Neurobehavioral teratogenicity in antiepileptic drugs: The new Pandora's box

Neurology

Volumn 62, Issue 1, 2004, Pages 8-9

  Duchowny, Michael ^a  

^a MIAMI CHILDREN'S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; PHENYTOIN; VALPROIC ACID;

BEHAVIOR DISORDER; BEHAVIOR TERATOLOGY; COGNITIVE DEFECT; COMORBIDITY; CONGENITAL MALFORMATION; DEVELOPMENTAL DISORDER; DOSE RESPONSE; EDITORIAL; EDUCATION; EPILEPSY; EVIDENCE BASED MEDICINE; FACE DYSMORPHIA; FEMALE; FETAL HYDANTOIN SYNDROME; FETUS MALFORMATION; HUMAN; INTELLIGENCE; INTELLIGENCE QUOTIENT; LONG TERM CARE; MATERNAL DISEASE; MENTAL DEFICIENCY; MONOTHERAPY; NEURAL TUBE DEFECT; OUTCOMES RESEARCH; PREGNANCY; PREGNANCY DISORDER; PRENATAL CARE; PRENATAL DRUG EXPOSURE; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK BENEFIT ANALYSIS; SEIZURE; SOCIAL STATUS; TERATOGENICITY;

EID: 0347092045     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.62.1.8     Document Type: Editorial

References (6)

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2. Kaneko S, Battino D, Andermann E, et al. Congenital malformations due to antiepileptic drugs. Epilepsy Res 1999;33:145-158.
3. Samren BE, van Duijn CM, Koch S, et al. Maternal use of antiepileptic drugs and the risk of major congenital malformations: a joint European prospective study of human teratogenesis associated with maternal epilepsy. Epilepsia 1997;38:981-990.
4. Shapiro S, Slone D, Hartz C, et al. Anticonvulsants and parental epilepsy in the development of birth defects. Lancet 1976;i:272-275.
5. Adab N, Jacoby A, Smith D, Chawick D. Additional educational needs in children born to mothers with epilepsy. J Neurol Neurosurg Psychiatry 2001;70:15-21.
6. Gaily E, Kantola-Sorsa E, Hiilesmaa V, et al. Normal intelligence in children with prenatal exposure to carbamazepine. Neurology 2004;62:28-32.