Mechanisms underlying combined action of clonidine and local anesthetics

Bulletin of Experimental Biology and Medicine

Volumn 136, Issue 1, 2003, Pages 53-55

  Ponomarev, V P ^a   Galenko Yaroshevskii, A P ^a   Dukhanin, A S ^b   Anisimova, V A ^c  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^b PIROGOV RUSSIAN NATIONAL RESEARCH MEDICAL UNIVERSITY   (Russian Federation)

^c SOUTHERN FEDERAL UNIVERSITY   (Russian Federation)

Author keywords

2 adrenoceptors; Clonidine; Human platelets; Imidazoline receptors; Local anesthetics

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2A ADRENERGIC RECEPTOR; CLONIDINE; IMIDAZOBENZIMIDAZOLE DERIVATIVE; IMIDAZOLINE RECEPTOR; LOCAL ANESTHETIC AGENT; RU 1117; TETRACAINE; TRICAINE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; HUMAN; HUMAN TISSUE; PHARMACODYNAMICS; THROMBOCYTE; THROMBOCYTE AGGREGATION;

ADENOSINE DIPHOSPHATE; ADRENERGIC ALPHA-AGONISTS; ANESTHETICS, LOCAL; BENZIMIDAZOLES; BLOOD PLATELETS; CLONIDINE; HUMANS; INHIBITORY CONCENTRATION 50; PLATELET AGGREGATION; PROTEIN BINDING; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, DRUG; TETRACAINE; TIME FACTORS;

EID: 0347269017     PISSN: 00074888     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026088813307     Document Type: Article

References (8)

1. V. V. Ponomarev, N. B. Pererva, and A. P. Galenko-Yaroshevskii, Byull. Eksp. Biol. Med., Suppl. 3, 68-72 (2002).
2. V. V. Ponomarev, A. P. Galenko-Yaroshevskii, and A. S. Dukhanin, Ibid., 135, No. 6, 669-671 (2003).
3. P. R. Ernsberg, R. Giuliano, R. N. Willette, et al., Hypertension, 54, No. 2, 554-557 (1988).
4. C. A. Fairbanks, L. S. Stone, K. F. Kitto, et al., Pharmacol. Exp. Ther., 300, No. 1, 282-290 (2002).
5. Z. P. Khan, C. N. Ferguson, and R. M. Jones, Anaesthesia, 54, No. 2, 146-165 (1999).
6. McSPI-Europe Research Group, Anesthesiology, 54, 346-363 (1997).
7. J. Petrusewica and R. Kaliszan, Gen. Pharmacol., 54, 819-823 (1991).
8. R. B. Su, J. Li, K. Gao, et al., Acta Pharmacol. Sin., 21, No. 11, 1011-1015 (2000).