Cardiac near-field morphology during conduction around a microscopic obstacle - A computer simulation study

Annals of Biomedical Engineering

Volumn 31, Issue 10, 2003, Pages 1206-1212

  Plank, G ^a   Vigmond, E ^a   Leon, L J ^a   Hofer, E ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Cardiac tissue; Conduction obstacle; Direction of propagation; Electric field; Electrode array; Vector loop morphology

Indexed keywords

BIOELECTRIC POTENTIALS; CARDIOVASCULAR SYSTEM; ELECTRIC CONDUCTIVITY; ELECTRIC FIELDS; ELECTRODES; MORPHOLOGY; VECTORS; WAVE PROPAGATION;

CARDIAC TISSUE; DIRECTION OF PROPAGATION; ELECTRODE ARRAY; VECTOR LOOP MORPHOLOGY;

TISSUE;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; COMPUTER SIMULATION; CONNECTIVE TISSUE; ELECTROCARDIOGRAPHY; ELECTROSTIMULATION; HEART MUSCLE CONDUCTION SYSTEM; HISTOLOGY; HUMAN; METHODOLOGY; MICROELECTRODE; PHYSIOLOGY; SYNAPTIC TRANSMISSION;

ANIMALS; BODY SURFACE POTENTIAL MAPPING; COMPUTER SIMULATION; CONNECTIVE TISSUE; ELECTRIC STIMULATION; HEART CONDUCTION SYSTEM; HUMANS; MICROELECTRODES; MODELS, CARDIOVASCULAR; MODELS, NEUROLOGICAL; SYNAPTIC TRANSMISSION;

EID: 0347596460     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.1615573     Document Type: Article

References (19)

1. Azene, E. M., N. A. Trayanova, and E. Warman. Wave front-obstacle interactions in cardiac tissue: A computational study. Ann. Biomed. Eng. 29:35-46, 2001.
2. Cabo, C., A. M. Pertsov, W. T. Baxter, J. M. Davidenko, R. A. Gray, and J. Jalife. Wave-front curvature as a cause of slow conduction and block in isolated cardiac muscle. Circ. Res. 75:1014-1028, 1994.
3. Geselowitz, D. B., R. C. Barr, M. S. Spach, and W. T. Miller, III. The impact of adjacent isotropic fluids on electrograms from anisotropic cardiac muscle-A modeling study. Circ. Res. 51:602-613, 1982.
4. Goette, A. et al. Increased expression of extracellular signal-regulated kinase and angiotensin-converting enzyme in humanatria during atrial fibrillation. J. Am. Coll. Cardiol. 35:1669-1677, 2000.
5. Hocini, M., P. Loh, S. Y. Ho, D. Sanchez-Quintana, B. Thibault, J. M. T. De-Bakker, and M. J. Janse. Anisotropic conduction in the triangle of Koch of mammalian hearts: Electrophysiologic and anatomic correlations. J. Am. Coll. Cardiol. 31:629-636, 1998.
6. Hofer, E., G. Urban, M. S. Spach, I. Schafferhofer, G. Mohr, and D. Platzer. Measuring activation patterns of the heart at a microscopic size scale with thin-film sensors. Am. J. Physiol. 266:H2136-H2145, 1994.
7. Hofer, E., G. Mohr, G. Plank, and I. Schafferhofer. Electrical fields of anisotropic discontinuous cardiac conduction-An experimental approach. Biomed. Tech. 42:17-20, 1997.
8. Hooke, N., C. S. Henriquez, P. Lanzkron, and D. Rose. Linear algebraic transformations of the bidomain equations: Implications for numerical methods. Math. Biosci. 120:127-145, 1994.
9. Isomoto, S. et al. The influence of advancing age on the electrophysiological changes of the atrial muscle induced by programmed atrial stimulation. Jpn. Circ. J. 56:776-782, 1992.
10. Luo, C., and Y. Rudy. A model of the ventricular cardiac action potential. Depolarization and their interaction. Circ. Res. 68:1501-1526, 1991.
11. Maglaveras, N., J. M. T. de Bakker, F. J. L. van Capelle, C. Pappas, and M. J. Janse. Activation delay in healed myocardial infarction: A comparison between model and experiment. Am. J. Physiol. 269:H1441-H1449, 1995.
12. Mohr, G., E. Hofer, and G. Plank. A new real-time mapping system to detect microscopic cardiac excitation patterns. Biomed. Instrum. Technol. 33:455-461, 1999.
13. Pertsov, A. In: Discontinuous Conduction in the Heart, edited by P. M. Spooner, R. W. Joyner, and J. Jalife. Armonk: Futura, 1997, pp. 273-293.
14. Plank, G., and E. Hofer. Model study of vector-loop morphology during electrical mapping of microscopic conduction in cardiac tissue. Ann. Biomed. Eng. 28:1244-1252, 2000.
15. Plank, G., and E. Hofer. The use of cardiac electric near-field measurements to determine activation times. Ann. Biomed. Eng. 31:1076-1077, 2003.
16. Spach, M. S., and P. C. Dolber. Relating extracellular potentials and their derivatives to anisotropic propagation at microscopic level in human cardiac muscle: Evidence for electrical uncoupling of side-to-side fiber connections with increasing age. Circ. Res. 58:356-371, 1986.
17. Spooner, P. M., R. W. Joyner, and J. Jalife. Discontinuous Conduction in the Heart. Armonk: Futura, 1997.
18. Starobin, J. M., Y. I. Zilberter, E. M. Rusnak, and C. F. Starmer. Wavelet formation in excitable cardiac tissue: The role of wavefront-obstacle interactions in initiating high-frequency fibrillatory-like arrhythmias. Biophys. J. 70:581-594, 1996.
19. Suenson, M. Interaction between ventricular cells during the early part of excitation in the ferret heart. Acta Physiol. Scand. 125:81-90, 1985.