Age-dependent effect of limb immobilization and remobilization on rat bone

Folia Biologica

Volumn 50, Issue 3-4, 2002, Pages 121-127

  Trȩbacz, Hanna ^a   Dmowska, Mirosława ^b   Baj, Jacek ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^b MARIA CURIE SK ODOWSKA UNIVERSITY   (Poland)

Author keywords

Apparent density; Bone mineralization; Immobilization; Remobilization; Serum

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; PHOSPHORUS;

AGE; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MINERALIZATION; BONE TURNOVER; CALCIUM BLOOD LEVEL; CONTROLLED STUDY; IMMOBILIZATION; MALE; NONHUMAN; PHOSPHATE BLOOD LEVEL; RAT;

ADAPTATION, PHYSIOLOGICAL; AGING; ANIMALS; BODY WEIGHT; BONE AND BONES; BONE DENSITY; FEMUR; IMMOBILIZATION; MALE; MOTOR ACTIVITY; PELVIS; RATS;

ANIMALIA;

EID: 0347297583     PISSN: 00155497     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. ASHMAN R. B., COWIN S. C., VAN BUSKIRK W. C., RICE J. C. 1984. A continuous wave technique for the measurement of the elastic properties of cortical bone. J. Biomechanics 17: 349-361.
2. ASHMAN R. B., RHO J. Y., TURNER C. H. 1989. Anatomical variation of orthotropic elastic moduli of the proximal human tibia. J. Biomechanics 22: 895-900.
3. CHEN M. M., JEE W. S. S., KE H. Z., LIN B. Y., LI Q. N., LI X. J. 1992. Adaptation of cancellous bone to aging and immobilization in growing rats. Anat. Rec. 234: 317-334.
4. DEHORITY W., HALLORAN B. P., BIKLE D. D., CURREN T., KOSTENIUK P. J., WRONSKI T. J., SHEN Y., RABKIN B., BOURAOUI A., MOREY-HOLTONE. 1999. Bone and hormonal changes induced by skeletal unloading in the mature male rat. Amer. J. Physiol. 276 (Endocrinol. Metab. 39): E62-E69.
5. FROST H. M. 1990. Skeletal structural adaptation to mechanical usage (SATMU): 2. Redefining Wolff's Law: the remodeling problem. Anat. Rec. 226: 414-422.
6. GRYNPAS M. D., ACITO A., DIMITRIU M., MERTZ B. P., VERY J. M. 1992. Changes in bone mineralization, architecture and mechanical properties due to long-term (1 year) administration of pamidronate (APD) to adult dogs. Osteoporosis Int. 2: 74-81.
7. HALLORAN B. P., BIKLE D. D., HARRIS J., FOSKETT H. C., MOREY-HOLTON E. 1993. Skeletal unloading decreases production of 1,25-dihydroxyvitamin D. Amer. J. Physiol. 64 (Endocrinol. Metab. 27): E712-E716.
8. HAN S. M., SZARZANOWICZ T. E., ZIV I. 1998. Effect of ovariectomy and calcium deficiency on the ultrasound velocity, mineral density and strength in the rat femur. Clinical Biomechanics 13: 480-484.
9. IJIRI K., MA Y. F., JEE W. S., AKAMINE T., LIANG X. 1995. Adaptation of non-growing former epiphysis and metaphyseal trabecular bones to aging and immobilization in rat. Bone 17(4 Suppl): 207S-212S.
10. INMAN C. L., WARREN G. L., HOGAN H. A., BLOOMFIELD S. A. 1999. Mechanical loading attenuates bone loss due to immobilization and calcium deficiency. J. Appl. Physiol. 87: 189-195.
11. JEE W. S. S., MA Y. F., LI, X. J. 1997. Immobilized adult cancellous bone site in a growing rat as an animal model of human osteoporosis. J. Histotechnol. 20: 1-5.
12. KANEPS A. J., STOVER S. M., LANE N. E. 1997. Changes in canine cortical and cancellous bone mechanical properties following immobilization and remobilization with exercise. Bone 21: 419-423.
13. KANNUS P., JARVINEN T. L. N., SIEVANEN H., KVIST M., RAUHANIEMI J., MAUNU V.-M., HURME T., JOZSA L., JARVINEN M. 1996. Effects of immobilization, three forms of remobilization, and subsequent deconditioning on bone mineral content and density in rat femora. J. Bone Min. Res. 11: 1339-11346.
14. LI X. J., JEE W. S. S., CHOW S.-Y., WOODBURY D. M. 1990. Adaptation of cancellous bone to aging and immobilization in the rat: A single photon absorptiometry and histomorphpmetry study. Anat. Rec. 227: 12-24.
15. LI X. J., JEE, W. S. S. 1991. Adaptation of diaphyseal structure to aging and decreased mechanical loading in the adult rat: A densitometric and histomorphometric study. Anat. Rec. 229: 12-24.
16. MAEDA H., KIMMEL D. B., RAAB D. M., LANE N. E. 1993. Muscoskeletal recovery following hindlimb immobilization in adult female rats. Bone 14: 152-159.
17. MARTIN R. B. 1990. Effects of simulated weightlessness on bone properties in rats. J. Biomechanics 23: 1021-1029.
18. MARTIN R. B., BOARDMAN D. L. 1993. The effect of collagen fiber orientation, porosity, density and mineralization on bovine cortical bone bending properties. J. Biomechanics 26: 1047-1054.
19. MATSUMOTO T., NAKAYAMA K., KODAMA Y., FUSE H., NAKAMURA T., FUKUMOTO S. 1998. Effect of mechanical unloading and reloading on periosteal bone formation and gene expression in tail-suspended rapidly growing rats. Bone 22(5 Suppl.): 89S-93S.
20. MOREY-HOLTON E. R., GLOBUS R. K. 1998. Hindlimb unloading of growing rats: a model for predicting skeletal changes during space flight. Bone 22(5 Suppl.): 83S-88S.
21. TRȨBACZ H., BAJ J. 1999. Effect of immobilization on physical properties of femurs in growing rats. Polish J. Med. Phys. & Eng. 5: 141-147.
22. TUUKKANEN J., PENG Z., VAANANEN K. 1992. The effect of training on the recovery from immobilization-induced bone loss in rats. Acta Physiol. Scand. 145: 407-411.
23. VAN BUSKIRK W. C., COWIN S. C., WARD R. N. 1981. Ultrasonic measurement of orthotropic elastic constants of bovine femoral bone. J. Biomech. Eng. 103: 67-72.