Physical origin of peak tailing on C18-bonded silica in reversed-phase liquid chromatography

Journal of Chromatography A

Volumn 1028, Issue 1, 2004, Pages 75-88

  Gritti, Fabrice ^a,b   Guiochon, Georges ^a,b  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

Adsorption equilibrium; Affinity energy distribution; Caffeine; Column heterogeneity; Frontal analysis; Overloaded band profiles; Peak tailing; Phenol; Silanol activity; Silica

Indexed keywords

ADSORPTION; ADSORPTION ISOTHERMS; HYDROGEN BONDS; LIQUID CHROMATOGRAPHY; MATHEMATICAL MODELS; METHANOL; SATURATION (MATERIALS COMPOSITION); SILICA; SYNTHESIS (CHEMICAL);

ENERGY DISTRIBUTIONS;

AROMATIC COMPOUNDS;

CAFFEINE; CARBON; GLASS; METAL; METHANOL; METHYLSILANE; PHENOL; SILANE DERIVATIVE; SILICON DIOXIDE; UNCLASSIFIED DRUG; WATER;

ACIDITY; ADSORPTION; ARTICLE; DENSITY; ENERGY; HYBRID; HYDROGEN BOND; ISOLATION PROCEDURE; ISOTHERM; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MOLECULAR INTERACTION; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY;

EID: 0347635341     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2003.11.090     Document Type: Article

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