Contribution of β-lactamase and PBP amino acid substitutions to amoxicillin/clavulanate resistance in β-lactamase-positive, amoxicillin/clavulanate-resistant Haemophilus influenzae

Journal of Antimicrobial Chemotherapy

Volumn 52, Issue 6, 2003, Pages 1018-1021

  Matic, Vlatka ^a,d   Bozdogan, Bülent ^a   Jacobs, Michael R ^b   Ubukata, Kimiko ^c   Appelbaum, Peter C ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c KITASATO UNIVERSITY   (Japan)

^d PLIVA CROATIA LTD   (Croatia)

Author keywords

lactamases; H. influenzae; Mutations; Penicillin binding proteins

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ARGININE; BETA LACTAMASE; CEFDINIR; CEFOTAXIME; LYSINE; PENICILLIN BINDING PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM TRANSFORMATION; CONTROLLED STUDY; GENE AMPLIFICATION; GENE MUTATION; GENETIC CODE; GENETIC SELECTION; GENETIC TRANSFORMATION; HAEMOPHILUS INFLUENZAE; JAPAN; NONHUMAN; PENICILLIN RESISTANCE; PROTEIN FUNCTION; PUBLISHING; SEQUENCE HOMOLOGY;

AMINO ACID SUBSTITUTION; AMOXICILLIN-POTASSIUM CLAVULANATE COMBINATION; BACTERIAL PROTEINS; BETA-LACTAMASES; CARRIER PROTEINS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; DRUG THERAPY, COMBINATION; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HEXOSYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; MUTATION; PENICILLIN-BINDING PROTEINS; PEPTIDYL TRANSFERASES; TRANSFORMATION, BACTERIAL;

EID: 0347519283     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg474     Document Type: Article

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