Effect of the 807 C/T polymorphism in glycoprotein Ia on blood platelet reactivity

Journal of Biomedical Science

Volumn 10, Issue 6 II, 2003, Pages 731-737

  Luzak, Boguslawa ^a   Golanski, Jacek ^a   Rozalski, Marcin ^a   Watala, Cezary ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

Author keywords

Collagen receptors; GPIa polymorphisms; PFA 100 ; Platelet adhesion; Platelet inhibitors

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE DIPHOSPHATE; COLLAGEN; FIBRILLAR COLLAGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY GI9; THROMBIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 2;

ADULT; AGED; ALLELE; ANALYTIC METHOD; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE ADHESION; THROMBOCYTE FUNCTION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADULT; ANTIBODIES, MONOCLONAL; BLOOD PLATELETS; COLLAGEN; DNA PRIMERS; ELECTROPHORESIS; FEMALE; GLYCOPROTEINS; HUMANS; MALE; PLATELET ADHESIVENESS; POLAND; POLYMORPHISM, GENETIC; THROMBIN;

EID: 0347418249     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1159/000073960     Document Type: Article

References (40)

1. Alberio L, Dale GL. Review article: Platelet-collagen interactions: Membrane receptors and intracellular signalling pathways. Eur J Clin Invest 29:1066-1076;1999.
2. 1. Blood 89:1235-1242;1997.
3. Bellavite P, Andrioli G, Guzzo P, Arigliano P, Chirumblo S, Manzato F, Santonastaso C. A colorimetric method for the measurement of platelet adhesion in microtiter plates. Anal Biochem 216:444-450;1994.
4. Benze G, Heinrich J, Schulte H, Rust S, Nowak-Gottl U, Tataru MC, Kohler E, Assmann G, Junker R. Association of the GPIa C807T and GPIIIa PlA1/A2 polymorphisms with premature myocardial infarction in men. Eur Heart J 23:325-330;2002.
5. 1 might be a genetic risk factor for the development of stroke in younger patients. Blood 93:3583-3586;1999.
6. Clemetson KJ, Clemetson JM. Platelet collagen receptors. Thromb Haemost 86:189-197;2001.
7. 1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system. Blood 93:3578-3582;1999.
8. Furihata K, Nugent DJ, Kunicki TJ. Influence of platelet collagen receptor polymorphisms on risk for arterial thrombosis. Arch Pathol Lab Med 126:305-309;2002.
9. Gibbins JM, Okuma M, Farndale R, Barnes M, Watson SP. Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor γ-chain. FEBS Lett 413:255-259;1997.
10. Golanski J, Golanski R, Chizynski K, Iwaszkiewicz A, Rozalski M, Wieclawska B, Boncler M, Watala C. Platelet hyperreactivity after coronary artery bypass grafting: The possible relevance to glycoprotein polymorphisms. A preliminary report. Platelets 12:241-247;2001.
11. 1 in collagen-induced tyrosine phosphorylation in human platelets. Eur J Biochem 267:2088-2097;2000.
12. Higuchi R. Rapid, efficient DNA extraction for PCR from cells or blood. Perkin Elmer Cetus Amplifications 2:1-3;1989.
13. Jacquelin B, Rozenshteyn D, Kanaji S, Koziol JA, Nurden AT, Kunicki TJ. Characterization of inherited differences in transcription of the human integrin alpha 2 gene. J Biol Chem 276:23518-23524;2001.
14. 2 gene. Blood 97:1721-1726;2001.
15. Jung SM, Moroi M. Platelets interact with soluble and insoluble collagens through characteristically different reactions. J Biol Chem 273:14827-14837;1998.
16. Jung SM, Moroi M. Activation of the platelet collagen receptor integrin α(2)β(1): Its mechanism and participation in the physiological functions of platelets. Trends Cardiovasc Med 10:285-292;2000.
17. Jung SM, Moroi M. Signal-transducing mechanisms involved in activation of the platelet collagen receptor integrin α(2)β(1). J Biol Chem 275:8016-8026;2000.
18. 1 activation involves differential participation of ADP-receptor subtypes P2Y1 and P2Y12 but not intracellular calcium change. Eur J Biochem 268:3513-3522;2001.
19. 1 density. Blood 92:2382-2388;1998.
20. Kroll H, Gardemann A, Fechter A, Haberbosch W, Santoso S. The impact of the glycoprotein Ia collagen receptor subunit A1648G gene polymorphism on coronary artery disease and acute myocardial infarction. Thromb Haemost 83:392-396;2000.
21. Kundu SK, Heilmann EJ, Sio R, Garcia C, Davidson RM, Ostgaard RA. Description of an in vitro platelet function analyzer - PFA-100. Semin Thromb Hemost 21(suppl 2):106-112;1995.
22. Kunicki TJ. The influence of platelet collagen receptor polymorphisms in hemostasis and thrombotic disease. Arterioscler Thromb Vasc Biol 22:14-20;2002.
23. Kunicki TJ, Kritzik M, Annis DS, Nugent DJ. Hereditary variation in platelet integrin α 2 β 1 density is associated with two silent polymorphisms in the α 2 gene coding sequence. Blood 89:1939-1943;1997.
24. 1 integrin, a platelet receptor for collagen. Blood 95:1560-1564;2000.
25. Moroi M, Jung SM, Shinmyozu K, Tomiyama Y, Ordinas A, Diaz Ricart M. Analysis of platelet adhesion to a collagen-coated surface under flow conditions: The involvement of glycoprotein VI in the platelet adhesion. Blood 88:2081-2092;1996.
26. 1 integrin and GP VI. J Biol Chem 274:11897-11903;1999.
27. 1 integrin is essential for platelet interaction with collagen. EMBO J 20:2120-2130;2001.
28. Reiner AP, Aramaki KM, Teramura G, Gaur L. Analysis of platelet glycoprotein Ia (α 2 integrin) allele frequencies in three North American populations reveals genetic association between nucleotide 807 C/T and amino acid 505 Glu/Lys (HPA-5) dimorphisms. Thromb Haemost 80:449-456;1998.
29. Reiner AP, Kumar PN, Schwartz SM, Longstreth WT Jr, Pearce RM, Rosendaal FR, Psaty BM, Siscovick DS. Genetic variants of platelet glycoprotein receptors and risk of stroke in young women. Stroke 31:1628-1633;2000.
30. Roest M, Banga JD, Grobbee DE, de Groot PG, Sixma JJ, Tempelman MJ, van der Schouw YT. Homozygosity for 807 T polymorphism in α(2) subunit of platelet α(2)β(1) is associated with increased risk of cardiovascular mortality in high-risk women. Circulation 102: 1645-1650;2000.
31. 3 integrin. Eur J Pharmacol 454:1-8;2002.
32. Santoro SA, Zutter MM. The α 2 β 1 integrin. A collagen receptor on platelets and other cells. Thromb Haemost 74:813-821;1995.
33. Santoso S, Kunicki TJ, Kroll H, Haberbosch W, Gardemann A. Association of the platelet glycoprotein Ia C807T gene polymorphism with nonfatal myocardial infarction in younger patients. Blood 93:2449-2453;1999.
34. Savage B, Almus-Jacobs F, Ruggeri ZM. Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow. Cell 94:657-666;1998.
35. Savage B, Ginsberg MH, Ruggeri ZM. Influence of fibrillar collagen structure on the mechanisms of platelet thrombus formation under flow. Blood 94:2704-2715;1999.
36. Siljander P, Lassila R. Studies of adhesion-dependent platelet activation: Distinct roles for different participating receptors can be dissociated by proteolysis of collagen. Arterioscler Thromb Vasc Biol 19:3033-3043;1999.
37. Sixma JJ, van Zanten GH, Huizinga EG, van der Plas RM, Verkley M, Wu YP, Gros P, de Groot PG. Platelet adhesion to collagen: An update. Thromb Haemost 78:434-438;1997.
38. Sixma JJ, van Zanten GH, Saelman EU, Verkleij M, Lankhof H, Nieuwenhuis HK, de Groot PG. Platelet adhesion to collagen. Thromb Haemost 74:454-459;1995.
39. 1 and von Willebrand factor with specific sequences in native collagen is a requirement to resist shear forces. Blood 91:3808-3816;1998.
40. Watson S, Berlanga O, Best D, Frampton J. Update on collagen receptor interactions in platelets: Is the two-state model still valid? Platelets 11:252-258;2000.