Engagement of visual fixation suppresses sensory responsiveness and multisensory integration in the primate superior colliculus

European Journal of Neuroscience

Volumn 18, Issue 10, 2003, Pages 2867-2873

  Bell, A H ^a   Corneil, B D ^a   Munoz, D P ^a   Meredith, M A ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Auditory; Multisensory integration; Nonhuman primate; Superior colliculus; Visual; Visual fixation

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; AUDITORY ORIENTATION; BLINKING; CONTROLLED STUDY; EYE FIXATION; LATENT PERIOD; MALE; NONHUMAN; PRIMATE; PRIORITY JOURNAL; RHESUS MONKEY; SACCADIC EYE MOVEMENT; SUPERIOR COLLICULUS; VISUAL ORIENTATION;

ACOUSTIC STIMULATION; ACTION POTENTIALS; ANIMALS; AUDITORY PATHWAYS; BEHAVIOR, ANIMAL; BRAIN MAPPING; FIXATION, OCULAR; MACACA MULATTA; MALE; NEURONS; PHOTIC STIMULATION; REACTION TIME; SACCADES; SENSATION; SUPERIOR COLLICULUS; VISUAL PATHWAYS;

EID: 0347381401     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2003.02976.x     Document Type: Article

References (48)

1. Behan, M. & Kime, N.M. (1996) Intrinsic circuitry in the deep layers of the cat superior colliculus. Vis. Neurosci., 13, 1031-1042.
2. Bell, A.M., Corneil, B.D., Meredith, M.A. & Munoz, D.P. (2001) The influence of stimulus properties on multisensory processing in the awake primate superior colliculus. Can J. Exp. Psychol., 55, 123-132.
3. Bell, A.M., Corneil, B.D., Meredith, M.A., Van Opstal, A.J., Abrahams, V.C. & Munoz, D.P. (2000) Multisensory integration in the superior colliculus of the awake behaving primate. Soc. Neurosci. Abstr., 26, 1221.
4. Bender, D.B., Youakim, M. (2001) Effect of attentive fixation in macaque thalamus and cortex. J. Neurophysiol., 85, 219-234.
5. Corneil, B.D. & Munoz, D.P. (1996) The influence of auditory and visual distractors on human orienting gaze shifts. J. Neurosci., 16, 8193-8207.
6. Corneil, B.D., Van Wanrooij, M., Munoz, D.P. & Van Opstal, A.J. (2002) Auditory-visual interactions subserving goal-directed saccades in a complex Scene. J. Neurophysiol., 88, 438-454.
7. Crist, C.F., Yamasaki, D.S., Komatsu, H. & Wurtz, R.H. (1988) A grid system and a microsyringe for single cell recording. J. Neurosci. Meth., 26, 117-122.
8. Dorris, M.C., Paré, M. & Munoz, D.P. (1997) Neuronal activity in monkey superior colliculus related to the initiation of saccadic eye movements. J. Neurosci., 17, 8566-8579.
9. Driver, J. & Spence, C. (1998) Crossmodal attention. Curr. Opin. Neurobiol., 8, 245-253.
10. Edelman, J.A. & Keller, E.L. (1996) Activity of visuomotor burst neurons in the superior colliculus accompanying express saccades. J. Neurophysiol., 76, 908-926.
11. Everling, S., Dorris, M.C. & Munoz, D.P. (1998) Reflex suppression in the antisaccade task is dependent on prestimulus neural processes. J. Neurophysiol., 80, 1584-1589.
12. Frens, M.A. & Van Opstal, A.J. (1998) Visual-auditory interactions modulate saccade-related activity in monkey superior colliculus. Brain Res. Bull., 46, 211-224.
13. Groh, J.M. & Sparks, D.L. (1996) Saccades to somatosensory targets. II. motor convergence in primate superior colliculus. J. Neurophysiol., 75, 428-438.
14. Guitton, D. & Munoz, D.P. (1991) Control of orienting gaze shifts by the tectoreticulospinal system in the head-free cat. I. Identification, localization, and effects of behavior on sensory responses. J. Neurophysiol., 66, 1605-1623.
15. Hays, A.V., Richmond, B.J. & Optican, L.M.A. (1982) A UNIX-based multiple process system for real-time data acquisition and control. WESCON Conference Proceedings, 2, 1-10.
16. Hess, W.R., Burgi, S. & Bucher, V (1946) Motor function of tectal and tegmental area. Monatsschr. Psychiatr. Neurol., 112, 1-52.
17. Hikosaka, O. & Wurtz, R.H. (1983) Visual and oculomotor functions of monkey substantia nigra pars reticulata. II. Visual responses related to fixation of gaze. J. Neurophysiol., 49, 1254-1267.
18. Ingle, D. (1973) Selective choice between double prey objects by frogs. Brain Behav. Evol., 7, 127-144.
19. Jay, M.F. & Sparks, D.L. (1987) Sensorimotor integration in the primate superior colliculus. I. Motor convergence. J. Neurophysiol., 57, 22-34.
20. Jiang, W., Wallace, M.T., Jiang, H., Vaughan, J.W. & Stein, B.E. (2001) Two cortical areas mediate multisensory integration in superior colliculus neurons. J. Neurophysiol., 85, 506-522.
21. King, A.J. & Palmer, A.R. (1985) Integration of visual and auditory information in bimodal neurones in the guinea-pig superior colliculus. Exp. Brain Res., 60, 492-500.
22. Meredith, M.A. (1999) The frontal eye fields target multisensory neurons in cat superior colliculus. Exp. Brain Res., 128, 460-470.
23. Meredith, M.A., Nemitz, J.W. & Stein, B.E. (1987) Determinants of multi-sensory integration in superior colliculus neurons. I. Temporal factors. J. Neurosci., 7, 3215-3229.
24. Meredith, M.A. & Ramoa, A.S. (1998) Intrinsic circuitry of the superior colliculus: pharmacophysiological identification of horizontally oriented inhibitory interneurons. J. Neurophysiol., 79, 1597-1602.
25. Meredith, M.A. & Stein, B.E. (1983) Interactions among converging sensory inputs in the superior colliculus. Science, 221, 389-391.
26. Meredith, M.A. & Stein, B.E. (1985) Descending efferents from the superior colliculus relay integrated multisensory information. Science, 227, 657-659.
27. Meredith, M.A. & Stein, B.E. (1986) Visual, auditory, and somatosensory convergence on cells in superior colliculus results in multisensory integration. J. Neurophysiol., 56, 640-662.
28. Meredith, M.A., Wallace, M.T. & Stein, B.E. (1992) Visual, auditory and somatosensory convergence in output neurons of the cat superior colliculus: multisensory properties of the tecto-reticulo-spinal projection. Exp. Brain Res., 88, 181-186.
29. Mize, R.R., Jeon, C.J., Hamada, O.L. & Spencer, R.F. (1991) Organization of neurons labeled by antibodies to gamma-aminobutyric acid (GABA) in the superior colliculus of the Rhesus monkey. Vis. Neurosci., 6, 75-92.
30. Motter, B.C. & Mountcastle, V.B. (1981) The functional properties of the light-sensitive neurons of the posterior parietal cortex studied in waking monkeys: foveal sparing and opponent vector organization. J. Neurosci., 1, 3-26.
31. Munoz, D.P. & Corneil, B.D. (1995) Evidence for interactions between target selection and visual fixation for saccade generation in humans. Exp. Brain Res., 103, 168-173.
32. Munoz, D.P., Dorris, M.C., Paré, M. & Everling, S. (2000) On your mark, get set. Brainstem circuitry underlying saccade initiation. Can. J. Physiol. Pharmacol., 78, 934-944.
33. Munoz, D.P. & Fecteau, J.H. (2002) Vying for dominance: dynamic interactions control visual fixation and saccadic initiation in the superior colliculus. Prog. Brain Res., 140, 3-19.
34. Munoz, D.P. & Istvan, P.J. (1998) Lateral inhibitory interactions in the intermediate layers of the monkey superior colliculus. J. Neurophysiol., 79, 1193-1209.
35. Munoz, D.P. & Wurtz, R.H. (1993) Fixation cells in monkey superior colliculus. I. Characteristics of cell discharge. J. Neurophysiol., 70, 559-575.
36. Munoz, D.P. & Wurtz, R.H. (1995) Saccade-related activity in monkey superior colliculus, I. Characteristics of burst and buildup cells. J. Neurophysiol., 73, 2313-2333.
37. Populin, L.C. & Yin, T.C. (2002) Bimodal interactions in the superior colliculus of the behaving cat. J. Neurosci., 22, 2826-2834.
38. Segraves, M.A. & Goldberg, M.E. (1987) Functional properties of corticotectal neurons in the monkey's frontal eye field. J. Neurophysiol., 58, 1387-1419.
39. Sparks, D.L. (1978) Functional properties of neurons in the monkey superior colliculus: coupling of neuronal activity and saccade onset. Brain Res., 156, 1-16.
40. Sparks, D.L. (1986) Translation of sensory signals into commands for control of saccadic eye movements: role of primate superior colliculus. Physiol. Rev., 66, 118-171.
41. Stein, B.E. & Meredith, M.A. (1993) The Merging of the Senses. MIT, Cambridge, MA.
42. Stein, B.E., Meredith, M.A., Huneycutt, W.S. & McDade, L. (1989) Behavioral indices of multisensory integration: orientation to visual cues is affected by auditory stimuli. J. Cogn. Neurosci., 1, 12-24.
43. Thompson, K.G., Hanes, D.P., Bichot, N.P. & Schall, J.D. (1996) Perceptual and motor processing stages identified in the activity of macaque frontal eye field neurons during visual search. J. Neurophysiol., 76, 4040-4055.
44. Wallace, M.T., Meredith, M.A. & Stein, B.E. (1998) Multisensory integration in the superior colliculus of the alert cat. J. Neurophysiol., 80, 1006-1010.
45. Wallace, M.T., Wilkinson. L.K. & Stein, B.E. (1996) Representation and integration of multiple sensory inputs in primate superior colliculus. J. Neurophysiol., 76, 1246-1266.
46. Wurtz, R.H. & Goldberg, M.E. (1971) Superior colliculus cell responses related to eye movements in awake monkeys. Science, 171, 82-84.
47. Wurtz, R.H. & Hikosaka, O. (1986) Role of the basal ganglia in the initiation of saccadic eye movements. Prog. Brain Res., 64, 175-190.
48. Wurtz, R.H. & Mohler, C.W. (1976) Enhancement of visual responses in monkey striate cortex and frontal eye fields. J. Neurophysiol., 39, 766-772.