Effect of Atropine on Denervated Rabbit Ear Blood Vessels

Journal of Cardiovascular Pharmacology

Volumn 43, Issue 1, 2004, Pages 99-105

  Liu, Shu Qin ^a   Zang, Wei Jin ^a   Li, Zeng Li ^a   Yu, Xiao Jiang ^a   Li, Bao Ping ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Atropine; Denervation; Rabbit ear; Vasodilation

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ANISODAMINE; ANISODINE; ATROPINE; CHLORPROMAZINE; CHOLINERGIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BLOOD FLOW VELOCITY; BLOOD VESSEL WALL; CONTROLLED STUDY; DENERVATION; DRUG EFFECT; DRUG MECHANISM; EAR ARTERY; HEMORRHAGIC SHOCK; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; RABBIT; VASCULARIZATION;

ANIMALS; ATROPINE; DRUG INTERACTIONS; EAR; FEMALE; MALE; MUSCLE DENERVATION; MUSCLE, SMOOTH, VASCULAR; PARASYMPATHOLYTICS; RABBITS; RECEPTORS, ADRENERGIC, ALPHA; VASOCONSTRICTOR AGENTS;

EID: 0347594034     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200401000-00015     Document Type: Article

References (34)

1. Qian C, Xu XL, Cai TZ. Therapeutic action of a comprehensive cure in which atropine plays the major role on toxic bacillary dysentery. Zhonghua Yixue Zazhi. 1961;47:163-165. [article in Chinese]
2. Qian C, Cai TZ, Xu XL. The mechanisms and therapeutic effects of atropine on toxic bacillary dysentery. Zhonghua Erke Zazhi. 1964;13:363-366. [article in Chinese]
3. Zhu SH, Yan QY, Gao YS. The knowledge and treatment about fulminate epidemic meningococcal meningitis. Zhonghua Neike Zazhi. 1966;14:19-21. [article in Chinese]
4. Anonymous. Pharmacologic effects of anisodamine. From the Chinese Academy of Medical Sciences and Beijing Friendship Hospital. Clin Med J. 1975;1:133-138.
5. Anonymous. Changes in nail-fold microcirculation and amines in diseases manifesting acute microcirculatory disturbances. From the Chinese Academy of Medical and Beijing Friendship Hospital. Chin Med J. 1975;1:133-138.
6. Lin XR. Antishock drugs: vasodilating drugs. In: Song WX, Li Y, Sun YA, et al., eds. Practical Internal Medical Pharmacotherapeutics. Beijing: People's Medical Publishing House, 2000:255-259. [text in Chinese]
7. Li MT. Drugs acting on efferent nervous system: cholinoceptor blocking drugs. In: Chen RZ, Huang ZJ, eds. Therapeutic pharmacology: Beijing: People's Medical Publishing House, 2002;61-64. [text in Chinese]
8. Felderberg W, Sherwood SL. Injection of drugs into the lateral ventricle of the cat. J Physiol. 1954;123:148-167.
9. Haley TJ, McComic WG. Pharmacological effects produced by intracerebral injection of drugs in the conscious mouse. Br J Pharmacol. 1957;12:12-16.
10. Ostfeld AM, Argue A. Central nervous system effect of hyoscine in man. J. Pharmacol Exp Ther. 1962;137:133-139.
11. 3H-anisodamine. Acta Pharmaceutica. 1979;14:208-216. [article in Chinese]
12. Peng JZ, Jin LR, Chen XY, et al. Central effects of anisodamine, atropine, anisodine and scopolamine after intraventricular injection. Acta Pharmar Sinica. 1983;4:81-87. [article in Chinese]
13. Anonymous. Pharmacologic effects of anisodine compared with scopolamine. From the Chinese Academy of Medical Science. Honghua Yixue Zazhi. 1975;11:795-798.
14. Anonymous. Adsorption, distribution and excretion of anisodamine. From the Chinese Academy of Medical Science and Beijing Friendship Hospital. Chin Med J 1973;1:274-278. [English abstract].
15. Unna KR, Glaser K, Lipton E, et al. Dosage of drugs in infants and children. I. Atropine. Pediatrics. 1950;6:197-207.
16. Weiner N. Atropine, scopolamine, and related antimuscarinic drugs: atropine, scopolamine, and related belladonna alkaloids. In: Gihnan AG, Goodman LS, Gilman A, eds. Goodman and Gilman's the Pharmacological Basis of Therapeutics, 6th edition. New York: Macmillan, 1980:121-132.
17. Brown JH, Taylor P. Muscarinic agonists and antagonists. In: Hardman J, Limbird LE, Gilman AG, eds. Goodman and Gilman's the Pharmacological Basis of Therapeutics, 10th edition. New York: McGraw-Hill, 2001:162-171.
18. Bussel LJ. The relation of atropine to adrenaline and the sympathetic system. J Pharmal. 1940;69:128-139.
19. Luduena FP, Branin MJ. Adrenolytic activity of atropine, (t) - hyoscyamine, atroscine, homatropine, and related compounds. J Pharm Sci 1966;55:280-284.
20. Morris JL, Bevan RD. Proliferation of arteriovenous anastomoses in the developing rabbit ear is enhanced after denervation. Am J Anat. 1986;176:497-509.
21. Waterson JG, Smale DE. Location of noradrenergic structures in the central artery of the rabbit ear. Aust J Exp Biol Med Sci. 1976;45:301-308.
22. Lijima T, Tagawa T. Adrenergic and cholinergic innervation of the arteriovenous anastomoses in the rabbit's ear. Anal Rec. 1976;186:373-380.
23. Saville VL, Bumstock G. Use of reserpine and 6-Hydroxydopamine supports evidence for purinergic cotransmission in the rabbit ear artery. Eur J Pharmacol. 1988;155:271-277.
24. Saville VL, Maynard KI, Burnstock G. Neuropeptide Y potentiates purinergic as well as adrenergic responses of the rabbit ear artery. Eur J Pharmacol. 1990;176:117-125.
25. Feldberg W. The peripheral innervation of the vessel external ear of the rabbit. J Physiol. 1926;61:518-529.
26. Grant RT, Bland EF, Camp PD. Observations on the vessel and nerves of the rabbit's ear with special reference to the reaction to cold. Heart. 1932;16:69-101.
27. Steinsland OS, Furchgott RF. Vasoconstriction of the isolated rabbit ear artery caused by nicotine agonists acting on adrenergic neurons. J Pharmacol Exp Ther. 1975;193:128-137.
28. Manjeet S, Sim MK. Atropine-and scopolanmine-resistant subtypes of muscarinic receptors in the rabbit aorta. Eur J Pharmacol. 1989;174:99-165.
29. Barajas L, Wang P. Demonstration of acetylcholinesterase in the adrenergic nerves of the renal glomerular arterioles. J Ultrastruct Res. 1975;53:244-253.
30. Papka RE, Furness JB, Della NG, et al. Depletion by capsaicin of substance P-immunoreactivity and acetylcholinesterase activity from nerve fibers in the guinea pig heart. Neurosci Lett. 1981;27:47-54.
31. Maynard KI, Saville VL, Burnstock G, et al. Sensory-motor neuromodulation of sympathetic vasoconstriction in the rabbit central ear artery. Eur J Pharmacol. 1990;187:171-182.
32. Glick D, Glaubach S. The occurrence and distribution of atropinesterase and the specificity of atropinesterase. J Gen Physiol. 1941;25:197-205.
33. Drexler H. Factors involved in the maintenance of endothelial function. Am J Cardiol. 1998;82:35-45.
34. Rubanyi GM. The role of endothelium in cardiovascular homeostasis and disease. J Cardiovasc Pharmacol 1993;22:S1-S14.