Light treatment of mood disorders

Dialogues in Clinical Neuroscience

Volumn 5, Issue 4, 2003, Pages 353-365

  Parry, Barbara L ^a   Maurer, Eva L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Depression; Light treatment; Mood disorder; Phototherapy; Seasonal affective disorder

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR STIMULATING AGENT; ANTIDEPRESSANT AGENT; BACLOFEN; CATECHOLAMINE; CITALOPRAM; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; FLUOXETINE; GROWTH HORMONE; IMIPRAMINE; LITHIUM; MELATONIN; NORADRENALIN; PAROXETINE; PLACEBO; SEROTONIN 1D AGONIST; SEROTONIN UPTAKE INHIBITOR; SUMATRIPTAN; TRICYCLIC ANTIDEPRESSANT AGENT; TRITIUM; TRYPTOPHAN;

ADOLESCENT; ADULT; BIPOLAR DISORDER; BRAIN BLOOD FLOW; CHILD; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CLINICAL TRIAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DEPRESSION; ELECTROENCEPHALOGRAM; HUMAN; HYPERSOMNIA; HYPOMANIA; LIGHT; LIGHT EXPOSURE; MAJOR DEPRESSION; MENTAL DISEASE; MOOD DISORDER; PERSONALITY DISORDER; PHOTOPERIODICITY; PHOTOSENSITIZATION; PHOTOTHERAPY; PREGNANCY; PSYCHOPHARMACOTHERAPY; PUERPERAL DEPRESSION; RETINA; REVIEW; SEASONAL AFFECTIVE DISORDER; SEASONAL VARIATION; THERMOREGULATION; TREATMENT OUTCOME;

EID: 0347621649     PISSN: 12948322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (159)

1. Kripke DF. Photoperiodic mechanisms for depression and its treatment. In: Perris C, Struwe G, Jansson B, eds. Biological Psychiatry. Amsterdam, The Netherlands: Elsevier; 1981;1249.
2. Kripke DF, Risch SC, Janowsky D. Bright white light alleviates depression. Psychiatry Res. 1983;10:105-112.
3. Spitzer RL, Endicott J, Robins E. Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry. 1978;35:773.
4. Hamilton M. A rating scale for depression. J Psychiatry Neurol Neurosurg. 1960;23:56.
5. Beck At, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:561.
6. Kripke DF, Risch S, Janowsky DS. Lighting up depression. Psychopharmacol Bull. 1983;19:526-530.
7. Lewy AJ, Kern HA, Rosenthal NE, Wehr TA. Bright artificial light treatment of a manic-depressive patient with a seasonal mood cycle. Am J Psychiatry. 1982;139:1496-1498.
8. Rosenthal NE, Sack DA, Gillin JC, et al. Seasonal affective disorder: a description of the syndrome and preliminary findings with light treatment. Arch Gen Psychiatry. 1984;41:72-80.
9. Rosenthal NE, Sack DA, Carpenter CJ, Parry BL, Mendelson WB, Wehr TA. Antidepressant effects of light in seasonal affective disorder. Am J Psychiatry. 1985;142:163-170.
10. Wehr TA, Jacobsen FM, Sack DA, Arendt J, Tamarkin L, Rosenthal NE. Phototherapy of seasonal affective disorder. Arch Gen Psychiatry. 1986;43:870-875.
11. Terman M, Terman JS, Quitkin FM, McGrath PJ, Stewart JW, Rafferty B. Light therapy for seasonal affective disorder: a review of efficacy. Neuropsychopharmacology. 1989;2:1-22.
12. Lewy AJ, Bauer VK, Cutler NL, et al. Morning vs evening light treatment of patients with winter depression. Arch Gen Psychiatry. 1998;55:890-896.
13. Sack RL, Lewy AJ, White DM, Singer CM, Fireman MJ, Vandiver R. Morning vs evening light treatment for winter depression: evidence that the therapeutic effects of light are mediated by circadian phase shifts. Arch Gen Psychiatry. 1990;47:343-351.
14. Avery DH, Khan A, Dager SR, Cox GB, Dunner DL. Bright light treatment of winter depression: morning versus evening light. Acta Psychiatr Scand. 1990;82:335-338.
15. James SP, Wehr TA, Sack DA, Parry BL, Rosenthal NE. Treatment of seasonal affective disorder with light in the evening. Br J Psychiatry. 1985;147:424-428.
16. Wirz-Justice A, Graw P, Krauchi K, et al. Light therapy in seasonal affective disorder is independent of time of day or circadian phase. Arch Gen Psychiatry. 1993;50:929-937.
17. Lafer B, Sachs GS, Labbate LA, Thibault A, Rosenbaum JF. Phototherapy for seasonal affective disorder: a blind comparison of three different schedules. Am J Psychiatry. 1994;151:1081-1083.
18. Wirz-Justice A, Anderson J. Morning light exposure for the treatment of winter depression: the one true light therapy? Psychopharmacol Bull. 1990;26:511-519.
19. Wirz-Justice A, Bucheli C, Graw P, Kielholz P, Fisch HU, Woggon B. Light treatment of seasonal affective disorder in Switzerland. Acta Psychiatr Scand. 1986;74:193-204.
20. Grota LJ, Yerevaian, Gupta K, Kruse J, Zborowski L. Phototherapy for seasonal major depressive disorder: effectiveness of bright light of high or low intensity. Psychiatry Res. 1989;29:29-35.
21. Labbate LA, Lafer B, Thibault A, Rosenbaum JF, Sachs GS. Influence of phototherapy treatment duration for seasonal affective disorder: outcome at 1 vs 2 weeks. Biol Psychiatry. 1995;38:747-750.
22. Byerley WF, Brown J, Lebegue B. Treatment of seasonal affective disorder with morning light. J Clin Psychiatry. 1987;48:447-448.
23. Wirz-Justice A, Schmid AC, Graw P, et al. Dose relationships of morning bright white light in seasonal affective disorder. Experientia. 1987;43:574-576.
24. Doghramji K, Gaddy JR, Stewart KT, Rosenthal NE, Brainard GC. Two-versus four-hour evening phototherapy of seasonal affective disorder. J Nerv Mental Dis. 1990;178:257-260.
25. Wirz-Justice A, Bucheli C, Schmid A, Graw. A dose relationship in bright white light treatment of seasonal depression. Am J Psychiatry. 1986;143:932-933.
26. Oren DA, Brainard GC, Johnston SH, Joseph-Vanderpool JR, Sorek E, Rosenthal NE. Treatment of seasonal affective disorder with green light and red light. Am J Psychiatry. 1991;148:509-511.
27. Stewart KT, Gaddy JR, Byrne B, Miller S, Brainard GC. Effects of green or white light for treatment of seasonal depression. Psychiatry Res. 1991;38:261-270.
28. Lam RW, Buchanan A, Clark CM, Remick RA. Ultraviolet versus non-ultraviolet light therapy for seasonal affective disorder. J Clin Psychiatry. 1991;52:213-216.
29. Bielski RJ, Mayor J, Rice J. Phototherapy with broad spectrum white fluorescent light: a comparative study. Psychiatry Res. 1992;43:167-175.
30. Brainard GC, Sherry RG, Skwerer RG, Waxler M, Kelly K, Rosenthal NE. Effects of different wavelengths in seasonal affective disorder. J Affect Disord. 1990;20:209-216.
31. Levitt AJ, Joffe RT, King E. Dim versus bright red (light-emitting diode) light in the treatment of seasonal affective disorder. Acta Psychiatr Scand. 1994;89:341-345.
32. Avery D, Bolte MA, Millet M. Bright dawn simulation compared with bright morning light in the treatment of winter depression. Acta Psychiatr Scand. 1992;85:430-434.
33. Avery DH, Bolte AP, Cohen S, Millet MS. Gradual versus rapid dawn simulation treatment of winter depression. J Clin Psychiatry. 1992;53:359-363.
34. Avery DH, Bolte MA, Dager SR, et al. Dawn simulation treatment of winter depression: a controlled study. Am J Psychiatry. 1993;150:113-117.
35. Norden MJ, Avery DH. A controlled study of dawn simulation in subsyndromal winter depression. Acta Psychiatr Scand. 1993;88:67-71.
36. Avery DH, Bolte AP, Wolfson JK, Kazaras AL. Dawn simulation compared with a dim red signal in the treatment of winter depression. Biol Psychiatry. 1994;36:181-188.
37. Lingjaerde O, Foreland AR, Dankertsen J. Dawn simulation vs lightbox treatment in winter depression: a comparative study. Acta Psychiatr Scand. 1998;98:73-80.
38. Avery DH, Eder DN, Bolte MA, et al. Dawn simulation and bright light in the treatment of SAD: a controlled study. Biol Psychiatry. 2001;50:205-216.
39. Stewart KT, Gaddy JR, Benson DM, Byrne B, Doghramji K, Brainard GC. Treatment of winter depression with a portable head-mounted phototherapy device. Prog Neuropsychopharmacol Biol Psychiatry. 1990;14:569-578.
40. Joffe RT, Moul DE, Lam RW, et al. Light visor treatment for seasonal affective disorder: a multicenter study. Psychiatry Res. 1993;46:29-39.
41. Teicher MH, Glod CA, Oren DA, et al. The phototherapy light visor: more to it than meets the eye. Am J Psychiatry. 1995;152:1197-1202.
42. Levitt AJ, Wesson VA, Joffe RT, Maunder RG, King EF. A controlled comparison of light box and head-mounted units in the treatment of seasonal depression. J Clin Psychiatry. 1996;57:105-110.
43. Magnusson A, Kristbjarnarson H. Treatment of seasonal affective disorder with high-intenisty light. A phototherapy study with an Icelandic group of patients. J Affect Disord. 1991;21:141-147.
44. Lingjaerde O, Reichborn-Kjennerud T, Haggag A, Gartner I, Berg EM, Narud K. Treatment of winter depression in Norway. Short- and long-term effects of 1500-lux white light for 6 days. Acta Psychiatr Scand. 1993;88:292-299.
45. Graw P, Gisin B, Wirz-Justice A. Follow-up study of seasonal affective disorder in Switzerland. Psychopathotogy. 1997;30:208-214.
46. Magnusson A. Light therapy to treat winter depression in adolescents in Iceland. J Psychiatry Neurosci. 1998;23:118-122.
47. Lam RW. Morning light therapy for winter depression: predictors of response. Acta Psychiatr Scand. 1994;89:97-101.
48. Terman M, Amira L, Terman JS, Ross DC. Predictors of response and non-response to light treatment for winter depression. Am J Psychiatry. 1996;153:1423-1429.
49. Schwartz PJ, Brown C, Wehr TA, Rosenthal NE. Winter seasonal affective disorder: a follow-up study of the first 59 patients of the National Institute of Mental Health Seasonal Studies Program. Am J Psychiatry. 1996;153:1028-1036.
50. Postolache TT, Hardin TA, Myers FS, et al. Greater improvement in summer than with light treatment in winter in patients with seasonal affective disorder. Am J Psychiatry. 1998;155:1614-1616.
51. Lee TMC, Chan CCH. Dose-response relationship of phototherapy for seasonal affective disorder: a meta-analysis. Acta Psychiatr Scand. 1999;99:315-323.
52. Levitt AJ, Lam RW, Levitan R. A comparison of open treatment of seasonal major and minor depression with light therapy. J Affect Disord. 2002;71:243-248.
53. Lam RW, Tam EM, Shiah IS, Yatham LN, Zis AP. Effects of light therapy on suicidal ideation in patients with winter depression. J Clin Psychiatry. 2000;61:30-32.
54. Williams JBW, Link MJ, Rosentahl NE, et al. Structured Interview Guide for the Hamilton Depression Rating Scale, Seasonal Affective Disorders Version (SIGHSAD). New York, NY: New York State Psychiatric Institute; 1998.
55. Meesters Y, Lambers PA, Jansen JHC, Bouhuys AL, Beersma DGM, van den Hoofdakker RH. Can winter depression be prevented by light treatment? J Affect Disord. 1991;23:75-79.
56. Meesters Y, Jansen JH, Beersma DGM, Bouhuys AL, van den Hoofdakker RH. Early light treatment can prevent an emerging winter depression from developing into a full-blown depression. J Affect Disord. 1993;29:41-47.
57. Meesters Y, Jansen JHC, Beersma DGM, Bouhuys AL, van den Hoofkadder RH. An attempt to prevent winter depression by light exposure at the end of September. Biol Psychiatry. 1994;35:284-286.
58. Partonen T, Lonnqvist J. Prevention of winter seasonal affective disorder by bright-light treatment. Psychol Med. 1996;26:1075-1080.
59. Avery DH, Khan A, Dager SR, Cohen S, Cox GB, Dunner DL. Morning or evening bright light treatment of winter depression. The significance of hypersomnia. Biol Psychiatry. 1991;229:117-126.
60. Lam RW, Buchanan A, Mador JA, Corral MR. Hypersomnia and morning light therapy for winter depression. Biol Psychiatry. 1992;31:1062-1064.
61. Partonen T. Effects of morning light treatment on subjective sleepiness and mood in winter depression. J Affect Disord. 1994;30:99-108.
62. Wirz-Justice A, van der Velde P, Bucher A, Nil R. Comparison of light treatment with citalopram in winter depression: a longitudinal single case study. Int Clin Psychopharmacol. 1992;7:109-116.
63. Ruhrmann S, Kasper S, Hawellek B, et al. Effects of fluoxetine versus bright light in the treatment of seasonal affective disorder. Psychol Med. 1998;28:923-933.
64. Ghadirian AM, Murphy BEP, Gendron MJ. Efficacy of light versus tryptophan therapy in seasonal affective disorder. J Affect Disord. 1998;50:23-27.
65. Sher L, Matthews JR, Turner EH, Postolache TT, Katz KS, Rosenthal NE. Early response to light therapy partially predicts long-term antidepressant effects in patients with seasonal affective disorder. J Psychiatry Neurosci. 2001;26:336-338.
66. Eastman C. Natural summer and winter sunlight exposure patterns in seasonal affective disorder. Physiol Behav. 1990;48:611-616.
67. Wirz-Justice A, Graw P, Krauchi K, et al. Natural light treatment of seasonal affective disorder. J Affect Disord. 1996;37:109-120.
68. Avery DH, Kizer D, Bolte MA, Hellekson C. Bright light therapy of subsyndromal seasonal affective disorder in the workplace: morning vs afternoon exposure. Acta Psychiatr Scand. 2001;103:267-274.
69. Terman M, Reme CE, Rafferty B, Gallin PF, Terman JS. Bright light therapy for winter depression: potential ocular effects and theoretical implications. Photochem Photobiol. 1990;51:781-792.
70. Bauer MS, Kurtz JW, Rubin LB, Marcus JG. Mood and behavioral effects of 4-week light treatment in winter depressives and controls. J Psychiatr Res. 1994;28:135-145.
71. Stewart JW, Quitkin FM, Terman M, Terman JS. Is seasonal affective disorder a variant of atypical depression? Differential response to light therapy. Psychiatry Res. 1990;33:121-128.
72. Partonen T, Lonnqvist J. The influence of comorbid disorders and of continuation light treatment on remission and recurrence in winter depression. Psychopathology. 1995;28:256-262.
73. Swedo SE, Allen AJ, Glod CA. A controlled trial of light therapy for the treatment of pediatric seasonal affective disorder. J Am Acad Child Adolesc Psychiatry. 1997;36:816-821.
74. Wileman SM, Eagles JM, Andrew JE. Light therapy for seasonal affective disorder in primary care. Br J Psychiatry. 2001;178:311-316.
75. Eastman CI, Lahmeyer HW, Watell LG, Good GD, Young MA. A placebo-controlled trial of light treatment for winter depression. J Affect Disord. 1992;26:211-222.
76. Richter P, Bouhuys AL, van den Hoofdakker RH, et al. Imaginary versus real light for winter depression. Biol Psychiatry. 1992;31:531-537.
77. Terman M, Terman JS. Treatment of seasonal affective disorder with a high-output negative ionizer. J Altern Complementary Med. 1995;1:87-92.
78. Eastman CI, Young MA, Fogg LF, Liu L, Meaden PM. Bright light treatment of winter depression. A placebo-controlled trial. Arch Gen Psychiatry. 1998;55:883-889.
79. Terman M, Terman JS, Ross DC. A controlled trial of timed bright light and negative air ionization for treatment of winter depression. Arch Gen Psychiatry. 1998;55:875-882.
80. Yerevanian BI, Anderson JL, Grota LJ, Bray M. Effects of bright incandescent light on seasonal and nonseasonal major depressive disorder. Psychiatry Res. 1986;18:355-364.
81. Volz HP, Mackert A, Stieglitz RD, Muller-Oerlinghausen B. Effect of bright white light therapy on non-seasonal depressive disorder. J Affect Disord. 1990;19:15-21.
82. Mackert A, Volz HP, Stieglitz B, Muller-Oerlinghausen B. Effects of white light on non-seasonal depressive disorder. Pharmacopsychiatry. 1990;23:151-154.
83. Mackeert A, Volz HP, Stieglitz, Muller-Oerlinghausen B. Phototherapy in nonseasonal depression. Biol Psychiatry. 1991;30:257-268.
84. Thalen BE, Kjellman BF, Morkrid L, Wibom R, Wetterberg L. Light treatment in seasonal and nonseasonal depression. Acta Psychiatr Scand. 1995;91:352-360.
85. Yamada N, Martin-Iverson MT, Daimon K, Tsujimoto T, Takahashi S. Clinical and chronobiological effects of light therapy on nonseasonal affective disorders. Biol Psychiatry. 1995;37:866-873.
86. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed, revised, Washington, DC: American Psychiatric Association; 1987.
87. Kripke DF. Light treatment for nonseasonal depression: speed, efficacy and combined treatment. J Affect Disord. 1998;49:109-117.
88. Wirz-Justice A, Graw P, Roosli H, Glauser G, Fleischhauer J. An open trial of light therapy in hospitalized major depression. J Affect Disord. 1999;52:291-292.
89. Kripke DF, Mullaney DJ, Klauber MR, Risch SC, Gillin JC. Controlled trial of bright light for nonseasonal major depressive disorders. Biol Psychiatry. 1992;31:119-134.
90. Beauchemin KM, Hays P. Sunny hospital rooms expedite recovery from severe and refractory depressions. J Affect Disord. 1996;40:49-51.
91. Beauchemin KM, Hays P. Phototherapy is a useful adjunct in the treatment of depressed in-patients. Acta Psychiatr Scand. 1997;95:424-427.
92. Benedetti F, Colombo C, Barbini B, Campori E, Smeraldi E. Morning sunlight reduces length of hospitalization in bipolar depression. J Affect Disord. 2001;62:221-223.
93. Sumaya IC, Rienzi BM, Deegan JF, Moss DE. Bright light treatment decreases depression in institutionalized older adults: a placebo-controlled crossover study. J Gerontol. 2001;56A:M356-M360.
94. Levitt AJ, Joffe RT, Kennedy SH. Bright light augmentation in antidepressant nonresponders. J Clin Psychiatry. 1991;52:336-337.
95. Holsboer-Trachsler E, Hemmeter U, Hatzinger M, Seifritz E, Gerhard U, Hobi V. Sleep deprivation and bright light as potential augmenters of antidepressant drug treatment-neurobiological and psychometric assessment of course. J Psychiatr Res. 1994;28:381-399.
96. Neumeister A, Goessler R, Lucht M, Kapitany T, Bamas C, Kasper S. Bright light therapy stabilizes the antidepressant effect of partial sleep deprivation. Biol Psychiatry. 1996;39:16-21.
97. Muller MJ, Seifritz E, Hatzinger M, Hemmeter U, Holsboer-Trachsler E. Side effects of adjunct light therapy in patients with major depression. Eur Arch Psychiatry Clin Neurosci. 1997;247:252-258.
98. Prasko J, Horacek J, Klaschka J, Kosova J, Ondrackova I, Sipek J. Bright light therapy and/or imipramine for inpatients with recurrent non-seasonal depression. Neuroendocrinol Lett. 2002;23:109-113.
99. Loving RT, Kripke DF, Shuchter SR. Bright light augments antidepressant effects of medication and wake therapy. Depress Anxiety. 2002;16:1-3.
100. Krauss SS, Depue RA, Aribisi PA, Spoont M. Behavioral engagement level, variability and diurnal rhythm as a function of bright light in bipolar II seasonal affective disorder: an exploratory study. Psychiatry Res. 1992;43:147-160.
101. Papatheodorou G, Kutcher S. The effect of adjunctive light therapy on ameliorating breakthrough depressive symptoms in adolescent-onset bipolar disorder. J Psychiatry Neurosci. 1995;20:226-232.
102. Praschak-Rieder N, Neumeister A, Hesselmann B, Willeit M, Barnas C, Kasper S. Suicidal tendencies as a complication of light therapy for seasonal affective disorder: a report of three cases. J Clin Psychiatry. 1997;58:389-392.
103. Wirz-Justice A, Quinto C, Cajochen C, Werth E, Hock C. A rapid-cycling bipolar patient treated with long nights, bedrest, and light. Biol Psychiatry. 1999;45:1075-1077.
104. Colombo C, Lucca A, Benedetti F, Barbini B, Campori E, Smeraldi E. Total sleep deprivation combined with lithium and light therapy in the treatment of bipolar depression: replication of main effects and interaction. Psychiatry Res. 2000;95:43-53.
105. Parry BL, Rosentahl NE, Tamarkin L, Wehr TA. Treatment of a patient with seasonal premenstrual syndrome. Am J Psychiatry. 1987;144:762-766.
106. Parry BL, Berga SL, Mostofi N, Sependa PA, Kripke DF, Gillin JC. Morning versus evening bright light treatment of late luteal phase dysphoric disorder. Am J Psychiatry. 1989;146:1215-1217.
107. Parry BL, Mahan AM, Mostofi N, Klauber MR, Lew GS, Gillin JC. Light therapy of late luteal phase dysphoric disorder: an extended study. Am J Psychiatry. 1993;150:1417-1419.
108. Lam RW, Carter D, Misri S, Kuan AJ, Yatham LN, Zis AP. A controlled study of light therapy in women with late luteal phase dysphoric disorder. Psychiatry Res. 1999;86:185-192.
109. Oren DA, Wisner KL, Spinelli M, et al. An open trial of morning light therapy for treatment of antepartum depression. Am J Psychiatry. 2002;159:666-669.
110. Corral M, Kuan A, Kostaras D. Bright light therapy's effect on post-partum depression. Am J Psychiatry. 2000;157:303-304.
111. Lewy AJ, Sack RL, Miller S, Hoban TM. Antidepressant and circadian phase-shifting effects of light. Science. 1987;235:352-354.
112. Terman JS, Terman M, Lo ES, Cooper TB. Circadian time of morning light administration and therapeutic response in winter depression. Arch Gen Psychiatry. 2001;58:69-75.
113. Terman M, Terman JS, Quitkin FM, et al. Response of the melatonin cycle to phototherapy for seasonal affective disorder. J Neural Transm. 1988;72:147-165.
114. Winton F, Corn T, Huson LW, Franey C, Arendt J, Checkley SA. Effects of light treatment upon mood and melatonin in patients with seasonal affective disorder. Psychol Med. 1989;19:585-590.
115. Danilenko KV, Putilov AA, Russkikh GS, Duffy LK, Ebbesson SOE. Diurnal and seasonal variations of melatonin and serotonin in women with seasonal affective disorder. Arct Med Res. 1994;53:137-145.
116. Partonen T. Involvement of melatonin and serotonin in winter depression. Medical Hypotheses. 1994;43:165-166.
117. Rice J, Mayor J, Tucker A, Bielski RJ. Effect of light therapy on salivary melatonin in seasonal affective disorder. Psychiatry Res. 1995;56:221-228.
118. Thalen BE, Kjellman BF, Morkrid L, Wetterberg L. Melatonin in light treatment of patients with seasonal and nonseasonal depression. Acta Psychiatr Scand. 1995;92:274-284.
119. Rao ML, Muller-Oerlinghausen BM, Mackert A, Stieglitz RD, Strebel B, Volz HP. The influence of phototherapy on serotonin and melatonin in non-seasonal depression. Pharmacopsychiatry. 1990;23:155-158.
120. Rao ML, Muller-Oerlinghausen B, Macker A, Strebel B, Stieglitz RD. Blood serotonin, serum melatonin and light therapy in healthy subjects and in patients with nonseasonal depression. Acta Psychiatr Scand. 1992;86:127-132.
121. Mellerup ET, Errebo I, Molin J, Plenge P, Dam H. Platelet paroxetine binding and light therapy in winter depression. J Affect Disord. 1993;29:11-15.
122. Schwartz PJ, Murphy DL, Wehr TA, et al. Effects of metachorophenylpiperazine infusions in patients with seasonal affective disorder and healthy control subjects. Arch Gen Psychiatry. 1997;54:375-385.
123. Stain-Malmgren R, Kjellman BF, Aberg-Wistedt A. Platelet serotonergic functions and light therapy in seasonal affective disorder. Psychiatry Res. 1998;78:163-172.
124. Lam RW, Zis AP, Grewal A, Delgado PL, Charney DS, Krystal JH. Effects of rapid tryptophan depletion in patients with seasonal affective disorder in remission after light therapy. Arch Gen Psychiatry. 1996;53:41-44.
125. Neumeister A, Praschak-Rieder P, Hesselmann B, Rao ML, Gluck J, Kasper S. Effects of tryptophan depletion on drug-free patients with seasonal affective disorder during a stable response to bright light therapy. Arch Gen Psychiatry. 1997;554:133-138.
126. Neumeister A, Turner E, Matthews JR, et al. Effects of tryptophan depletion vs catecholamine depletion in patients with seasonal affective disorder in remission with light therapy. Arch Gen Psychiatry. 1998;55:524-530.
127. Szadoczky E, Falus A, Arato M, Nemeth A, Teszeri G, Moussong-Kovacs E. Phototherapy increases platelet imipramine binding in patients with winter depression. J Affect Disord. 1989;16:121-125.
128. Szadoczky E, Falus A, Nemeth A, Teszeri G, Moussong-Kovacs E. Effect of phototherapy on 3H-imipramine binding sites in patients with SAD, non-SAD and in healthy controls. J Affect Disord. 1991;22:179-184.
129. Anderson JL, Vasile RG, Mooney JJ, Bloomingdale KL, Samson JA, Schildkraut JJ. Changes in norepinephrine output following light therapy for fall/winter seasonal depression. Biol Psychiatry. 1992;32:700-704.
130. Rudorder MV, Skwerer RG, Rosenthal NE. Biogenic amines in seasonal affective disorder: effects of light therapy. Psychiatry Res. 1993;46:19-28.
131. Partonen T. Prolactin in winter depression. Medical Hypotheses. 1994;43:163-164.
132. Lingjaerde O, Reichborn-Kjennerud T, Haug E. Thyroid function in seasonal affective disorder. J Affect Disord. 1995;33:39-45.
133. Thalen BE, Morkrid L, Kjeliman BF, Wetterberg L. Cortisol in light treatment of seasonal and non-seasonal depression: relationship between melatonin and cortisol. Acta PsychiatrScand. 1997;96:385-394.
134. Partonen T. A mechanism of action underlying the antidepressant effect of light. Medical Hypotheses. 1995;45:33-34.
135. 1D agonist) challenge in seasonal affective disorder: effects of light therapy. Biol Psychiatry. 1997;42:24-29.
136. Shiah IS, Robertson HA, Lam RW, Yatham LN, Tam EM, Zis AP. Growth hormone response to baclofen in patients with seasonal affective disorder: effects of light therapy. Psychonueroendocrinology. 1999;24:143-153.
137. Oren D. Bilirubin, REM sleep, and phototransduction of environmental time cues. A hypothesis. Chronobiol Int. 1997;14:319-329.
138. Oren DA, Desan PH, Boutros N, Anand A, Charney DS. Effects of light on low nocturnal bilirubin in winter depression: a preliminary report. Biol Psychiatry. 2002;51:422-425.
139. Dietzel M, Saletu B, Lesch OM, Sieghart W, Schjerve M. Light treatment in depressive illness. Polysomnographic, psychometic and neuroendocrinological findings. Eur Neurol Suppl. 1986;25:93-103.
140. Partonen T, Appelberg B, Partinen M. Effects of light treatment on sleep structure in seasonal affective disorder. Eur Arch Psychiatry Clin Neurosci. 1993;242:310-313.
141. Allen JJ, Iacono WG, Depue RA, Arbisi P. Regional electroencephalographic asymmetries in bipolar seasonal affective disorder before and after exposure to bright light. Biol Psychiatry. 1993;33:642-646.
142. Volf NV, Senkova NI, Danilenko KV, Putilov AA. Hemispheric language lateralization in seasonal affective disorder and light treatment. Psychiatry Res. 1993;47:99-108.
143. Brunner DP, Krauchi K, Dijk DJ, Leonhardt G, Haug HJ, Wirz-Justice A. Sleep electroencephalogram in seasonal affective disorder and in control women: effects of midday light treatment and sleep deprivation. Biol Psychiatry. 1996;40:485-496.
144. Fritzsche M, Heller R, Hill H, Kick H. Sleep deprivation as a predictor of response to light therapy in major depression. J Affect Disord. 2001;62:207-215.
145. Dilsaver SC. Neurobiologic effects of bright artificial light. Brain Res Rev 1989;14:311-333.
146. Rosenthal NE, Levendosky AA, Skwerer RG, et al. Effects of light treatment on core body temperature in seasonal affective disorder. Biol Psychiatry. 1990;27:39-50.
147. Eastman CI, Gallo LC, Lahmeyer HW, Fogg LF. The circadian rhythm of temperature during light treatment for winter depression. Biol Psychiatry. 1993;34:210-220.
148. Avery DH, Dahl K, Savage MV, et al. Circadian temperature and cortisol rhythms during a constant routine are phase-delayed in hypersomnic winter depression. Biol Psychiatry. 1997;41:1109-1123.
149. Schwartz PJ, Rosentahl NE, Turner EH, Drake CL, Liberty V, Wehr TA. Seasonal variation in core temperature regulation during sleep in patients with winter seasonal affective disorder. Biol Psychiatry. 1997;42:122-131.
150. Schwartz PJ, Rosenthal NE, Kajimura N, et al. Ultradian oscillations in cranial thermoregulation and electroencephalographic slow-wave activity during sleep are abnormal in humans with annual winter depression. Brain Res. 2000;866:152-167.
151. Seggie J, Canny C, Mai F, McCrank E, Waring E. Antidepressant medication reverses increased sensitivity to light in depression: preliminary report. Prog Neuropsychopharmacol Biol Psychiatry. 1989;13:537-541.
152. Terman S, Terman M. Photic and scotopic light detection in patients with SAD and control subjects. Biol Psychiatry. 1999;46:1642-1648.
153. Lam RW, Buchanan A, Mador JA, Corral MR, Remick RA. The effects of ultraviolet-A wavelengths in light therapy for seasonal depression. J Affect Disord. 1992;24:237-244.
154. Lasko TA, Kripke DF, Elliot JA. Melatonin suppression by illumination of upper and lower visual fields. J Biol Rhythms. 1999;14:122-125.
155. Vasile RG, Sachs G, Anderson JL, Lafer B, Matthews E, Hill T. Changes in regional cerebral blood flow following light treatment for seasonal affective disorder: responders versus nonresponders. Biol Psychiatry. 1997;42:1000-1005.
156. Rechlin T, Weis M, Schneider K, Zimmermann U, Kaschka WP. Does bright-light therapy influence autonomic heart-rate parameters? J Affect Disord. 1995;34:131-137.
157. Avissar S, Schreiber G, Nechamkin Y, et al. The effects of seasons and light therapy on G protein levels in mononuclear leukocyctes of patients with seasonal affective disorder. Arch Gen Psychiatry. 1999;56:178-183.
158. Oren DA, Berman RM, Anand A, Charney DS. No effect of light on basal glucagon levels in winter seasonal depressives and comparison subjects. Psychiatry Res. 2000;94:263-266.
159. Leu SJ, Shiah IS, Yatham LN, Cheu YM, Lam RW. Immune-inflammatory markers in patients with seasonal affective disorder: effects of light therapy. J Affect Disord. 2001;63:27-34.