The serum of carcinoma patients powerfully activates carbonic anhydrase II

Experimental Oncology

Volumn 22, Issue 3, 2000, Pages 162-164

  Puscas, I ^a   Puscas, C ^a   Coltau, M ^a   Baican, M ^b   Domuta, G ^a  

^a ACADEMY OF ROMANIAN SCIENTISTS   (Romania)

^b Klinik Wilkenberg   (Germany)

Author keywords

Cancer patients; Carbonic anhydrase; Serum

Indexed keywords

EID: 0347056639     PISSN: 02043564     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Puscas I, Vlaicu R, Lazar A. Isosorbide nitrates, nitroglycerine and sodium nitroprusside induce vasodilation, concomitantly inhibiting down to abolishment carbonic anhydrase I in erythrocytes. Am J Hypertension, 1997; 10: 124-8.
2. Puscas I, Supuran CT. Carbonic anhydrase is an important physiological modulator. The pH Theory. In: I Puscas, ed. Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism. Helicon Publ House, Timisoara, Romania, 1994: 147-96.
3. Puscas I, Supuran CT. Carbonic anhydrase, a modulator of the physiological and pathological processes in the organism: The theory of pH. In: The 4th Int Conference on the Carbonic Anhydrases. Molecular Biology, Physiology and Clinical Applications, Oxford, 1995: 76.
4. Puscas I, Coltau M, Supuran CT. Non-steroidal antiinflammatory drugs inhibit cyclooxygenase and activate carbonic anhydrase. In: I Puscas, ed. Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism. Helicon Publ. House, Timisoara, Romania, 1994: 339-40.
5. Puscas I, Coltau M, Pasca R. Nonsteroidal antiinflammatory drugs activate carbonic anhydrase by a direct mechanism of action. J Pharmacol Exp Ther, 1996; 277: 1146-8.
6. Puscas I, Coltau M, Supuran CT. Non-steroidal anti-inflammatory drugs activate carbonic anhydrase by a direct mechanism of action. In: I Puscas ed. Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism, Helicon Publ House, Timisoara, Romania, 1994: 341-7.
7. 4 increase carbonic anhydrase activity. Int J Clin Pharmacol Therapeutics, 1995; 32: 176-81.
8. Puscas I, Puscas C. Prostaglandin-induced vasoconstriction and vasodilation are mediated by carbonic anhydrase. In: I Puscas, ed. Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism. Helicon Publ House, Timisoara, Romania, 1994: 322-7.
9. Puscas C, Vlaicu R, Coltau M, Maghiar A, Domuta G, Puscas I. Anticancer chemotherapy increases red cell and gastric mucosa carbonic anhydrase. Digestive Disease Week, San Francisco, 1996: A579.
10. Puscas C, Puscas I. Carcinogenic substances decrease gastric mucosa and red cell CA II activity. In: The Forum of Gastroenterology "Banat-Crisana" Timisoara, Romania, 1996: 11.
11. Puscas I, Coltau M, MaghairA, Cladovan C. Inhibition and activation of Superoxide dismutase and of carbonic anhydrase in ex vivo with benzo(a)pyrene and cyclophosphamide in patients with gastric cancer as compared to controls. Romanian J Gastroenterology, 1995: 21.
12. Puscas I, Coltau M, Puscas C. The relationship between CA I, CA II, non-steroidal anti-inflammatory drugs and some carcinogenic substances. Digestive Disease Week, San Diego, 1995: A912.
13. Puscas I, Maghiar A, Coltau M, Baican M, Domuta G. The carbonic anhydrase activation is involved in the chemopreventive, antitumor effects of non-steroidal anti-inflammatory drugs. Exp Oncol, 1999; 21: 121-6.
14. Puscas I, Coltau M, Rasnita T. Tumoral markers, such as sialic acid and a1-antichymothrypsine, are powerful activators of carbonic anhydrase II. Muticentric study. In: The XI* World Congresses of Gastroenterology, Vienna, 1998:2172.
15. Her2 activates the isozyme II of carbonic anhydrase. Digestive Disease Week, New Orleans, 1998: 2790.
16. Khalifah RG. The carbon dioxide hydration activity of carbonic anhydrase: stop-flow kinetic studies on the native human isozymes B and C. J Biol Chem, 1971; 246: 2561-73.
17. th World Congresses of Gastroenterology, Vienna, 1998: 2165.
18. th World Congresses of Gastroenterology, Vienna, 1998: 5213.
19. th World Congresses of Gastroenterology, Vienna, 1998: 2171.
20. Puscas I. Histamine is a direct activator of carbonic anhydrase. In: I Puscas, ed. Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism. Helicon Publ House, Timisoara, Romania, 1994: 388-400.
21. Coltau M, Puscas C, Pasca R, Kun C. Pentagastrin activates carbonic anhydrase by a direct mechanism (in vivo and in vitro studies). In: I Puscas, ed. Carbonic Anhydrase and Modulation of Physiologic and Pathologic Processes in the Organism. Helicon Publ House, Timisoara, Romania, 1994: 409-413.
22. Puscas I, Puscas C, Coltau M, Domuta G. The serum of gastric carcinoma patients explosively activates purified carbonic anhydrase II activity as compared to controls. Method of rapid diagnose of gastric cancer. Digestive Disease Week, Washington DC, 1997: 682.
23. Puscas I, Coltau M, Ghilezan N, Rasnita T, Tazar L, Pacurar V, Maghiar A, Micle O, Maghiar T, Pop I. The serum of digestive, hepatic and pancreatic cancer patients powerfully activates carbonic anhydrase II. Rapid diagnose method. Multicentric study. Digestive Disease Week, New Orleans, 1998: 1445.