A comparison of accurate mass techniques for the structural elucidation of fluconazole

Rapid Communications in Mass Spectrometry

Volumn 17, Issue 24, 2003, Pages 2804-2808

  Thompson, Christine M ^a   Richards, Donald S ^a   Fancy, Sally Ann ^a   Perkins, George L ^a   Pullen, Frank S ^a   Thom, Catriona ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DISSOCIATION; DRUG PRODUCTS; MASS SPECTROMETERS; MASS SPECTROMETRY;

ACCURATE MASS; COLLISIONALLY ACTIVATED DISSOCIATION; DRUG CANDIDATES; FLUCONAZOLE; MASS DATA; MOLECULAR FORMULAE; PRECURSOR IONS; RELATED SUBSTANCES; STRUCTURAL CHARACTERIZATION; STRUCTURAL ELUCIDATION;

ELECTROSPRAY IONIZATION;

FLUCONAZOLE;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; COMPARATIVE STUDY; DATA ANALYSIS; DIAGNOSTIC ACCURACY; DISSOCIATION; DRUG STRUCTURE; ELECTRON IONIZATION; ENERGY TRANSFER; EXCITATION; FOURIER TRANSFORM ION CYCLOTRON MASS SPECTROMETER; FOURIER TRANSFORMATION; INTERMETHOD COMPARISON; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; IONIZATION; MASS SPECTROMETRY; MATHEMATICAL ANALYSIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETER; STATISTICAL ANALYSIS; STRUCTURE ANALYSIS; SUSTAINED OFF RESONANCE COLLISIONALLY ACTIVATED DISSOCIATION SPECTRUM;

EID: 0347420015     PISSN: 09514198     EISSN: None     Source Type: Journal    
DOI: 10.1002/rcm.1270     Document Type: Article

References (10)

1. US Food and Drug Administration Centre for Drug Evaluation and Research. Guidelines for Submitting Samples and Analytical Data for Methods Validation, February, 1987.
2. Pramanik BN, Bartner PL, Chen G. Curr. Opin. Drug Discovery Develop. 1999; 2: 401.
3. Papac DI, Shahrokh Z. Pharm. Res. 2001; 18: 131.
4. McLafferty FW, Venkataraghavan R. Mass Spectral Correlations (2nd edn). American Chemical Society: Washington, DC, 1982.
5. Williams DH, Chem. Br. 1968; 4: 5.
6. Gabor B, Armstrong H. Anal. Chim. Acta 2003, 492: 105.
7. Smyth WF, McClean S, Ramachandran VN. Rapid Commun. Mass Spectrom. 2000; 14: 2061.
8. Burinsky DJ, Williams JD, Thornquest AD Jr, Sides SL. J. Am. Soc. Mass Spectrom. 2001; 12: 385.
9. Richardson K, Cooper K, Marriot MS, Tarbit MH, Troke PF, Whittle PJ. Spec. Publ-R. Soc. Chem. 1988; 65 (Top.Med.-Chem.): 255.
10. Harrison AG. Chemical Ionization Mass Spectrometry. CRC Press: Boca Raton, 1985.