Mepivacaine for Spinal Anesthesia in Parturients Undergoing Elective Cesarean Delivery: Maternal and Neonatal Plasma Concentrations and Neonatal Outcome

Zentralblatt fur Gynakologie

Volumn 125, Issue 12, 2003, Pages 518-521

  Bremerich, D H ^a,d   Schlosser R L ^b   L'Allemand, N ^a   Brandes, R P ^c   Ahr, A ^d   Piorko, D ^a   Kaufmann, M ^d   Kessler, P ^a  

^a Klinik für Anästhesiologie   (Germany)

^b Abteilung für Neonatologie   (Germany)

^c Inst Kardiovaskulare Physiol   (Germany)

^d UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Analgesia; Analgesics; Anesthesia; Cesarean delivery; Fentanyl; Intrathecal; Local anesthetics; Mepivacaine; Obstetrics; Opioids; Pharmacology; Spinal anesthesia

Indexed keywords

BUPIVACAINE; FENTANYL; LOCAL ANESTHETIC AGENT; MEPIVACAINE; OPIATE;

ADULT; ANESTHESIA INDUCTION; APGAR SCORE; ARTICLE; BLOOD; CESAREAN SECTION; CHEMISTRY; CHILDBIRTH; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; ELECTIVE SURGERY; FEMALE; FETOMATERNAL TRANSFUSION; FETUS BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MATERNAL PLASMA; METHODOLOGY; NEWBORN; OPERATION DURATION; OUTCOMES RESEARCH; POSTOPERATIVE ANALGESIA; PREGNANCY; SPINAL ANESTHESIA; SURGICAL TECHNIQUE; TIME; UMBILICAL CORD BLOOD; UMBILICAL VEIN;

ANESTHESIA, SPINAL; ANESTHETICS, LOCAL; APGAR SCORE; CESAREAN SECTION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; FENTANYL; FETAL BLOOD; HUMANS; INFANT, NEWBORN; MATERNAL-FETAL EXCHANGE; MEPIVACAINE; PREGNANCY; SURGICAL PROCEDURES, ELECTIVE; TIME FACTORS; UMBILICAL VEINS;

EID: 0347132466     PISSN: 00444197     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-44817     Document Type: Article

References (21)

1. Abboud TK, Moore MJ, Jacobs J, Murakawa K, Soraya M, Zhu J. Epidural mepivacaine for cesarean section. Maternal and neonatal effects. Regional Anesth 1987; 12: 76-79
2. Adams HA, Biscoping J, Ludolf K, Börgmann A, Bachmann-Mennenga B, Hempelmann G. The quantitative analysis of amide local anesthetics using high pressure liquid chromatography and ultraviolet detection (HPLC/UV). Reg Anaesth 1989; 12: 53-57
3. Amiel-Tison C, Barrier G, Shnider SM, Levinson G, Hughes SC, Stefani SJ. A new neurologic and adaptive capacity scoring system for evaluating obstetric medications in full-term newborns. Anesthesiology 1982; 56: 340-350
4. Aouad MT, Siddik SS, Jalbout MI, Baraka AS. Does pregnancy protect against intrathecal lidocaine-induced transient neurologic symptoms? Anesth Analg 2001; 92: 401-404
5. Ben-David B, Miller G, Gavriel R, Gurevitch A. Low-dose bupivacaine-fentanyl spinal anesthesia for cesarean delivery. Reg Anesth Pain Med 2000; 25: 235-239
6. Bromage PR, Burfoot MF, Ceowell DE. Quality of epidural blockade. I. Influence of physical factors. Br J Anaesth 1964; 36: 342-352
7. Brown WU Jr, Bell GC, Lurie AO, Weiss JB, Scanlon JW, Alper MH. Newborn blood levels of lidocaine and mepivacaine in the first postnatal day following maternal epidural anesthesia. Anesthesiology 1975; 42: 698-707
8. Burns SM, Cowan CM, Wilkes RG. Prevention and management of hypotension during spinal anaesthesia for elective Caesarean section: a survey of practice. Anaesthesia 2001; 56: 794-798
9. Clark RB, Jones GL, Barclay DL, Greifenstein FE, McAninch PE. Maternal and neonatal effects of 1% and 2% mepivacaine for lumbar extradural analgesia. Br J Anaesth 1975; 47: 1283-1289
10. Dahlgren G, Hultstrand C, Jakobsson J, Norman M, Eriksson EW, Martin H. Intrathecal sufentanil, fentanyl, or placebo added to bupivacaine for Cesarean section. Anesth Analg 1997; 85: 1288-1293
11. Federici D, Lacelli B, Agarossi A, Cipolla L, Conti M. Cesarean section using the Misgav Ladach method. Int J Gynaecol Obstet 1997; 57: 273-279
12. Hunt CO, Naulty JS, Bader AM, Hauch MA, Vartikar JV, Datta S, Hertwig LM, Ostheimer GW. Perioperative analgesia with subarachnoid fentanyl-bupivacaine for cesarean delivery. Anesthesiology 1989; 71: 535-540
13. Khaw KS, Ngan Kee WD, Wong M, Ng F, Lee A. Spinal ropivacaine for cesarean delivery: a comparison of hyperbaric and plain solutions. Anesth Analg 2002; 94: 680-685
14. Køhler F, Sorensen JF, Helbo-Hansen HS. Effect of delayed supine positioning after induction of spinal anaesthesia for caesarean section. Acta Anaesthesiol Scand 2002; 46: 441-446
15. Meininger D, Byhahn C, Kessler P, Nordmeyer J, Alparslan Y, Hall BA, Bremerich DH. Intrathecal fentanyl, sufentanil, or placebo combined with hyperbaric mepivacaine 2% for parturients undergoing elective cesarean delivery. Anesth Analg 2003; 96: 852-858
16. Meuser T, Eichler F, Grond S, Winkler B, Lehmann KA. Anesthesia for cesarean section in Germany. A survey. Anaesthesist 1998; 47: 557-564
17. Morishima HO, Daniel SS, Finster M, Poppers PJ, James LS. Transmission of mepivacaine hydrochloride (Carbocaine) across the human placenta. Anesthesiology 1966; 27: 147-154
18. Rorarius M, Suominen P, Haanpaa M, Puura A, Baer G, Pajunen P, Tuimala R. Neurologic sequelae after caesarean section. Acta Anaesthesiol Scand 2001; 45: 34-41
19. Salazar F, Bogdanovich A, Adalia R, Chabas E, Gomar C. Transient neurologic symptoms after spinal anaesthesia using isobaric 2% mepivacaine and isobaric 2% lidocaine. Acta Anaesthesiol Scand 2001; 45: 240-245
20. Scanlon JW, Brown WU, Weiss JB, Alper MH. Neurobehavioral responses of newborn infants after maternal epidural anesthesia. Anesthesiology 1974; 40: 121-128
21. Singh H, Yang J, Thornton K, Giesecke AH. Intrathecal fentanyl prolongs sensory bupivacaine spinal block. Can J Anaesth 1995; 42: 987-991