Examination of carbadox genotoxicity in vitro and in vivo

Acta Veterinaria

Volumn 50, Issue 5-6, 2000, Pages 387-396

  Biljana, Marković ^a   Stanimirovic Z ^a   Marijana, Vučinić ^a   Cupic V ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Bone marrow cells; Carbadox; Chromosomal changes; DNA damage; Genotoxicity; Peripheral blood lymphocytes; Sister chromatid exchanges

Indexed keywords

ANIMALIA; SUS SCROFA;

EID: 0347616713     PISSN: 05678315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Bil V, Kren V, 1992; Teratogenicity testing based on the interaction with a mutant allele. Fol Biol Praha. 38: 40-47.
2. Brogger A, 1982; Cytogenetic, Cell Genet 33. 14-19.
3. Carrano AV, Thompson LH, Lindl PA, Minkler JL, 1978; Sister chromatid exhanges as an indicator of mutagenesis. Nature, 271: 551-553.
4. Carrano AV, Minkler JL, Steka DG, Moore DH, 1980; Variation in the baseline sister chromatid exhange frequency in human lymphocytes. Environ mut, 2: 325-337.
5. Carrano AV, Thompson L, 1981; Sister chromatid exhanges and single gene mutation. "Sister chromatid exhanges" (Ed. S. Wolff) Willey, New York, 321-333.
6. Crosen PE, Drets ME, Arrighi FE, Jonston DA, 1977; Analysis of the frequency and distribution of sister chromatid exhanges in cultured human lymphocytes. Hum Genet, 35: 345-352.
7. Cihak R, Vontorkova A, 1983; Cytogenetic effects of quinoxaline-1,4 dioxide-type growth promotoring agents Micronucleus test in rats. Mutat Res 117: 311-316.
8. FAO/WHO 1990; Evaluation of certain veterinary drug residues in food: thirty-sixth report of the joint FAO/WHO expert committee on food additives. WHO Tech Rep Ser 799 1990 12525. (c) 982-1994. Roy. Pharm. soc. G. B. Vol. 81 Exp 9/30/94.
9. Hsu TC, Patton JI, 1969; Bone marrow preparations for chromosome studies. In Benirschke, V. (ed) Comparative mammalian cytogenetices, Springer Verlag, Berlin, Heilderberg, New York, p. 454-460.
10. Irans DR, 1985; Toxicology of the Blood and Bone Marow Raven In Press New York. Jager, LP., Vroomen, LH., 1990. Toxicological considerations in the evaluation of veterinary drugs.Toxicol, 15 727-735.
11. Kato H, 1980; Temperature-dependence of sister chromatid exchange. An implication change. Cancer Gene. Cytogenet, 2: 61-67.
12. Lilp JG, 1981; Cytol (USSR) XXIII, 10: 1174-1179.
13. Marković B, 1996; Genotoksični efekat rôdenticida "Rosol" kod laboratorijskog misa BALB/c soja.Magistarska teza, Univerzitet u Beogradu.
14. Marković B, Stanimirović Z, Vučinić M, 1996; Uticaj organofosfatnih insekticida i njihovih rezidua i zemljišta i hrane na naslednu osnovu i reproduktivne sposobnosti i zdravstveno stanje ljudi i životinja. Zbornik radova VII Simpozijum životne sredine, Sutomore.
15. Marković B, 1999; Genotoksični efekat antibiotskih preparata Carbadox, Gastrogal 10 i Tiamulin S. Doktorska disertacija, Biološki fakultet, Univerzitet u Beogradu
16. Okinava RT, Berhart BJ, Chen JD, 1981; Comparison between sister chromatid exchange and mytagenicity following exogenous metabolic activation of promutagens. Mutation Res, 91. 57-61.
17. Ohta T, 1984; The SOS function inducing activity of chemical mutagen in Escherichia coli. Mutation Res, 131: 101-109.
18. Perry P, Evans H J, 1975; Cytological detection of mutagen-carcinogen exposure by sister chromatid exhange. Nature, 258: 121-125.
19. Szabova E, 1988; Cytogenetic effects of non-antibiotic growth stimulators on bone marrow cells in mice. Bratisi-Leklisty, 89: 369-372.
20. Stanimirović Z, 1995; Komparativne analize prirodnog i indukovanog polimorfizma hromozoma kod vrste Mus musculus, Linne 1758. Doktorska disertacija, Univerzitet u Beogradu.
21. Stanimirović Z, Vučinić Marijana, Soldatović B, Marković Biljana, 1997; Genotoxicity and potential chemosterilant effects of Rosol, Acta Veterinaria, 47, 4, 237-246.
22. Stanimirović Z, Vučinić M, Soldatović B, 1998; Citogenetičke promene ćelija kostne srži pacova Wistar soja indukovane levamizol hidrohloridom. Acta Veterinaria 48, 4, 255-262.
23. Truhaut R, Ferrando R, Faccini JM, Monro AM, 1981; Negative resuls of carcinogenicity bioassay of methyl carbazate in rats: significance for the toxicological evalution of carbadox. Toxicol, 22; 219-221.
24. Vander Molen EJ, De Graft GJ, Spierenburg TJ, Naburus MJ, Baars AJ, Jeger L P, 1986; Hypoaldosteronism in piglets induced by carbadox. Experientia, 42: 1247-1249
25. Vaughan-Dellarso V L, Marvournin K H, Tice R R, 1985; Aneuploidy and health risk assessment: Future directions. Environ Mutagen, 46: 40-45.
26. Vučinić M, 1994; Uticaj kombinovane intragastrične aplikacije Bezalkonijum hlorida i Varfarin natrijuma na citogenetičke promene ćelije kostne srži i semenika laboratorijskih miševa. Doktorska disertacija, Univerzitet u Beogradu.
27. WHO 1985; Guide to Short-term Test for Detecting Mutagenic and Cancerogenic, Chemicals. Enviromental Health Criteria 51 Vqamnala.
28. Yen JT, Nienaber JA, 1992; Influence of carbadox on fasting oxygen consumptionbes by portal vein-drained organs and by the whole animal in growing pigs. J Anim Sci, 70: 478-483.
29. Yen JT, Pond WC, 1993; Effects of carbadox copper, or Yucca shidigera extract on growth performance and visceral weight of young pigs. J Anim Sci, 71: 2140-2146.
30. Yen JT, Pond WC, 1990; Effect of carbadox on net absorption of ammonia and glucose into hepatic portal vein of growing pigs. J Anim Sci 68: 4236-4242.
31. Zimonjić D, Savković N, Ancrossed d signelković M, 1990; Genotoksični agensi efekti, principi, i metodologija detekcija. Naučna knjiga, Beograd.