Prospective randomised treatment with recombinant human growth hormone in cystic fibrosis

Archives of Disease in Childhood

Volumn 88, Issue 12, 2003, Pages 1078-1081

  Schibler, A ^a,b   Von Der Heiden, R ^b   Birrer, P ^b   Mullis, P E ^b  

^a MATER CHILDREN S HOSPITAL   (Australia)

^b UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT GROWTH HORMONE;

ADOLESCENT; ADULT; AIRWAY RESISTANCE; ARTICLE; BICYCLE ERGOMETER; BODY COMPOSITION; CLINICAL ARTICLE; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG SCREENING; DUAL ENERGY X RAY ABSORPTIOMETRY; EXERCISE; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; LEAN BODY WEIGHT; LUNG FUNCTION; MALE; MEASUREMENT; PRIORITY JOURNAL; SCHOOL CHILD; STATISTICAL SIGNIFICANCE; WEIGHT;

ADOLESCENT; ADULT; BODY MASS INDEX; CHILD; CYSTIC FIBROSIS; EXERCISE TOLERANCE; FEMALE; FOLLOW-UP STUDIES; FORCED EXPIRATORY VOLUME; GROWTH HORMONE; HUMANS; MALE; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; RESPIRATORY SYSTEM AGENTS; TREATMENT OUTCOME; VITAL CAPACITY;

EID: 0347320554     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.88.12.1078     Document Type: Article

References (33)

1. Kraemer R, Ruedeberg A, Hadorn B, et al. Relative underweight in cystic fibrosis and its prognostic value. Acta Paediatr Scand 1978;67:33-7.
2. Nixon PA, Orenstein DM, Kelsey SF, et al. The prognostic value of exercise testing in patients with cystic fibrosis. N Engl J Med 1992;327:1785-8.
3. Heijerman HG. Chronic obstructive lung disease and respiratory muscle function: the role of nutrition and exercise training in cystic fibrosis. Respir Med 1993;87(suppl B):49-51.
4. Hanning RM, Blimkie CJ, Bar-Or O, et al. Relationships among nutritional status and skeletal and respiratory muscle function in cystic fibrosis: does early dietary supplementation make a difference? Am J Clin Nutr 1993;57:580-7.
5. Tayek JA, Brasel JA. Growth hormone administration decreases urea nitrogen losses in malnourished cancer patients. Clin Res 1992;40:95a.
6. Ward HC, Halliday D, Sim AJW. Protein and energy metabolism with biosynthetic human growth hormone after gastrointestinal surgery. Ann Surg 1987;206:56-61.
7. Jiang ZM, He GZ, Zhang SY. Low-dose growth hormone and hypocaloric nutrition attenuates the protein-catabolic response after major operation. Ann Surg 1989;10:513-24.
8. Ziegler TR, Young JS, Ferrari-Baliviera E, et al. Use of humane growth hormone combined with nutritional support in a critical care unit. J Parenter Enteral Nutr 1990;14:574-81.
9. Grünfeld C, Feingold KR. Metabolic disturbances and wasting in the acquired immunodeficiency syndrome. N Engl J Med 1992;327:329-37.
10. Gregory JW, Greene SA, Jung RT, et al. Changes in body composition and energy expenditure after six weeks' growth hormone treatment. Arch Dis Child 1991;66:598-602.
11. Wernerman J. Effect of growth hormone on muscle and protein in critically ill patients. Acta Endocrinol 1993;128(suppl 2):19-22.
12. Mulligan K, Grunfeld C, Hellerstein MK, et al. Anabolic effects of recombinant human growth hormone in patients with wasting associated with human immunodeficiency virus infection. Clin Endocrinol Metab 1993;77:956-62.
13. Schambelan M, Mulligan K, Grünfeld C, et al. Recombinant human growth hormone in patients with HIV-associated wasting. A randomized, placebo-controlled trial. Serostim Study Group. Ann Intern Med 1996;125:873-82.
14. Burdet L, de Muralt B, Schutz Y, et al. Administration of growth hormone to underweight patients with chronic obstructive pulmonary disease. A prospective, randomized, controlled study. Am J Respir Crit Care Med 1997;156:1800-6.
15. Suchner U, Rothkopf M, Stanislaus G, et al. Growth hormone and pulmonary disease. Arch Intern Med 1990;150:1225-30.
16. Sackey AH, Taylor CJ, Barraclough M. Growth hormone as a nutritional adjunct in cystic fibrosis: results of a pilot study. J Hum Nutr Dietet 1995;8:185-91.
17. Huseman CA, Colombo JL, Brooks MA, et al. Anabolic effect of biosynthetic growth hormone in cystic fibrosis patients. Pediatr Pulmonol 1996;22:90-5.
18. Hardin DS, Sly JP. Effects of growth hormone treatment in children with cystic fibrosis: The National Cooperative Study experience. J Pediatr 1997;131:S65-9.
19. Kraemer R, Rüdeberg A, Kläy M, et al. Relationship between clinical conditions, radiographic findings and pulmonary functions in patients with cystic fibrosis. Helv Paediatr Acta 1979;34:417-28.
20. Zapletal A, Samanek M, Paul T. Progress in respiration research. Basel: Karger, 1987.
21. Conconi F, Ferrari M, Ziglio PG, et al. Determination of the anaerobic threshold by a noninvasive field test in runners. J Appl Physiol 1982;50:869-73.
22. Probst H, Comminot C, Rojas J. Conconi test on the bicycle ergometer. Schweiz Z Sportmed 1989;37:141-7.
23. Chrispin AR, Norman AP. The system evaluation of the chest. Radiography in cystic fibrosis. Pediatr Radiol 1974;2:101-6.
24. Prader A, Largo RH, Molinari L, et al. Physical growth of Swiss children from birth to 20 years of life. Helv Paediatr Acta Suppl 1989;52:1-125.
25. Salomon F, Cuneo R, Hesp R, et al. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 1989;321:1797-803.
26. Cuneo R, Salomon F, Wiles C, et al. Growth hormone treatment in growth hormone-deficient adults. I. Effects on muscle mass and strength. J Appl Physiol 1991;70:688-94.
27. Cuneo R, Salomon F, Wiles C, et al. Growth hormone treatment in growth hormone-deficient adults. II. Effects on exercise performance. J App Physiol 1991;70:695-700.
28. Bengtsson BA, Brummer RJ, Bosaeus I. Growth hormone and body composition. Horm Res 1990;33(suppl 4):19-24.
29. Bengtsson BA, Johannson G, Shalet SM, et al. Treatment of growth hormone deficiency in adults. J Clin Endocrinol Metab 2000;85:933-42.
30. Carrel AI, Allen DB. Effects of growth hormone on body composition and bone metabolism. Endocrine 2000;12:163-72.
31. Lange KH, Isaksson F, Juul A, et al. Growth hormone enhances effects of endurance training on oxidative muscle metabolism in elderly woman. Am J Physiol Endocrinol Metab 2000;279:E989-96.
32. Gibbs GE, Bostick WL. Incomplete pancreatic deficiency in cystic fibrosis of the pancreas. J Pediatr 1950;37:3320-5.
33. Kerem E, Reisman J, Corey M, et al. Prediction of mortality in patients with cystic fibrosis. N Engl J Med 1992;326:1187-91.