Molecular modeling of noncompetitive antagonists of the NMDA receptor: Proposal of a pharmacophore and a description of the interaction mode

Journal of Molecular Modeling

Volumn 8, Issue 2, 2002, Pages 65-72

  Elhallaoui, Menana ^a   Laguerre, Michel ^b   Carpy, Alain ^b   Ouazzani, Fouad Chahdi ^a  

^a SIDI MOHAMED BEN ABDELLAH UNIVERSITY   (Morocco)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Conformational analysis; MEP; MLP; NMDA receptor; Noncompetitive antagonists; Pharmacophore

Indexed keywords

DEXOXADROL; DIZOCILPINE; HEXYLAMINE; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NITROGEN; PHENYL GROUP;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; COMPUTER ANALYSIS; COMPUTER PROGRAM; CONFORMATION; CONTROLLED STUDY; ELECTRICITY; GEOMETRY; HYDROPHILICITY; LIPOPHILICITY; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULE; PHARMACOPHORE; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

BINDING SITES; DIOXOLANES; DIZOCILPINE MALEATE; ELECTROSTATICS; EXCITATORY AMINO ACID ANTAGONISTS; KETAMINE; LIPIDS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; N-METHYLASPARTATE; NITROGEN; PHENCYCLIDINE; PIPERIDINES; QUINOLINES; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0347368047     PISSN: 16102940     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00894-001-0067-4     Document Type: Article

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