Dose-dependent biodistribution of [99mTc]DTPA-mannosyl-dextran for breast cancer sentinel lymph node mapping

Nuclear Medicine and Biology

Volumn 30, Issue 8, 2003, Pages 805-810

  Ellner, Scott J ^a,b   Hoh, Carl K ^b,c   Vera, David R ^b,c   Darrah, Denise D ^b   Schulteis, Gery ^d   Wallace, Anne M ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d University of California   (United States)

Author keywords

Breast cancer; Lymphoseek; Radiopharmaceutical; Sentinel lymph node; 99mTc DTPA mannosyl dextran

Indexed keywords

LYMPHOSEEK; PENTETATE TECHNETIUM MANNOSYL DEXTRAN TC 99M; RADIOPHARMACEUTICAL AGENT; TECHNETIUM SULFUR COLLOID TC 99M; UNCLASSIFIED DRUG;

ADULT; AGED; ASSAY; BREAST CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG MONITORING; DRUG SAFETY; FEMALE; HUMAN; HUMAN TISSUE; INJECTION SITE; LYMPH NODE BIOPSY; RADIATION ABSORPTION; RADIOACTIVITY; SENTINEL LYMPH NODE; SIDE EFFECT; STATISTICAL SIGNIFICANCE;

EID: 0347224282     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2003.10.001     Document Type: Conference Paper

References (15)

1. Jemal A., Murray T., Samuels A., Ghafoor A., Ward E., Thun M. Cancer statistics. Cancer J Clin. 53:2003;5-25.
2. Tabar L., Duffy S.W., Vitak B., Chen H.H., Prevost T.C. The natural history of breast carcinoma what have we learned from screening? Cancer. 86:1999;449-462.
3. Chua B., Ung O., Taylor R., Bilous M., Salisbury E., Boyages J. Treatment implications of a positive sentinel lymph node biopsy for patients with early-stage breast carcinoma. Cancer. 92:2001;1769-1774.
4. Krag D., Weaver J.C.Alex, Fairbank J.T. Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Surg Oncol. 2:1993;335-339.
5. Mariani G., Moresco L., Viale G., Villa G., Bagnasco M., Canavese G. Radioguided sentinel lymph node biopsy in breast cancer surgery. J Nucl Med. 42:2001;1198-1215.
6. 99mTc]DTPA-mannosyl- dextran . J Nucl Med. 42:2001;951-959.
7. Vera D.R., Wisner E.R., Stadalnik R.C. Sentinel node imaging via a nonparticulate receptor-binding radiotracer. J Nucl Med. 38:1997;530-535.
8. Steer C.J. Receptor-mediated endocytosis mechanisms, biologic function, and molecular propeties . Zakim D., Boyer T.D. Hepatology. A Textbook of Liver Disease. 3rd ed :1996;149-214 W.B. Saunders, Philadelphia.
9. Wallace A.M., Hoh C.K., Vera D.R., Darrah D., Schulteis G. Lymphoseek A molecular radiopharmceutical for sentinel node detection . Ann Surg Oncol. 10:2003;531-538.
10. 99mTc]DPTA-mannosyl-dextran. Nucl Med Biol. 30:2003;457-464.
11. Hung J.C., Wiseman G.A., Wahner H.W., Mullan B.P., Taggart T.R., Dunn W.L. Filtered technetium-99m-sulfur colloid evaluated for lymphoscintigraphy. J Nucl Med. 36:1995;1895-1901.
12. Stabin M.G. MIRDOSE personal computer software for internal dose assessment in nuclear medicine . J Nucl Med. 37:1996;538-546.
13. Recommendations of the International Commission on Radiological Protection, 1990. 1991;International Committee on Radiological Protection, New York.
14. Snyder, WS, Ford, MR, Warner, GG, Watson, SB. "S" absorbed dose per unit cumulative activity for selected radionuclides and organs. In: MIRD Pamphlet No. 11. New York: The Society of Nuclear Medicine; 1975. p. 92-93.
15. Waddington W.A., Keshtgar M.R.S., Taylor I., Lakhani S.R., Short M.D., Ell P.J. Radiation safety of the sentinel lymph node technique in breast cancer. Eur J Nucl Med. 27:2000;377-391.