Use of floating electrodes in transient isotachophoresis to increase the sensitivity of detection

Lab on a Chip - Miniaturisation for Chemistry and Biology

Volumn 3, Issue 2, 2003, Pages 86-92

  Kurnik, Ronald T ^a   Boone, Travis D ^a   Nguyen, Uyen ^a   Ricco, Antonio J ^a   Williams, Steven J ^a  

^a ACLARA BioSciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISPERSION; ELECTRIC POTENTIAL; ELECTROPHORESIS; ISOTACHOPHORESIS; MICROELECTRODE; PRIORITY JOURNAL; SIGNAL DETECTION; COMPARATIVE STUDY; COMPUTER SIMULATION; DIFFUSION; ELECTROCHEMISTRY; ELECTRODE; INSTRUMENTATION; METHODOLOGY; MICROFLUIDICS; SENSITIVITY AND SPECIFICITY;

FLUORESCEIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE C SRC; PROTEIN-TYROSINE KINASE C-SRC;

COMPUTER SIMULATION; DIFFUSION; ELECTROCHEMISTRY; ELECTRODES; ELECTROPHORESIS; FLUORESCEIN; MICROFLUIDICS; PROTEIN-TYROSINE KINASES; SENSITIVITY AND SPECIFICITY;

EID: 0347631757     PISSN: 14730197     EISSN: 14730189     Source Type: Journal    
DOI: 10.1039/b212729f     Document Type: Article

References (37)

1. J. M. Ramsey and A. v. d. Berg, Micro Total Analysis Systems, Kluwer Academic Publishers, Dordrecht, 2001.
2. A. Manz, N. Graber and H. M. Widmer, Sens. Actuators, 1988, 14, 101.
3. A. Manz, D. J. Harrison, E. M. J. Verpoorte, J. C. Fettinger, A. Paulus, H. Ludi and H. M. Widmer, J. Chromatogr., 1992, 593, 253.
4. V. Dolnik, S. Liu and S. Jovanovich, Electrophoresis, 2000, 21, 41.
5. G. J. M. Bruin, Electrophoresis, 2000, 21, 3931.
6. A. Ramseier, F. v. Heeren and W. Thormann, Electrophoresis, 1998, 19, 2967.
7. Y. Shi, P. C. Simpson, J. R. Scherer, D. Weller, C. Skibola, M. T. Smith and R. A. Mathies, Anal. Chem., 1999, 71, 5354.
8. C. S. Effenhauser, G. J. M. Bruin and A. Paulus, Electrophoresis, 1997, 18, 2203.
9. C. S. Effenhauser, Microsystem Technology in Chemistry and Life Science, ed. A. Manz and H. Becker, Springer, Berlin, 1998, p. 51.
10. S. C. Jacobson and J. M. Ramsey, in Handbook of Capillary Electrophoresis, ed. J. P. Landers, 2nd edn., Boca Raton, 1997, p. 827.
11. P.-A. Auroux, D. Iossifidis, D. R. Reyes and A. Manz, Anal. Chem., 2002, 74, 2637.
12. Z. Liang, N. Chiem, G. Ocvirk, T. Tang, K. Fluri and D. J. Harrison, Anal. Chem., 1996, 68, 1040.
13. C. S. Effenhauser, A. Manz and H. M. Widmer, Anal. Chem., 1993, 65, 2637.
14. J. M. Ramsey and S. C. Jacobson, Apparatus and Method for Performing Electrodynamic Focusing on a Microchip, US Pat. 5,858,187, 1999.
15. S. C. Jacobson, R. Hergenroder, L. B. Koutny, R. J. Warmack and J. M. Ramsey, Anal. Chem., 1994, 66, 1107.
16. L. D. Hutt, D. P. Glavin, J. L. Bada and R. A. Mathies, Anal. Chem., 1999, 71, 4000.
17. S. Liu, Y. Shi, W. W. Ja and R. A. Mathies, Anal. Chem., 1999, 71, 566.
18. C.-X. Zhang and A. Manz, Anal. Chem., 2001, 73, 2656.
19. P. Bocek, M. Deml, P. Gebauer and V. Dolnik, Analytical Isotachophoresis, V. C. H. Publishers, Weinheim, Germany, 1987.
20. J. L. Beckers and P. Bocek, Electrophoresis, 2000, 21, 2747.
21. J. P. Quirino and S. Terabe, J. Microcolumn Sep., 1999, 11, 513.
22. S. C. Jacobson and J. M. Ramsey, Electrophoresis, 1995, 16, 481.
23. P. Gebauer, W. Thormann and P. Bocek, Electrophoresis, 1995, 16, 2039.
24. S. Krishnamoorthy, J. J. Feng and V. B. Makhijani, Analysis of Sample Transport in Capillary Electrophoresis Microchip Using Full-Scale Numerical Analysis, International Conference on Modeling and Simulation of Microsystems, Hilton Head, SC, 2001.
25. R. Kurnik, T. Boone, I. Gibbons, J. Wei and S. Williams, Simulation of Transient Isotachophoresis (Stacking) for Concentration of Samples in a Microfluidic Device, The Electrochemical Society, San Francisco, 2001, p. 384.
26. Z. Shihabi, J. Chromatogr. A, 2000, 902, 107.
27. M. Larsson and E. S. M. Lutz, Electrophoresis, 2000, 21, 2859.
28. F. Foret, E. Szoko and B. L. Karger, J. Chromatogr., 1992, 608, 3.
29. P. Gebauer, L. Krivankova, P. Pantuckova, P. Bocek and W. Thormann, Electrophoresis, 2000, 21, 2797.
30. H. Yang and R.-L. Chien, J. Chromatogr., A, 2001, 924, 155.
31. S. Singh, PCT WO 00/66607, US 2000.
32. S. Singh, T. Matray, H. Salimi-Moosavi, PCT WO 01/83502, US 2001.
33. T. D. Boone, Z. H. Fan, I. Gibbons, A. J. Ricco, H. Tan and S. J. Williams, Anal. Chem., 2002, 74, 78A.
34. T. M. Johnson, J. W. Perich, J. D. Bjorge, D. J. Fujita and H. C. Cheng, J. Peptide Res., 1997, 50, 365.
35. Q. Xue, A. Wainright, S. Gangakhedkar and I. Gibbons, Electrophoresis, 2001, 22, 4000.
36. A. Wainright, S. J. Williams, G. Ciambrone, Q. Xue, J. Wei and D. Harris, J. Chromatogr., A, 2002, 979, 69.
37. B. Jung, R. Bharadwaj and J. G. Santiago, Electrophoresis, submitted for publication.