Preparation of Antibody against Antitumor β-Glucan in Grifola frondosa and Its Application

Food Science and Technology Research

Volumn 5, Issue 4, 1999, Pages 398-401

  Mizuno, Masashi ^a   Yamakawa, Akio ^a   Minato, Ken Ichiro ^a   Kawakami, Sachiko ^a   Tatsuoka, Shigenobu ^a   Terai, Hirofumi ^a   Tsuchida, Hironobu ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

Anti tumor polysaccharides; ELISA; Grifola frondosa; Immunomodulating effect; Polyclonal antibody

Indexed keywords

BASIDIOMYCOTA; GRIFOLA FRONDOSA; ORYCTOLAGUS CUNICULUS;

EID: 0347031863     PISSN: 13446606     EISSN: None     Source Type: Journal    
DOI: 10.3136/fstr.5.398     Document Type: Article

References (22)

1. Adachi, Y., Ohno, N., Ohsawa, M., Sato, K., Oikawa, S. and Yadomae, T. (1989). Physiochemical properties and antitumor activities of chemically modified derivatives of antitumor glucan "grifolan LE" from Grifola frondosa. Chem. Pharm. Bull., 37, 1838-1843.
2. Adachi, Y., Ohno, N. and Yadomae, T. (1994). Preparation and antigen specificity of an anti-(1-→3)-β-D-glucan antibody. Biol. Pharm. Bull., 17, 1508-1512.
3. Chihara, G., Maeda, Y., Hamuro, J., Sasaki, T. and Fukuoka, F. (1969). Inhibition of mouse sarcoma 180 by polysaccharides from Lentinus edodes (Berk.) Sing. Nature, 222, 687-688.
4. Chihara, G., Hamuro, J., Maeda, Y., Arai, Y. and Fukuoka, F. (1970). Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom). Cancer Res., 30, 2776-2781.
5. Hashimoto, T., Ohno, N., Adachi, Y. and Yadomae, T. (1997). Nitric oxide synthesis in murine peritoneal macrophages by fungal β-glucans. Biol. Pharm. Bull., 20, 1006-1009.
6. Hirata, A., Adachi, Y., Itoh, W., Komoda, M., Tabata, K. and Sugawara, I. (1994). Monoclonal antibody to proteoglycan derived from Grifola frondosa (Maitake). Biol. Pharm. Bull., 17, 539-542.
7. Kerékgyártó, C., Virág, L., Tankó, L., Chihara, G. and Fachet, J. (1996). Strain differences in the cytotoxic activity and TNF production of murine macrophages stimulated by lentinan. Int. J. Immunopharmacol., 18, 347-353.
8. Lorsbach, R.B., Murphy, W.J., Lowenstein, C.J., Snyder, S.H. and Russell, S.W. (1993). Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. J. Biol. Chem., 268, 1908-1913.
9. Lowenstein, C.J. and Snyder, S.H. (1992). Nitric oxide, a novel biologic messenger. Cell, 70, 705-707.
10. Minamide, T., Habu, T. and Ogata, K. (1980). Effect of storage temperature on keeping freshness of mushroom after harvest. J. Jpn. Soc. Food Sci. Technol. 27, 281-287
11. Minato, K., Mizuno, M., Terai, H. and Tuchida, H. (1999). Autolysis of lentinan, an antitumor polysaccharide, during storage of Lentinus edodes, shiitake mushroom. J. Agric. Food Chem., 47, 1530-1532.
12. Mizuno, M., Minato, K. and Tuchida, H. (1996). Preparation and specificity of antibodies to an anti-tumor β-glucan, lentinan. Biochem. Mol. Bio. Int., 39, 679-685.
13. Nanba, H., Hamaguchi, A. and Kuroda, H. (1987). The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (Maitake). Chem. Pharm. Bull., 35, 1162-1168.
14. Ohno, N., Adachi, Y., Suzuki, I., Sato, K., Oikawa, S. and Yadomae, T. (1986a). Characterization of the antitumor glucan obtained from liquid-cultured Grifola frondosa. Chem. Pharm. Bull., 34, 1709-1715.
15. Ohno, N., Hayashi, M., Iino, K., Suzuki, I., Oikawa, S., Sato, K., Suzuki, Y. and Yadomae, T. (1986b). Effect of glucans on the antitumor activity of grifolan. Chem. Pharm. Bull., 34, 2149-2154.
16. Ohno, N., Egawa, Y., Hashimoto, T., Adachi, Y. and Yadomae, T. (1996). Effect of β-glucans on the nitric oxide synthesis by peritoneal macrophage in mice. Biol. Pharm. Bull., 19, 608-612.
17. Sasaki, T. and Takasuka, N. (1976). Further study of the structure of lentinan, an anti-tumor polysaccharide from Lentinus edodes. Carbohydr. Res., 47, 99-104.
18. Stuehr, D.J. and Nathan, C.F. (1989). Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. J. Exp. Med., 169, 1543-1555.
19. Takano, Y., Yagita, H., Iida, N., Hashimoto, H., Okumura, K. and Hirose, S. (1988). Relation between the level of IgG subclasses and infections in patients with systemic lupus erythematosus. Int. Arch. Allergy Appl. Immunol., 87, 55-58.
20. Takeyama, T., Suzuki, I., Ohno, N., Oikawa, S., Sato, K., Ohsawa, M. and Yadomae, T. (1987). Host-mediated antitumor effect of grifolan NMF-5N, a polysaccharide obtained from Grifola frondosa. J. Pharmacobio-Dyn., 10, 644-651.
21. Yoshida, H., Fujimoto, S. and Hayashi, J. (1991). Changes in the contents of carbohydrates and organic acids in fruit-bodies of mai take-mushroom [Grifola frondosa (Fr.) S. F. Gray] during storage. J. Jpn. Soc. Cold Preserv. Food, 17, 45-52.
22. Xie, O.-W., Cho, H.J., Calaycay, J., Mumford, R.A., Swiderek, K.M., Lee, T.D., Ding, A., Troso, T. and Nathan, C. (1992). Cloning and characterization of inducible nitric oxide synthase from mouse macrophages. Science, 256, 225-228.