Comparison of Franz cells and microdialysis for assessing salicylic acid penetration through human skin

International Journal of Pharmaceutics

Volumn 269, Issue 2, 2004, Pages 323-328

  Leveque, N ^a   Makki, S ^a   Hadgraft, J ^b   Humbert, Ph ^a  

^a UNIVERSITÉ DE FRANCHE COMTÉ   (France)

^b Medway University Campus ^*  (United Kingdom)

Author keywords

Franz cells; Human skin; Microdialysis; pH partition; Salicylic acid; Skin permeation

Indexed keywords

BUFFER; CELL RECEPTOR; PHOSPHATE; SALICYLIC ACID;

ABDOMEN; ADULT; ARTICLE; CELL TYPE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ABSORPTION; DRUG PENETRATION; DRUG SOLUBILITY; EXCISION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HYPOTHESIS; INTERMETHOD COMPARISON; MICRODIALYSIS; MONITORING; PH; PRIORITY JOURNAL; SAMPLE; SKIN ABSORPTION;

EID: 0347360190     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2003.09.012     Document Type: Article

References (16)

1. Ault J.M., Lunte C.E., Meltzer N.M., Riley C.M. Microdialysis sampling for the investigation. Pharm. Res. 9:1992;1256-1261.
2. Benfeldt E., Serup J., Menné T. Effect of barrier pertubation on cutaneous salicylic acid penetration in human skin: in vivo pharmacokinetics using microdialysis and non-invasive quantification of barrier perturbation. Br. J. Dermatol. 140:1999;739-748.
3. Bronaugh R.L., Stewart R.F., Simon M. Methods for in vitro percutaneous absorption studies VII: use of escised human kin. J. Pharm. Sci. 75:1986;1094-1097.
4. Franz T.J. Percutaneous absorption-on the relevance of in vitro data. J. Invest. Dermatol. 64:1975;190-195.
5. Harison S.M., Barry B.W., Dugard P.H. Effects of freezing on human skin permeability. J. Pharm. Pharmacol. 36:1984;261-262.
6. Le Quellec A., Dupin S., Genissel P., Saivin S., Marchand B., Houin J.P.M. Microdialysis probes calibration: gradient and tissue dependent changes in no net flux and reverse dialysis methods. J. Pharmacol. Toxicol. Methods. 33:1995;11-16.
7. Lonnroth P., Jasson P.A., Smith U. A microdialysis method allowing characterization of intracellular water space in humans. Am. J. Physiol. 253:1987;E228-E231.
8. Martin, A., Swarbrick, J., Cammarata, A., 1975. Physikalische Pharmazie. Wissenschaftliche Verlagsgesellscheft, Stuttgart, pp. 225-228.
9. Petersen, L.J., 1995. Skin microdialysis. In: Marks, R., Payne, A. (Eds.), Bioengineering and the Skin. CRC, Boca Raton, pp. 641-649.
10. Pirola R., Bareggi S.R., De Benedittis G. Determination of acetylsalicylic acid and salicylic acid in skin and plasma by high-performance liquid chromatography. J. Chromatogr. B. 705:1998;309-315.
11. Sartorelli P., Andersen H.R., Angerer J., Corish J., Drexler H., Göen T., Griffin P., Hotchkiss S.A.M., Larese F., Montomoli L., Perkins J., Schmelz M., Van de Sandt J., Williams F. Percutaneous penetration studies for risk assessment. Environ. Toxicol. Phar. 8:2000;133-152.
12. Schaefer H., Loth H. An ex vivo model for the study of drug penetration into human skin. Pharm. Res. 13:1996;366.
13. Schnetz E., Fartasch M. Microdialysis for the evaluation of penetration through the human skin barrier - a promising tool for the future research? Eur. J. Pharam. Sci. 12:2001;165-174.
14. Smith J.C., Irwin W.J. Ionisation and the effect of absorption enhancers on transport of salicylic acid through silastic rubber and human skin. Int. J. Pharm. 210:2000;69H-82H.
15. Vermeer B.J., Reman F.C., Van Gent C.M. The determination of lipids and proteins in suction blister fluid. J. Invest. Dermatol. 64:1975;190-195.
16. Wagner H., Kostka K.H., Lehr C.M., Schaefer U.F. Drug distribution in human skin using two different in vitro test systems: comparison with in vivo data. Pharm. Res. 17:2000;1475-1481.