Computer models of depolarization alterations induced by myocardial ischemia: The effect of superimposed ischemic inhomogeneities on propagation in space and time-frequency domains

Journal of Biological Systems

Volumn 7, Issue 4, 1999, Pages 553-574

  Shenai, Mahesh ^a   Gramatikov, Boris ^a   Thakor, Nitish V ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cardiac modeling; Cellular networks; Depolarization; Myocardial ischemia; Time frequency analysis

Indexed keywords

EID: 0347121886     PISSN: 02183390     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0218339099000322     Document Type: Article

References (40)

1. Abboud S., Detection of transient myocardial ischemia by computer analysis of standard and signal-averaged high-frequency ECG in patients undergoing percutaneous transluminal coronary angioplasty, Circulation 76 (1987) pp. 585-596.
2. Abboud S., Subite alterations in the high-frequency QRS potentials during myocardial ischemia in dogs, Computers and Biomedical Research 20 (1987) pp. 384-395.
3. Abboud S., O. Berenfeld and D. Sadeh, Simulation of high-resolution QRS complex using a ventricular model with a fractal conduction system. Effects of ischemia on high-frequency QRS potentials, Circulation Res. 68 (1991) pp. 1751-1760.
4. Abboud S., J. Leor, and M. Eldar, High frequency ECG during reperfusion therapy of acute myocardial infarction, Computers in Cardiology, 1990, pp. 351-353.
5. Aversano T. et al., High-frequency QRS electrocardiography in the detection of reperfusion following thrombolytic therapy, Clinical Cardiology 17 (1994) pp. 175-182.
6. Barr R. and R. Plonsey, Propagation of excitation in idealized anisotropic two-dimensional tissue, Biophys. J. 45 (1984) pp. 1191-1202.
7. Beeler G. and H. Reuter, Reconstruction of the action potential of ventricular myocardial fibers, J. Physiol. 268 (1976) pp. 177-210.
8. + current, Circ Res. 79 (1996) pp. 208-221.
9. Ferrero J. et al., Propagation of Action potentials in cardiac acute regional ischemia: A computer simulation study, Computers in Cardiology (1997).
10. Gettes L. and C. We, Effect of acute ischemia on cardiac electrophysiology, in the heart and cardiovascular system, ed. by H. Fozzard et al. (Raven Press, New York, 1992) pp. 2021-2054.
11. Gramatikov B., Detection of late potentials in the signal averaged ECG combining time and frequency domain analysis, Medical & Biological Engineering & Computing 31 (1993) pp. 333-339.
12. Holschneider M., Localization properties of wavelet transforms, J. Math. Phys. 34 (1993) pp. 3227-3244.
13. Janse M. and A. Wit, Electrophysiological mechanisms of ventricular arrythmias resulting from myocardial ischemia and infarction, Phys. Rev. 69 (1989) pp. 1049-1152.
14. Johnson T. et al., Magnitude and time course of extracellular potassium inhomogeneities during acute ischemia in pigs, Circulation 83 (1991) pp. 622-634.
15. Kagiyama Y., J. Hill and L. Gettes, Interaction of acidosis and increased extracellular potassium on action potential and conduction in guinea pig ventricular muscle, Circ. Res. 61 (1982) pp. 614-623.
16. Kaiser G., A friendly guide to wavelets (Boston: Basel, Berlin: Birkhauser, 1994).
17. Kleber A. et al., Changes in conduction velocity during acute ischemia in ventricular myocardium of isolated porcine heart, Circulation 73 (1986) pp. 189-198.
18. Kodama I. et al., Combined effects of hypoxia, hyperkalemia, and acidosis on membrane action potential and excitability of guinea-pig ventricular cells, J. Mol. Cell Cardiol. 16 (1984) pp. 247-259.
19. Kronland-Martinet R., J. Morlet and A. Grossmann, Analysis of sound patterns through wavelet transforms, Int. J. Pattern Recognition and Artificial Intelligence 1 (1987) pp. 273-302.
20. Lander P., Abnormal intra-QRS potentials as a senstive marker of ischemically altered vetricular activation, PACE 19 (1996) p. 573.
21. Luo C., A dynamic model of the cardiac ventricular action potential: II. Afterdepolarizations, triggered activity, and potentiation, Circ. Res. 74 (1994) pp. 1097-1113.
22. Luo C. and Y. Rudy, A model of the ventricular cardiac action potential: Depolarization, repolarization, and their interaction, Circ. Res. 68 (1991) pp. 1501-1526.
23. Luo C. and Y. Rudy, A dynamic model of the cardiac ventricular action potential: I. Simulations of ionic currents and concentrations, Circ. Res. 74 (1994) pp. 1071-1086.
24. Malmivuo J. and R. Plonsey, Bioelectromagnetism (Oxford University Press, New York, 1995).
25. Mei D. and G. Gross, Evidence for the involvement of the ATP-sensitive potassium channel in a novel model of hypoxic preconditioning in dogs, Cardiovasc Res. 30 (1995) pp. 222-230.
26. Mirvis, D., Anatomic basis for the injury current producing ST-segment shifts on the body surface ECG, J. Electrocardiology 24 (Supplement) (1992) pp. 41-43.
27. Mor-Avi V. et al., Coronary occlusion on high-frequency content of the epicardial electrograms and body surface electrocardiogram, Circulation 76 (1987) pp. 737-748.
28. Okajima M., T. Kawaguchi and S. Suzuki, Detection of higher frequency components at mid-QRS stage of the electrocardiogram, Computers in Cardiology (1990).
29. Pettersson J., Changes in high-frequency QRS components during prolonged coronary artery occlusion in humans, J. Electrocardiol. 28 (Suppl) (1995) pp. 225-257.
30. Pettersson J. et al., Electrocardiographic changes during prolonged coronary artery occlusion in man: comparison of standard and high-frequency recordings, Clinical Physiology 18 (1998) pp. 179-186.
31. Preda I. et al., QRS alterations in body surface potential distributions during percutaneous transluminal coronary angioplasty in single vessel discase, J. Electrocardiography 27 (1994) pp. 311-22.
32. Roberge F., A. Vinet and B. Victorri, Reconstruction of propagated electrical activity with a two-dimensional model of anisotropic heart muscle, Clin. Res. 68 (1986) pp. 461-175.
33. Roberts D., L. Hersh and A. Scher, Influence of cardiac fiber orientation on wavefront voltage conduction velocity and tissue resistivity in the dog, Circ. Res. 44 (1979) pp. 701-712.
34. Roberts D. and A. Scher, Effect of tissue anisotropy on extracellular potential fields in canine myocardium in situ, Circ. Res. 60 (1982) pp. 342-351.
35. Roth B., How the anisotropy of the intracellular and extracellular conductivities influences stimulation of cardiac muscle, J. Math. Bio. 30 (1992) pp. 633-646.
36. Sato R. et al., Effects of intracellular acidification on membrane currents in ventricular cells of the guinea pig, Circ. Res. 57 (1985) pp. 553-561.
37. Shaw R. and Y. Rudy, Electrophysiologic effects of acute myocardial ischemia: A mechanistic investigation of action potential conduction and conduction failure, Circ. Res. 80 (1997) pp. 124-138.
38. Shaw R. and Y. Rudy, Electrophysiologic effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration, Cardiovascular Res. (1997).
39. + loss, REduction in REpolarization time, and tissue ATP levels during myocardial hypoxia and ischemia, Circ. Res. 72 (1993) pp. 560-570.
40. Yantani A., A. Brown and N. Akaike, Effect of extracellular pH on sodium current in isolated, single rat ventricular, J. Membrane Biol. 78 (1984) pp. 163-168.