A Population-Based Case-Control Study of the Arg399Gln Polymorphism in DNA Repair Gene XRCC1 and Risk of Breast Cancer

Cancer Epidemiology Biomarkers and Prevention

Volumn 12, Issue 12, 2003, Pages 1462-1467

  Shu, Xiao Ou ^a,c   Cai, Qiuyin ^a   Gao, Yu Tang ^b   Wen, Wanqing ^a   Jin, Fan ^b   Zheng, Wei ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b SHANGHAI CANCER INSTITUTE   (China)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ESTROGEN; GENE PRODUCT; GENOMIC DNA; GLUTAMINE; SEX HORMONE BINDING GLOBULIN; UNCLASSIFIED DRUG; X RAY REPAIR CROSS COMPLEMENTING GROUP 1 PROTEIN;

ADULT; AGE; ALLELE; AMINO ACID SUBSTITUTION; ANTHROPOMETRY; ARTICLE; BODY MASS; BREAST CANCER; CANCER RISK; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; ESTROGEN BLOOD LEVEL; FEMALE; GENE; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MENSTRUATION; NUCLEOTIDE SEQUENCE; POPULATION RESEARCH; POSTMENOPAUSE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RISK FACTOR; X RAY REPAIR CROSS COMPLEMENTING GROUP 1 GENE;

ADULT; AGE DISTRIBUTION; AGED; ALLELES; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CHINA; CONFIDENCE INTERVALS; DNA REPAIR; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INCIDENCE; LOGISTIC MODELS; MIDDLE AGED; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POPULATION SURVEILLANCE; PROBABILITY; PROGNOSIS; REFERENCE VALUES; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SURVIVAL ANALYSIS;

EID: 0347363502     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Bertwistle, D., and Ashworth, A. Functions of the BRCA1 and BRCA2 genes. Curr. Opin. Genet. Dev., 8: 14-20, 1998.
2. Patel, R. K., Trivedi, A. H., Arora, D. C., Bhatavdekar, J. M., and Patel, D. D. DNA repair proficiency in breast cancer patients and their first-degree relatives. Int. J. Cancer, 73: 20-24. 1997.
3. Caldecott, K. W., Aoufouchi, S., Johnson, P., and Shall, S. XRCC1 polypeptide interacts with DNA polymerase β and possibly poly(ADP-ribose) polymerase, and DNA ligase III is a novel molecular "nick sensor" in vitro. Nucleic Acids Res., 24: 4387-4397, 1996.
4. Tebbs, R. S., Flannery, M. L., Meneses, J. J., Hartmann, A., Tucker, J. D., Thompson, L. H., Cleaver, J. E., and Pedersen, R. A. Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. Dev. Biol., 208: 513-529, 1999.
5. Shen, M. R., Zdzienicka, M. Z., Mohrenweiser, H., Thompson, L. H., and Thelen, M. P. Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA. Nucleic Acids Res., 26: 1032-1037, 1998.
6. Shen, M. R., Jones, I. M., and Mohrenweiser, H. Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. Cancer Res., 58: 604-608, 1998.
7. 1-DNA adducts and glycophorin A variant frequency. Cancer Res., 59: 2557-2561, 1999.
8. Matullo, G., Guarrera, S., Carturan, S., Peluso, M., Malaveille, C., Davico. L., Piazza, A., and Vineis, P. DNA repair gene polymorphisms, bulky DNA adducts in white blood cells and bladder cancer in a case-control study. Int. J. Cancer. 92: 562-567, 2001.
9. Abdel-Rahman, S. Z., Soliman, A. S., Bondy, M. L., Omar, S., El-Badawy, S. A., Khaled, H. M., Seifeldin, I. A., and Levin. B. Inheritance of the 194Trp and the 399Gln variant alleles of the DNA repair gene XRCC1 are associated with increased risk of early-onset colorectal carcinoma in Egypt. Cancer Lett., 159: 79-86, 2000.
10. Duell, E. J., Wiencke, J. K., Cheng, T. J., Varkonyi, A., Zuo, Z. F. S., Ashok, T. D., Mark, E. J., Wain, J. C., Christiani, D. C., and Kelsey, K. T. Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells. Carcinogenesis (Lond.), 21: 965-971, 2000.
11. Hu, J. J., Smith, T. R., Miller, M. S., Lohman, K., and Case, L. D. Genetic regulation of ionizing radiation sensitivity and breast cancer Risk. Environ. Mol. Mutagen., 39: 208-215, 2002.
12. 32P-DNA adducts in a sample of healthy subjects. Carcinogenesis (Lond.), 22: 1437-1445, 2001.
13. Gao, Y. T., Shu, X. O., Dai, Q., Potter, J. D., Brinton, L. A., Wen, W., Sellers, T. A., Kushi, L. H., Ruan, Z., Bostick, R. M., Jin, F., and Zheng, W. Association of menstrual and reproductive factors with breast cancer risk: results from the Shanghai Breast Cancer Study. Int. J. Cancer, 87: 295-300, 2000.
14. Goode, E. L., Ulrich, C. M., and Potter, J. D. Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol. Biomark. Prev., 11: 1513-1530, 2002.
15. Divine, K. K., Gilliland, F. D., Crowell, R. E., Stidley, C. A., Bocklage, T. J., Cook, D. L., and Belinsky, S. A. The XRCC1 399 glutamine allele is a risk factor for adenocarcinoma of the lung. Mutat. Res., 461: 273-278, 2001.
16. Park, J. Y., Lee, S. Y., Jeon, H. S., Bae, N. C., Chae, S. C., Joo, S., Kim, C. H., Park, J. H., Kam, S., Kim, I. S., and Jung, T. H. Polymorphism of the DNA repair gene XRCC1 and risk of primary lung cancer. Cancer Epidemiol. Biomark. Prev., 11: 23-27, 2002.
17. Zhou, W., Liu, G., Miller, D. P., Thurston, S. W., Xu, L. L., Wain, J. C., Lynch, T. J., Su, L., and Christiani, D. C. Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk. Cancer Epidemiol. Biomark. Prev., 12: 359-365, 2003.
18. Sturgis, E. M., Castillo, E. J., Li, L., Zheng, R., Eicher, S. A., Clayman, G. L., Strom, S. S., Spitz, M. R., and Wei, Q. Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck. Carcinogenesis (Lond.), 20: 2125-2129, 1999.
19. Shen, H., Xu, Y., Qian, Y., Yu, R., Qin, Y., Zhou, L., Wang, X., Spitz, M. R., and Wei, Q. Polymorphisms of the DNA repair gene XRCC1 and risk of gastric cancer in a Chinese population. Int. J. Cancer, 88: 601-606, 2000.
20. Stern, M. C., Umbach, D. M., van Gils, C. H., Lunn, R. M., and Taylor, J. A. DNA repair gene XRCC1 polymorphisms, smoking, and bladder cancer risk. Cancer Epidemiol. Biomark. Prev., 10: 125-131, 2001.
21. Lee, S. G., Kim, B., Choi, J., Kim, C., Lee, I., and Song, K. Genetic polymorphisms of XRCC1 and risk of gastric cancer. Cancer Lett., 187: 53-60, 2002.
22. Nelson, H. H., Kelsey, K. T., Mott, L. A., and Karagas, M. R. The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: evidence of gene-environment interaction. Cancer Res., 62: 152-155, 2002.
23. David-Beabes, G. L., and London, S. J. Genetic polymorphism of XRCC1 and lung cancer risk among African-Americans and Caucasians. Lung Cancer, 34: 333-339, 2001.
24. Butkiewicz, D., Rusin, M., Enewold, L., Shields, P. G., Chorazy, M., and Harris, C. C. Genetic polymorphisms in DNA repair genes and risk of lung cancer. Carcinogenesis (Lond.) 22: 593-597, 2001.
25. Ratnasinghe, D., Yao, S. X., Tangrea, J. A., Qiao, Y. L., Andersen, M. R., Barrett, M. J., Giffen, C. A., Erozan, Y., Tockman, M. S., and Taylor, P. R. Polymorphisms of the DNA repair gene XRCC1 and lung cancer risk. Cancer Epidemiol. Biomark. Prev., 10: 119-123, 2001.
26. Misra, R. R., Ratnasinghe, D., Tangrea, J. A., Virtamo, J., Andersen, M. R., Barrett, M., Taylor, P. R., and Albanes, D. Polymorphisms in the DNA repair genes XPD, XRCC1, XRCC3, and APE/ref-1, and the risk of lung cancer among male smokers in Finland. Cancer Lett., 191, 171-178, 2003.
27. Cavalieri, E., Frenkel, K., Liehr, J. G., Rogan, E., and Roy, D. Estrogens as endogenous genotoxic agents: DNA adducts and mutations. J. Natl. Cancer Inst. Monogr., 27: 75-93, 2000.
28. Liehr, J. G. Dual role of oestrogens as hormones and pro-carcinogens: tumour initiation by metabolic activation of oestrogens. Eur. J. Cancer Prev., 6: 3-10, 1997.
29. Duell, E. J., Millikan, R. C., Pittman, G. S., Winkel, S., Lunn, R. M., Tse, C. K. J., Eaton, A., Mohrenweiser, H. W., Newman, B., and Bell, D. A. Polymorphisms in the DNA repair gene XRCC1 and breast cancer. Cancer Epidemiol. Biomark. Prev., 10: 217-222, 2001.
30. Kim, S. U., Park, S. K., Yoo, K. Y., Yoon, K. S., Choi, J. Y., Seo, J. S., Park, W. Y., Kim, J. H., Noh, D. Y., Ahn, S. H., Choe, K. J., Strickland, P. T., Hirvonen, A., and Kang, D. XRCC1 genetic polymorphism and breast cancer risk. Pharmacogenetics, 12: 335-338, 2002.
31. Smith, T. R., Miller, M. S., Lohman, K., Lange, E. M., Case, L. D., Mohrenweiser, H. W., and Hu, J. J. Polymorphisms of XRCC1 and XRCC3 genes and susceptibility to breast cancer. Cancer Lett., 190: 183-190, 2003.