Transcriptional Analysis of Product-Concentration Driven Changes in Cellular Programs of Recombinant Clostridium acetobutylicum Strains

Biotechnology and Bioengineering

Volumn 84, Issue 7, 2003, Pages 842-854

  Tummala, Seshu B ^a,b   Junne, Stefan G ^a,c   Paredes, Carlos J ^a   Papoutsakis, Eleftherios T ^a  

^a Northwestern University   (United States)

^b ABBOTT LABORATORIES   (United States)

^c TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

AAD; AdhE1; Clostridia; CoAT; DNA microarray; Ethanol; Hierarchical clustering; Metabolic engineering; Metabolic flux analysis; Microenvironment; Operon annotation; Self organizing maps; SOMS

Indexed keywords

ALCOHOLS; ALDEHYDES; BIOSYNTHESIS; DNA; ENZYMES; METABOLISM; RNA;

GENE EXPRESSION;

BIOTECHNOLOGY;

ACETONE; ALCOHOL; ALDEHYDE DEHYDROGENASE; BUTANOL; COENZYME A TRANSFERASE; COMPLEMENTARY RNA;

BACTERIAL STRAIN; CLOSTRIDIUM ACETOBUTYLICUM; CLUSTER ANALYSIS; DNA MICROARRAY; DOWN REGULATION; FATTY ACID SYNTHESIS; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; METABOLIC ENGINEERING; MICROENVIRONMENT; NONHUMAN; OPERON; REVIEW;

ADAPTATION, PHYSIOLOGICAL; CLOSTRIDIUM; COMPUTER SIMULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RECOMBINANT PROTEINS; SPECIES SPECIFICITY; TRANSCRIPTION, GENETIC;

CLOSTRIDIA; CLOSTRIDIUM ACETOBUTYLICUM;

EID: 0347132481     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.10851     Document Type: Review

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