CO2 Offgas as a Mechanistic Probe and Scale-up Tool in N-Acylations Using Mixed Anhydrides from Amino Acids and Isobutyl Chloroformate

Organic Process Research and Development

Volumn 7, Issue 6, 2003, Pages 888-895

  Chaudhary, Apurva ^a   Girgis, Michael J ^a   Prashad, Mahavir ^a   Hu, Bin ^a   Har, Denis ^a   Repič, Oljan ^a   Blacklock, Thomas J ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID ANHYDRIDE; AMINE; AMINO ACID; ANION; CARBON DIOXIDE; CARBOXYLIC ACID; CHLOROFORMIC ACID ISOBUTYL ESTER; FORMIC ACID DERIVATIVE; UNCLASSIFIED DRUG; URETHAN;

ACYLATION; ADDITION REACTION; ARTICLE; CHEMICAL REACTION; MECHANICAL PROBE; METHODOLOGY; QUANTITATIVE ANALYSIS; REACTION ANALYSIS;

EID: 0347365753     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op034085a     Document Type: Article

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