The use of hypofractionated intensity-modulated irradiation in the treatment of glioblastoma multiforme: Preliminary results of a prospective trial

International Journal of Radiation Oncology Biology Physics

Volumn 58, Issue 1, 2004, Pages 247-252

  Sultanem, Khalil ^a,b   Patrocinio, Horacio ^a   Lambert, Christine ^a   Corns, Robert ^a   Leblanc, Richard ^a   Parker, William ^a   Shenouda, George ^a   Souhami, Luis ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Accelerated radiation therapy; Glioblastoma multiforme; Hypofractionated radiation therapy; Intensity modulated radiation therapy

Indexed keywords

BRAIN; CELLS; COMPUTERIZED TOMOGRAPHY; DISEASES; HISTOLOGY; IRRADIATION; RADIOTHERAPY; TOXICITY; TUMORS;

TREATMENT PLANNING;

ONCOLOGY;

CORTICOSTEROID; STEROID;

ADULT; AGED; BRAIN EDEMA; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GLIOBLASTOMA; HUMAN; MALE; OPTIC CHIASM; PRIORITY JOURNAL; RADIATION DOSE DISTRIBUTION; RADIATION DOSE FRACTIONATION; RADIATION INJURY; RADIATION RESPONSE; REVIEW; SURVIVAL RATE; TREATMENT OUTCOME; TREATMENT PLANNING; TUMOR VOLUME; VISUAL IMPAIRMENT;

EID: 0347624471     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(03)00819-8     Document Type: Article

References (25)

1. Mahley M.S., Mettlin C., Natarajan N., Laws E.R., Peace B.B. National survey of patterns of care for brain-tumor patients. J Neurosurg. 71:1989;826-836.
2. Yung W.K., Prados M.D., Yaya-Tur R., et al. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group. J Clin Oncol. 17:1999;2762-2771.
3. Stupp R., Dietrich P.Y., Ostermann K.S., et al. Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J Clin Oncol. 20:2002;1375-1382.
4. Fine H.A., Figg W.D., Jaeckle K., et al. A phase II trial of the anti-angiogenic agent, thalidomide, in patients with recurrent high grade gliomas. J Clin Oncol. 18:2000;708-715.
5. Muanza T., Shenouda G., Souhami L., et al. High dose tamoxifen and radiotherapy in patients with glioblastoma multiforme A phase IB study . Can J Neurol Sci. 27:(4):2000;302-306.
6. Buatti J.M., Friedman W.A., Bova F.J., Mendenhall W.M. Linac radiosurgery for high grade gliomas The University of Florida experience . Int J Radiat Oncol Biol Phys. 32:1995;205-210.
7. Sarkaria J.N., Mehta M.P., Loeffler J.S., et al. Radiosurgery in the initial management of malignant gliomas Survival comparison with the RTOG recursive partitioning analysis . Int J Radiat Oncol Biol Phys. 32:1995;931-941.
8. Cardinale R.M., Broaddus W.C., Benedict S.H., Schmidt-Ullrich R.K., Kavanagh B.K. Accelerated radiotherapy using weekly stereotactic conformal boosts for GBM. Int J Radiat Oncol Biol Phys. 48:2000;257.
9. Gutin P.H., Prados M.D., Phillips T.L., et al. External radiation followed by an interstitial high activity iodine-125 implant boost in the initial treatment of malignant gliomas NCOG study 6G-82-2 . Int J Radiat Oncol Biol Phys. 21:1991;601-606.
10. Laperriere N.J., Leung P.M., Mckenzie S., et al. Randomized study of brachytherapy in the initial management of patients with malignant astrocytoma. Int J Radiat Oncol Biol Phys. 41:1998;1005-1011.
11. Selker R.G., Shapiro W.R., Burger P., et al. NIH trial 87-01 A randomized comparison of surgery, external radiotherapy, and carmustine versus surgery, interstitial radiotherapy boost, external radiotherapy, and carmustine . Neurosurgery. 51:2002;343-355.
12. Sneed P.K., Gutin P.H., Larson D.A., et al. Patterns of recurrence of glioblastoma multiforme after external irradiation followed by implant boost. Int J Radiat Oncol Biol Phys. 29:(4):1994;719-727.
13. Curran W.J., Scott C.B., Horton J., et al. Recursive partitioning analysis of prognostic factors in three Radiation Therapy Oncology Group malignant glioma trials. J Natl Cancer Inst. 85:1993;704-710.
14. Walker M.D., Strike T.A., Sheline G.E. An analysis of dose-effect relationship in the radiotherapy of malignant gliomas. Int J Radiat Oncol Biol Phys. 5:1979;1725-1731.
15. Marks J.E., Wong J. The risk of cerebral radionecrosis in relation to dose, time and fractionation. Prog Exp Tumor Res. 29:1985;210-218.
16. Shenouda G., Souhami L., Freeman C.R., Hazel J., Lehnert S., Joseph L. Accelerated fractionation for high-grade cerebral astrocytomas. Preliminary treatment results. Cancer. 67:(9):1991;2247-2252.
17. Souhami L, Scott C, Brachman D, et al. Randomized prospective comparison of stereotactic radiosurgery (SRS) followed by conventional radiotherapy (RT) with BCNU to RT with BCNU alone for selected patients with supratentorial glioblastoma multiforme (GBM) [abstract]. Proc Am Soc Ther Rad Oncol (ASTRO) Int J Radiat Oncol Biol Phys 2002;54:94-95.
18. Chan J.L., Lee S.W., Frass B.A., et al. Survival and failure patterns of high grade glioma after three-dimensional conformal radiotherapy. J Clin Oncol. 20:2002;1635-1642.
19. Budach W., Gioioso D., Taghian A., Stuschke M., Suit H.D. Repopulation capacity during fractionated irradiation of squamous cell carcinomas and glioblastomas in vitro. Int J Radiat Oncol Biol Phys. 39:1997;743-750.
20. Lang O., Liebermeister E., Liesegang J., Sautter-Bihl M.L. Radiotherapy of glioblastoma multiforme. Feasibility of increased fraction size and shortened overall treatment. Strahlenther Onkol. 174:1998;629-632.
21. A Medical Research Council trial of two radiotherapy doses in the treatment of grades 3 and 4 astrocytoma. The Medical Research Council Brain Tumour Working Party. Br J Cancer 1991;64:769-774.
22. Slotman B.J., Kralendonk J.H., van Alphen H.A., Kamphorst W., Karim A.B. Hypofractionated radiation therapy in patients with glioblastoma multiforme Results of treatment and impact of prognostic factors . Int J Radiat Oncol Biol Phys. 34:1996;895-898.
23. Kelly P.J., Daumas-Duport C., Kispert D.B., Kall B.A., Scheithauer B.W., Illig J.J. Imaging-based stereotaxic serial biopsies in untreated intracranial glial neoplasms. J Neurosurg. 66:1987;865-874.
24. Hempen C., Weiss E., Hess C.F. Dexamethasone treatment in patients with brain metastases and primary brain tumors Do the benefits outweigh the side-effects? Support Care Cancer. 10:2002;322-328.
25. Loeffler J.S., Alexander E. 3rd, Shea W.M., et al. Radiosurgery as part of the initial management of patients with malignant gliomas. J Clin Oncol. 10:1992;1379-1385.