history of theca lutein cysts. Obstetrics and Gynecology 1988; 72: 233-238.
22. Brewer JI, Smith RT & Pratt GB. Choriocarcinoma: Absolute survival rates of 122 patients treated by hysterectomy. American Journal of Obstetrics and Gynecology 1963; 85: 841-843.
23. Hammond CB, Weed Jr. JC & Currie JL. The role of operation in the current therapy of gestational trophoblastic disease. American Journal or Obstetrics and Gynecology 1980; 136: 844-858.
24. Lao TT, Lee FH & Yeung SS. Repeat curettage after evacuation of hydatidiform mole: An appraisal. Acta Obstetricia et Gynecologica Scandinavica 1987; 65: 305-307.
25. Flam F & Lundstrom V. The value of endometrial curettage in the follow-up of hydatidiform mole. Acta Obstetricia et Gynecologica Scandinavica 1988; 67: 649-651.
26. Schlaerth JB, Morrow DP & Rodriguez M. Diagnostic and therapeutic curettage in gestational trophoblastic disease. American Journal of Obstetrics and Gynecology 1990; 162: 1465-1470.
27. Berkowitz RS, Goldstein DP, Driscoll SG et al. Pretreatment curettage: A predictor of chemotherapy response in gestational trophoblastic neoplasia. Gynecological Oncology 1980; 10: 39-43.
28. Suzuka K, Matsui H, Iitsuka Y et al. Adjuvant hysterectomy in low-risk gestational trophoblastic disease. Obstetrics and Gynecology 2001; 97: 431-434.
29. DuBeshter B, Berkowitz R, Goldstein DP et al. Metastatic gestational trophoblastic disease: Experience at the New England Trophoblastic Disease Center, 1965 to 1985. Obstetrics and Gynecology 1987; 69: 390-395.
30. Roberts JP & Lurain JR. Treatment of low-risk gestational trophoblastic tumours with single-agent chemotherapy. American Journal of Obstetrics and Gynecology 1996; 174: 1917-1923.
31. Ilancheran A & Ratnam SS. The role of surgery in the treatment of trophoblastic disease. International Journal of Gynaecology and Obstetrics 1980; 18: 237-239.
32. Bolis G, Belloni C, Vergadoro F et al. The role of surgery in gestational trophoblastic disease. Tumori 1983; 69: 553-557.
33. Lehman E, Gershenson DM, Burke TW et al. Salvage surgery for chemoresistant gestational trophoblastic disease. Journal of Clinical Oncology 1994; 12: 2737-2742.
34. Pisal N, North C, Tidy J & Hancock B. Role of hysterectomy in management of gestational trophoblastic disease. Gynecologic Oncology 2002; 87: 190-192.
35. Mutch DG, Soper JT, Babcock CJ et al. Recurrent gestational trophoblastic disease: Experience of the Southeastern Regional Trophoblastic Disease Center. Cancer 1990; 66: 978-982.
36. Chang YL, Chang TC, Hsueh S et al. Prognostic factors and treatment for placental site trophoblastic tumour- report of 3 cases and analysis of 88 cases. Gynecologic Oncology 1999; 73: 216-222.
37. Gillespie AM, Liyim D, Goepel JR et al. Placental site trophoblastic tumours: A rare but potentially curable cancer. British Journal of Cancer 2000; 82: 118-1190.
38. Feltmate CM, Genest DR, Wise L et al. Placental site trophoblastic tumor: A 17-year experience at the New England Trophoblastic Disease Center. Gynecologic Oncology 2001; 82: 415-419.
39. Papadopoulos AJ, Foskett M, Seckel MJ et al. Twenty-five years' clinical experience with placental site trophoblastic tumors. Journal of Reproductive Medicine 2002; 47: 460-464.
40. Berkowitz BJ, Jones JG, Merkatz IR & Runowicz CD. Ovarian conservation in placental site trophoblastic tumor. Gynecologic Oncology 1990; 37: 239-243.
41. Lang JF, Childers JN & Surwit EA. Laparoscopic hysterectomy for persistent gestational trophoblastic neoplasia. Journal of the American Association of Gynecologic Laparoscopists 1995; 2: 475-477.
42. Wilson RB, Beechman CT & Symmonds RE. Conservative surgical management of chorioadenoma destruens. Obstetrics and Gynecology 1965; 26: 814-820.
43. Kanazawa K, Sasagawa M, Suzuki T & Takeuchi S. Clinical evaluation of focal excision of myometrial lesion for treatment of invasive hydatidiform mole. Acta Obstetricia et Gynecologica Scandinavica 1988; 67: 487-492.
44. Leiserowitz GS & Webb MJ. Treatment of placental site trophoblast tumor with hysterotomy and uterine reconstruction. Obstetrics and Gynecology 1996; 88: 696-699.
45. Case AM, Wilson S, Colgan TJ & Greenblatt EM. Fertility-sparing surgery, with subsequent pregnancy in persistent gestational trophoblastic neoplasia: A case report. Human Reproduction 2001; 16: 360-364.
46. Tsuji Y, Tsubamoto H, Hori M et al. Case of PSTT treated with chemotherapy followed by open uterine tumor resection to preserve fertility. Gynecologic Oncology 2002; 87: 303-307.
47. Shirley RL, Goldstein DP & Collins Jr. JJ. The role of thoracotomy in the management of patients with chest metastases from gestational trophoblastic disease. Journal of Thoracic and Cardiovascular Surgery 1972; 63: 545-550.
48. Edwards JL, Makey AR & Bagshawe KD. The role of thoracotomy in the management of pulmonary metastases of gestational choriocarcinoma. Clinical Oncology 1975; 1: 329-339.
49. Sink JD, Hammond CB & Young WG. Pulmonary resection in the management of metastases from choriocarcinoma. Journal of Thoracic and Cardiovascular Surgery 1981; 81: 830-834.
50. Wong LC & Ma HK. Persistent chest opacity in trophoblastic disease: Is thoracotomy justified? Australian and New Zealand Journal of Obstetrics and Gynaecology 1983; 23: 237-240.
51. Lifshitz H, Barber CE & Hammond CB. The pulmonary metastases of choriocarcinoma. Obstetrics and Gynecology 1977; 49: 412-416.
52. Jones WB, Romain K, Erlandson RA et al. Thoracotomy in the management of gestational choriocarcinoma. A clinicopathological study. Cancer 1993; 72: 2175-2181.
53. Suzuki T, Kitami A, Hori G et al. Metastatic choriocarcinoma resected nine years after hydatidiform mole. Scandinavian Cardiovascular Journal 1999; 33: 180-182.
54. Tidy JA, Rustin GJ, Newlands ES et al. Presentation and management of choriocarcinoma after nonmolar pregnancy. British Journal of Obstetrics and Gynaecology 1995; 102: 715-719.
55. Tomoda Y, Arii Y, Kaseki S et al. Surgical indications for resection in pulmonary metastases of choriocarcinoma. Cancer 1980; 46: 2723-2730.
56. Xu LT, Suu CF, Wong YE et al. Resection of pulmonary metastatic choriocarcinoma in 43 drug-resistant patients. Annals of Thoracic Surgery 1985; 39: 257-259.
57. Lurain JR, Brewer JI, Mazur MT & Torok EE. Fatal gestational trophoblastic disease: An analysis of treatment failures. American Journal of Obstetrics and Gynecology 1982; 144: 391-395.
58. Evans Jr. AC, Soper JT, Clarke-Pearson DL et al. Gestational trophoblastic disease metastatic to the central nervous system. Gynecologic Oncology 1995; 59: 226-230.
59. Rustin GJ, Newlands ES, Begent RH et al. Weekly alternating etoposide, methotrexate and actinomycin/vincristine and cyclophosphamide chemotherapy for the treatment of CNS metastases of choriocarcinoma. Journal of Clinical Oncology 1989; 7: 900-903.
60. Ishizuka T, Tomoda Y, Kaseki S et al. Intracranial metastases of choriocarcinoma: A clinicopathologic study. Cancer 1983; 52: 1896-1903.
61. Kobayashi T, Kida Y, Yoshida J et al. Brain metastases of choriocarcinoma. Surgical Neurology 1982; 17: 395-403.
62. Janni W, Hantschmann P, Rehblock J et al. Successful treatment of malignant placental trophoblastic tumor with combined cytostatic-surgical approach: Case report and review of literature. Gynecologic Oncology 1999; 75: 164-169.
63. Goldberg GL, Yon DA, Bloch B & Levin W. Gestational trophoblastic disease: The significance of vaginal metastases. Gynecologic Oncology 1986; 24: 155-161.
64. Vadar MA, Altintas A & Demir SL. Gestational trophoblastic disease: The significance of vaginal metastases. European Journal of Gynaecological Oncology 2000; 21: 184-186.
65. Yinga S, Yang X, Sinyu Y & Hongzhao S. Clinical characteristics and treatment of gestational trophoblastic tumor with vaginal metastasis. Gynecologic Oncology 2002; 84: 416-419.
66. Soper JT, Mutch DG, Chin N et al. Renal metastases of gestational trophoblastic disease: A report of eight cases. Obstetrics and Gynecology 1988; 72: 796-798.
67. Dehaeck CM. Transcatheter embolization of pelvic vessels to stop intractable hemorrhage. Gynecologic Oncology 1986; 24: 9-16.
68. Pearl ML & Barga CA. Percutaneous transcatheter embolization for control of life-threatening pelvic hemorrhage from gestational trophoblastic disease. Obstetrics and Gynecology 1992; 80: 571-574.
69. Grumbine FC, Rosenschein NB, Brewerton MD et al. Management of liver metastases from gestational trophoblastic neoplasia. American Journal of Obstetrics and Gynecology 1980; 137: 959-961.
70. Heaton GE, Matthews TH & Christopherson WH. Malignant trophoblastic tumor with massive hemorrhage presenting as liver primary. A report of two cases. American Journal of Surgical Pathology 1986; 10: 342-347.
71. Lang EK. Reduced systemic toxicity from superselective chemoembolization compared to systemic chemotherapy in patients with high-risk metastatic gestational trophoblastic disease. Cardiovascular and Interventional Radiology 1997; 20: 280-284.
72. Maroulis GB, Hammon CB, Johnsrude IS et al. Arteriography and infusional chemotherapy in localized trophoblastic disease. Obstetrics and Gynecology 1975; 45: 397-406.
73. Lim AK, Agarwal R, Seckl MJ et al. Embolization of bleeding residual uterine vascular malformations in patients with treated gestational trophoblastic tumors. Radiology 2002; 222: 640-644.
74. Garner EI, Meyerovitz M, Goldstein DP & Berkowitz R. Successful term pregnancy after selective arterial embolization of symptomatic arteriovenous malformation in the setting of gestational trophoblastic tumor. Gynecologic Oncology 2003; 88: 69-72.
75. Brace KC. The role of irradiation in the treatment of metastatic trophoblastic disease. Radiology 1968; 91: 540-544.
76. Weed Jr JC & Hammond CB. Cerebral metastatic choriocarcinoma: Intensive therapy and prognosis. Obstetrics and Gynecology 1980; 55: 89-94.
77. Yordan Jr EL, Schlaerth J, Gaddis O & Morrow CP. Radiation therapy in the management of gestational choriocarcinoma metastatic to the central nervous system. Obstetrics and Gynecology 1987; 69: 627-630.
78. Small Jr W, Lurain JR, Shelty RM et al. Gestational trophoblastic disease metastatic to the brain. Radiology 1996; 200: 277-280.
79. Schecter NR, Mychalczak B, Jones W & Spriggs D. Prognosis of patients treated with whole-brain radiation therapy for metastatic gestational trophoblastic disease. Gynecologic Oncology 1998; 68: 183-192.
80. Barnard DE, Woodward KT, Yancy SG et al. Hepatic metastases of choriocarcinoma: A report of 15 patients. Gynecologic Oncology 1986; 25: 73-83.
81. Bakri YN, Subhi J, Amer M et al. Liver metastases of gestational trophoblastic tumor. Gynecologic Oncology 1993; 48: 110-113.
82. Crawford RA, Newlands E, Rustin GJ et al. Gestational trophoblastic disease with liver metastases: The Charing Cross experience. British Journal of Obstetrics and Gynaecology 1997; 104: 105-109.