The Effect of Nevirapine on the Pharmacokinetics of Indinavir/Ritonavir 800/100 mg BID [1]

Journal of Acquired Immune Deficiency Syndromes

Volumn 35, Issue 1, 2004, Pages 97-98

  Burger, David M ^a   Prins, Jan M ^b   Van Der Ende, Marchina E ^c   Aarnoutse, Rob E ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EFAVIRENZ; INDINAVIR; NEVIRAPINE; RITONAVIR;

BLOOD SAMPLING; DATA ANALYSIS; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG MEGADOSE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LETTER; PRIORITY JOURNAL;

DRUG INTERACTIONS; HIV PROTEASE INHIBITORS; HUMANS; INDINAVIR; NEVIRAPINE; RITONAVIR;

EID: 0347360351     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00126334-200401010-00015     Document Type: Letter

References (6)

1. Piscitelli SC, Gallicano KD. Interactions among drugs for HIV and opportunistic infections. N Engl J Med. 2001;344:984-996.
2. Aarnoutse RE, Grintjes KJ, Telgt DS, et al. The influence of efavirenz on the pharmacokinetics of a twice-daily combination of indinavir and low-dose ritonavir in healthy volunteers. Clin Pharmacol Ther. 2002;71:57-67.
3. Moreno A, Casado JL, Marti-Belda P, et al. Concomitant use of non nucleoside reverse transcriptase inhibitors (NNRTI) does not decrease the inhibitory quotient of dual ritonavir/indinavir-based therapy. Paper presented at: 41th Interscience Conference on Antimicrobial Agents and Chemotherapy; December 14-18, 2001; Chicago. Abstract 1728.
4. Acosta EP, Kakuda TN, Brundage RC, et al. Pharmacodynamics of human immunodeficiency virus type I protease inhibitors. Clin Infect Dis. 2000;30(suppl 2):S151-S159.
5. Product information Kaletra. Chicago: Abbott; 2000.
6. Duval X, Le MV, Longuet C, et al. Efavirenz-induced decrease in plasma amprenavir levels in human immunodeficiency virus-infected patients and correction by ritonavir. Antimicrob Agents Chemother. 2000;44:2593.