New [e]-Fused Caffeines: A Simple Synthesis of 3-Substituted [1,2,4]Triazolo[4,3-e]purines

Monatshefte fur Chemie

Volumn 134, Issue 4, 2003, Pages 565-571

  Mosselhi, Mosselhi A N ^a   Tawfik, Nagla M ^a   Shawali, Ahmad S ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

1,5 Electrocyclization; Caffeine; Hydrazines; Hydrazones

Indexed keywords

1,3,5 TRIMETHYL 2,4 DIOXO 8 (2 THIENYL) 1,2,3,4 TETRAHYDRO[1,2,4]TRIAZOLO[4,3 E]PURINE; 1,3,5 TRIMETHYL 2,4 DIOXO 8 (3 NITROPHENYL) 1,2,3,4 TETRAHYDRO[1,2,4]TETRAZOLO[4,3 E]PURINE; 1,3,5 TRIMETHYL 2,4 DIOXO 8 (4 BROMOPHENYL) 1,2,3,4 TETRAHYDRO[1,2,4]TRIAZOLO[4,3 E]PURINE; 1,3,5 TRIMETHYL 2,4 DIOXO 8 (4 CHLOROPHENYL) 1,2,3,4 TETRAHYDRO[1,2,4]TRIAZOLO[4,3 E]PURINE; 1,3,5 TRIMETHYL 2,4 DIOXO 8 (4 METHOXYPHENYL) 1,2,3,4 TETRAHYDRO[1,2,4]TRIAZOLO[4,3 E]PURINE; 1,3,5 TRIMETHYL 2,4 DIOXO 8 (4 METHYLPHENYL) 1,2,3,4 TETRAHYDRO[1,2,4]TRIAZOLO[4,3 E]PURINE; 1,3,5 TRIMETHYL 2,4 DIOXO 8 (4 NITROPHENYL) 1,2,3,4 TETRAHYDRO[1,2,4]TRIAZOLO[4,3 E]PURINE; 1,3,5 TRIMETHYL 2,4 DIOXO 8 PHENYL 1,2,3,4 TETRAHYDRO[1,2,4]TRIAZOLO[4,3 E]PURINE; ACETIC ACID; BROMINE; CAFFEINE DERIVATIVE; HYDRAZINE DERIVATIVE; PURINE DERIVATIVE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; METHODOLOGY; OXIDATION;

EID: 0347517566     PISSN: 00269247     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00706-002-0514-7     Document Type: Article

References (12)

1. Shawali AS, Mosselhi ANM, Tawfik NM (2001) J Org Chem 66: 4055
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3. b) Scammells PL, Baker SP, Belardinelli L, Olsson RA (1994) J Med Chem 37: 2704;
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5. For a review see: Shawali AS, Abdallah MA (1995) Advances in Heterocyclic Chemistry 63: 277 and references cited there
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7. Mosselhi MAN, Abbas IM (1993) Bull Pol Acad Sci 41: 179
8. Priewe H, Poljak A (1955) Chem Ber 88: 1932
9. a) Shawali AS (1993) Chem Rev 93: 2731;
10. b) Shawali AS (1983) Heterocycles 20: 2239;
11. c) Shawali AS, Parkanyi C (1980) J Heterocycl Chem 17: 833
12. For a review see: Broggini G, Molteni G, Zecchi G (1998) Heterocycles 47: 541 and references cited there