Improved DNA Flow Cytometric, DNA Ploidy, and S-phase Reproducibility between 15 Laboratories in Analysis of Breast Cancer Using Generalized Guidelines

Cytometry Part A

Volumn 56, Issue 1, 2003, Pages 1-7

  Baldetorp, Bo ^a   Bendahl, Pär Ola ^a   Fernö, Mårten ^a   Stål, Olle ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Breast cancer; DNA flow cytometry; DNA ploidy; Reproducibility; S phase fraction

Indexed keywords

ARTICLE; BREAST CANCER; CELL CYCLE S PHASE; CELL POPULATION; CELL SUSPENSION; CONTROLLED STUDY; DATA ANALYSIS; DNA FLOW CYTOMETRY; FLOW CYTOMETRY; HISTOGRAM; HUMAN; HUMAN CELL; LABORATORY; LABORATORY TEST; PLOIDY; PRACTICE GUIDELINE; PRIORITY JOURNAL; REPRODUCIBILITY; S PHASE FRACTION; STATISTICAL ANALYSIS;

EID: 0347504891     PISSN: 15524922     EISSN: None     Source Type: Journal    
DOI: 10.1002/cyto.a.10083     Document Type: Article

References (43)

1. Hedley DW, Clark GM, Cornelisse CJ, Killander D, Kute T, Merkel D. Consensus review of the clinical utility of DNA cytometry in carcinoma of the breast. Cytometry 1993;14:482-485.
2. Wenger CR, Clark GM. S-phase fraction and breast cancer: A decade of experience. Breast Cancer Res Treat 1998;51:255-265.
3. Bast RC Jr, Ravdin P, Hayes DF, Bates S, Fritsche H Jr, Jessup JM, Kemeny N, Locker GY, Mennel RG, Somerfield MR, for the American Society of Clinical Oncology Tumor Markers Expert Panel. 2000 Update recommendations for the use of tumor markers in breast cancer and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 2001;19:1865-1878.
4. Fitzgibbons PL, Page DL, Weaver D, Thor AD, Allred C, Clark GM, Ruby SG, O'Malley F, Simpson JF, Connolly JL, Hayes DF, Edge SB, Lichter A, Schnitt SJ. Prognostic factors in breast cancer. College of American Pathologists consensus statement 1999. Arch Pathol Lab Med 2000;124:966-978.
5. Wenger CR, Beardslee S, Owens MA, Pounds G, Oldaker T, Vendely P, Pandian MR, Harrington D, Clark GM, McGuire WL. DNA ploidy, S-phase, and steroid receptors in more than 127,000 breast cancer patients. Breast Cancer Res Treat 1993;28:9-20.
6. Sigurdsson H, Baldetorp B, Borg Å, Dalberg M, Fernö M, Killander D, Olsson H. Indicators of prognosis in node-negative breast cancer. N Engl J Med 1990;322:1045-1053.
7. Malmström P, Bendahl P-O, Boiesen P, Brünner N, Idvall I, Fernö M, for the South Sweden Breast Cancer Group. S-phase fraction and Urokinase plasminogen activator are better prognostic markers for distant recurrences than Nottingham prognostic index and histologic grade in a prospective study of premenopausal lymph node-negative breast cancer. J Clin Oncol 2001;19:2010-2019.
8. Stål O, Dufmats M, Hatschek T, Carstensen J, Klintenberg C, Rutqvist L-E, Skoog L, Sullivan S, Wingren S, Nordenskjöld B. S-phase fraction is a prognostic factor in stage I breast carcinoma. J Clin Oncol 1993;11:1717-1722.
9. Dressler LG, Seamer LC, Owens M, Clark GM, McGuire WL. DNA flow cytometry and prognostic factors in 1331 frozen breast cancer specimens. Cancer 1988;61:420-427.
10. Kallioniemi O-P, Hietanen T, Mattila J, Lehtinen M, Lauslahti K, Koivula T. Aneuploid DNA content and high S-phase fraction of tumour cells are related to poor prognosis in patients with primary, breast cancer. Eur J Cancer Clin Oncol 1987;23:277-282.
11. Clark GM, Dressler LG, Owens MA, Pounds G, Oldaker T, McGuire WL. Prediction of relapse or survival in patients with node-negative breast cancer by DNA flow cytometry. N Engl J Med 1989;320:627-633.
12. Harbeck N, Dettmar P, Thomssen C, Berger U, Ulm K, Kates R, Höfler H, Jänicke F, Graeff H, Schmitt M. Risk-group discrimination in node-negative breast cancer using invasion and proliferation markers: 6-year median follow-up. Br J Cancer 1999;80:419-426.
13. Chassevent A, Jourdan M-L, Romain S, Descotes F, Colonna M, Martin P-M, Bolla M, Spyratos F, for Multicenter Study Group PHRC95. S-phase fraction and DNA ploidy in 633 T1T2 breast cancers. A standardized flow cytometric study. Clin Cancer Res 2001;7:909-917.
14. Camplejohn RS, Ash CM, Gillet CE, Raikundalia B, Barnes DM, Gregory WM, Richards MA, Millis RR. The prognostic significance of DNA flow cytometry in breast cancer: results from 881 patients treated in a single centre. Br J Cancer 1995;71:140-145.
15. Merkel DE, Winchester DJ, Goldschmitt RA, August CZ, Wruck DM, Rademaker AW. DNA flow cytometry and pathologic grading as prognostic guides in axillary lymph node-negative breast cancer. Cancer 1993;72:1926-1932.
16. Meyer JS, Province MA. S-phase fraction and nuclear size in long term prognosis of patients with breast cancer. Cancer 1994;74:2287-2299.
17. Stanton PD, Cooke TG, Oakes SJ, Winstanley J, Holt S, George WD, Murray GD. Lack of prognostic significance of DNA ploidy and S phase fraction in breast cancer. Br J Cancer 1992;66:925-929.
18. Witzig TE, Ingle JN, Schaid DJ, Wold LE, Barlow JF, Gonchoroff NJ, Gerstner JB Krook JE, Grant CS, Katzmann JA. DNA ploidy and percent S-phase as prognostic factors in node-positive breast cancer: results from patients enrolled in two prospective randomized trials. J Clin Oncol 1993;11:351-359.
19. American Society of Clinical Oncology. Clinical guidelines for the use of tumor markers in breast cancer and colorectal cancer. J Clin Oncol 1996;14:2843-2877.
20. NCI-EORTC: 1st International Meeting on Cancer Diagnostics, Odense. From discovery to clinical practice: diagnostics innovation, implementation and evaluation. Int J Biol Markers 2000;15(S1).
21. NCI-EORTC: 2nd International Meeting on Cancer Diagnostics, Washington. From discovery to clinical practice: diagnostics innovation, implementation and evaluation. Int J Biol Markers 2002;17(S2).
22. Baldetorp B, Bendahl P-O, Fernö M, Alanen K, Delle U, Falkmer U, Hansson-Aggesjö B, Höckenström T, Lindgren A, Mossberg L, Nordling S, Sigurdsson H, Stål O, Visakorpi T. Reproducibility in DNA flow cytometric analysis of breast cancer: comparison of 12 laboratories results for 67 sample homogenates. Cytometry 1995;22:115-127.
23. D'hautcourt JL, Spyratos F, Chassevent A. Quality control study by the French Cytometry Association on flow cytometric DNA content and S-phase fraction (S%). Cytometry 1996;26:32-39.
24. Tirindelli DD, Spano M, Altavista P, Pantarotto M, Filippini C, Mazzini G, Erba E, Ubezio P. Quality control study of the Italian Group of Cytometry on flow cytometry DNA content measurements. II. Factors affecting inter- and intralaboratory variability. Cytometry 1997;30:85-97.
25. Ormerod MG, Tribukait B, Giaretti W. Consensus report of the task force on standardisation of DNA flow cytometry in clinical pathology. Analyt Cell Pathol 1998;17:103-110.
26. Chassevent A, Jourdan M-L, Ferrero-Pous M, Colonna M, Romain S, Spyratos F, Roth H, Bolla M. Standardization and quality control in the evaluation of proliferation parameters in T1T2, N0N1, M0 breast cancer: multicentric retrospective study II. DNA-ploidy and S-phase fraction. Bull Cancer 1999;86:685-691.
27. Duigou F, Herlin P, Marnay J, Michels JJ. Variation of flow cytometric DNA measurement in 1,485 primary breast carcinomas according to guidelines for DNA histogram interpretation. Cytometry 2000;42:35-42.
28. Vindelöv L, Christensen IJ, Nissen NI. Standardization of high-resolution flow cytometric DNA analysis by the simultaneous use of chicken and trout red blood cells as internal reference standards. Cytometry 1983;3:328-331.
29. Vindelöv L, Christensen IJ, Nissen NI. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 1983;3:323-327.
30. Thornthwaite JT, Sugarbaker EV, Temple WJ. Preparation of tissues for DNA flow cytometric analysis. Cytometry 1980;1:229-237.
31. Lee GM, Thornthwaite JT, Rasch EM. Picogram per cell determination of DNA by flow cytofluorometry. Anal Biochem 1984;137:221-226.
32. Krishan A. Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J Cell Biol 1975;66:188-193.
33. Hiddemann W, Schumann J, Andreeff M, Barlogie B, Herman CJ, Leif RC, Mayall BH, Murphy RF, Sandberg AA. Convention on nomenclature for DNA Cytometry. Cytometry 1984;5:445-446.
34. Baisch H, Gohde W, Linden WA. Analysis of PCP-data to determine the fraction of cells in various phases of the cell cycle. Radiat Environ Biophys 1975;12:31-39.
35. Altman DG. Practical statistics for medical research. London: Chapman & Hall; 1991. p 403-409.
36. Stål O, Wingren S, Carstensen J, Rutqvist LE, Skoog L, Klintenberg C, Nordenskjöld B. Prognostic value of DNA ploidy and S-phase fraction in relation to estrogen receptor content and clinicopathological variables in primary breast cancer. Eur J Cancer Clin Oncol 1989;25:301-309.
37. Beerman H, Kluin PhM, Hermans J, van de Velde CJH, Cornelisse CJ. Prognostic significance of DNA-ploidy in a series of 690 primary breast cancer patients. Int J Cancer 1990;45:34-39.
38. Coulson PB, Thornthwaite JT, Woolley TW, Sugarbaker EV, Seckinger D. Prognostic indicators including DNA histogram type, receptor content, and staging related to human breast cancer patient survival. Cancer Res 1984;44:4187-4196.
39. Fernö M, Baldetorp B, Borg Å, Olsson H, Sigurdsson H, Killander D. Flow cytometric DNA index and S-phase fraction in breast cancer in relation to other prognostic variables and in relation to clinical outcome. Acta Oncol 1992;31:157-165.
40. Balslev I, Christensen IB, Brunn Rasmussen B, Larsen JK, Lykkesfeldt AE, Thorpe SM, Rose C, Briand P, Mouridsen HT. Flow cytometric DNA ploidy defines patients with poor prognosis in node-negative breast cancer. Int J Cancer 1994;56:16-25.
41. Bagwell CB, Clark GM, Spyratos F, Chassevent A, Bendahl P-O, Stål O, Killander D, Jourdan ML, Romain S, Hunsberger B, Baldetorp B. Optimizing flow cytometric DNA ploidy and S-phase fraction as independent prognostic markers for node negative breast cancer specimens. Cytometry 2001;46:121-135.
42. Alvegård TA, Berg NO, Baldetorp B, Fernö M, Killander D, Ranstam J, Rydholm A, Åkerman M. Cellular DNA content and prognosis of high-grade soft tissue sarcoma. The Scandinavian Sarcoma Group Experience. J Clin Oncol 1990;8:538-547.
43. Stål O, Baldetorp B. S-phase fraction assessed by a variant of the rectangular model adapted to the flow-cytometric DNA histogram profile. Cytometry 1998;33:487-491.