Insulin-exacerbated hypertension in captopril-treated spontaneously hypertensive rats: Role of sympathoexcitation

Canadian Journal of Physiology and Pharmacology

Volumn 81, Issue 11, 2003, Pages 1036-1041

  Roysommuti, Sanya ^a,b   Mozaffari, Mahmood S ^a,c   Wyss, J Micheal ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b KHON KAEN UNIVERSITY   (Thailand)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Blood pressure; Captorpil; Clonidine; Hexamethonium; Insulin; Rat

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CAPTOPRIL; CLONIDINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GANGLION BLOCKING AGENT; HEXAMETHONIUM; INSULIN;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; HEART RATE; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SPONTANEOUSLY HYPERTENSIVE RAT; STATISTICAL SIGNIFICANCE;

ADRENERGIC FIBERS; ANIMALS; BLOOD PRESSURE; CAPTOPRIL; FEMALE; HEART RATE; HYPERTENSION; INSULIN; MALE; PREGNANCY; RATS; RATS, INBRED SHR;

EID: 0347360101     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y03-095     Document Type: Article

References (29)

1. Brands, M.W., Garrity, C.A., Holman, M.G., and Hall, J.E. 1994. Exaggerated pressor and chronotropic response to chronic hyperinsulinemia in SH versus WKY rats. Am. J. Hypertens. 7: 75-81.
2. Brands, M.W., Harrison, D.L., Keen, H.L., Gardner, A., Shek, E.W., and Hall, I.E. 1997. Insulin-induced hypertension in rats depends on an intact renin-angiotensin system. Hypertension, 29(4): 1014-1019.
3. Bunag, R.D., Tomita, T., and Sasaki, S. 1983. Chronic sucrose ingestion induces mild hypertension and tachycardia in rats. Hypertension, 5(2): 218-225.
4. Bunag, R.D., Krizsan-Agbas, D., and Itoh, H. 1991. Sympathetic activation by chronic insulin treatment in conscious rats. J. Pharmacol. Exp. Ther. 259(1): 131-138.
5. Campbell, W.B., and Zimmer, J.A. 1980. Insulin-induced renin release: blockade by indomethacin in the rat. Clin. Sci. 58(5): 415-418.
6. Endre, T., Mattiasson, I., Berglund, G., and Hulthen, U.L. 1994. Insulin and renal sodium retention in hypertension-prone men. Hypertension, 23(3): 313-319.
7. Fang, T.C., and Huang, W.C. 1998a. Role of angiotensin II in hyperinsulinemia-induced hypertension in rats. J. Hypertension, 16(12 Pt. 1): 1767-1774.
8. Fang, T.C., and Huang, W.C. 1998b. Angiotensin receptor blockade blunts hyperinsulinemia-induced hypertension in rats. Hypertension, 32(2): 235-242.
9. Huang, W.C., Fang, T.C., and Cheng, J.T. 1998. Renal denervation prevents and reverses hyperinsulinemia-induced hypertension in rats. Hypertension, 32: 249-254.
10. Hwang, I.S., Ho, H., Hoffman, B.B., and Reaven, G.M. 1987. Fructose-induced insulin resistance and hypertension in rats. Hypertension, 10(5): 512-516.
11. Iimura, O., Shimamoto, K., Matsuda, K., Masuda, A., Takizawa, H., Higashiura, K., Miyazaki, Y., Hirata, A., Ura, N., and Nakagawa, M. 1995. Effects of angiotensin receptor antagonist and angiotensin converting enzyme inhibitor on insulin sensitivity in fructose-fed hypertensive rats and essential hypertensives. Am. J. Hypertension, 8: 353-357.
12. Iyer, S.N., and Katovich, M.J. 1994. Effect of chronic losartan potassium treatment on fructose-induced hypertension. Life Sci. 55(7): PL139-PL144.
13. Kitamura, S., Seto, S., Nagao, S., Matsuo, K., Akahoshi, M., and Yano, K. 1994. Chronic hyperinsulinemia augments deoxycorticosterone acetate-salt hypertension. Hypertension, 23(Suppl. I): I-16-I-19.
14. Landsberg L. 1996. Insulin sensitivity in the pathogenesis of hypertension and hypertensive complications. Clint. Expert. Hypertension, 18(3 & 4): 337-346.
15. Lopez-Sela, P., Brime, J.I., Diaz, F., Marin, B., Costales, M., and Vijande, M. 1989. Effects of inhibitors of the renin-angiotensin system on water intake after insulin administration. Appetite, 13(2): 143-154.
16. Moreau, P., Lamarche, L., Laflamme, A.K., Calderone, A., Yamaguchi, N., and de Champlain, J. 1995. Chronic hyperinsulinaemia and hypertension: the role of the sympathetic nervous system. J. Hypertension, 13: 333-340.
17. Morgan, D.A., Balon, T.W., Ginsberg, B.H., and Mark, A.L. 1993. Nonuniform regional sympathetic nerve responses to hyperinsulinemia in rats. Am. J. Physiol. 264(2 Pt. 2): R423-R427.
18. Mozaffari, M.S., Roysommuti, S., and Wyss, J.M. 1996. Contribution of the sympathetic nervous system to hypertensive response to insulin excess in spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 27: 539-544.
19. Mozaffari, M.S., Roysommuti, S., and Wyss, J.M. 1997. Renal function in spontaneously hypertensive rats with insulin-exacerbated hypertension. Clin. Exp. Hypertens. 19(3): 313-329.
20. Passa, P. 1992. Hyperinsulinemia, insulin resistance and essential hypertension. Horm. Res. 38: 33-38.
21. Raasch, W., Bartels, T., Gieselberg, A., Dendorfer, A., and Dominiak, P. 2002. Angiotensin I-converting enzyme inhibition increases cardiac catecholamine content and reduces mono-amine oxidase activity via an angiotensin type 1 receptor-mediated mechanism. J. Pharm. Exp. Therap. 300(2): 428-434.
22. The Diabetes Prevention Program Research Group. 2002. Hypertension, insulin, and proinsulin in participants with impaired glucose tolerance. Hypertension, 40: 679-686.
23. Westfall, D.P. 1997. Antihypertensive drugs. In Modern pharmacology. Edited by C.R. Craig and R.E. Stitzel. Little Brown and Company (Inc.), Boston, Mass. pp. 235-252.
24. Wiedmann, P., de Courten, M., and Bohlen, L. 1993. Insulin resistance, hyperinsulinemia and hypertension. J. Hypertens. 11(Suppl. 5): S27-S38.
25. Wu, J.N., and Berecek, K.H. 1993. Prevention of genetic hypertension by early treatment of spontaneously hypertensive rats with the angiotensin converting enzyme inhibitor captopril. Hypertension, 22(2): 139-146.
26. Wyss, J.M. 2003. Central nervous system in arterial pressure regulation. In Hypertension Primer. 3rd ed. Edited by J.L. Izzo and H.R. Black. Lippincott, New York, pp 99-102.
27. Wyss, J.M., and Carlson S.H. 2001. The contribution of the autonomic nervous system to the development of hypertension. Curr. Hypertens. Rep. 3: 255-263.
28. Wyss, J.M., Roysommuti, S., King, K., Kadisha, I., Regan, C.P., and Berecek, K.H. 1994. Salt-induced hypertension in normotensive spontaneously hypertensive rats. Hypertension, 23(6 Pt. 1): 791-796.
29. Wyss, J.M., Mozaffari, M.S., and Roysommuti, S. 1995. Contribution of the sympathetic nervous system to salt-sensitivity in lifetime captopril treated spontaneously hypertensive rats. J. Hypertens. 13(9): 1037-1042.