Bilateral testicular microlithiasis predicts the presence of the precursor of testicular germ cell tumors in subfertile men

Journal of Urology

Volumn 171, Issue 1, 2004, Pages 158-160

  De Gouveia Brazao, C A ^a   Pierik, F H ^a   Oosterhuis, J W ^a   Dohle, G R ^a   Looijenga, L H J ^a   Weber, R F A ^a  

^a JOSEPHINE NEFKENS INSTITUTE   (Netherlands)

Author keywords

Carcinoma in situ; Germinoma; Lithiasis; Testis; Ultrasonography

Indexed keywords

ADULT; ARTICLE; CANCER RISK; CARCINOMA IN SITU; GERM CELL TUMOR; HISTOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; NON SEMINOMATOUS GERMINOMA; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCROTUM; SEMINOMA; SUBFERTILITY; TESTICULAR MICROLITHIASIS; TESTIS BIOPSY; TESTIS DISEASE; ULTRASOUND;

EID: 0346995351     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000093440.47816.88     Document Type: Article

References (20)

1. Parra, B. L., Venable, D. D., Gonzalez, E. and Eastham, J. A.: Testicular microlithiasis as a predictor of intratubular germ cell neoplasia. Urology, 48: 797, 1996
2. Peterson, A. C., Bauman, J. M., Light, D. E., McMann, L. P. and Costabile, R. A.: The prevalence of testicular microlithiasis in an asymptomatic population of men 18 to 35 years old. J Urol, 166: 2061, 2001
3. von Eckardstein, S., Tsakmakidis, G., Kamischke, A., Rolf, C. and Nieschlag, E.: Sonographic testicular microlithiasis as an indicator of premalignant conditions in normal and infertile men. J Androl, 22: 818, 2001
4. Jacobsen, R., Bostofte, E., Engholm, G., Hansen, J., Olsen, J. H., Skakkebaek, N. E. et al: Risk of testicular cancer in men with abnormal semen characteristics: cohort study. BMJ, 321: 789, 2000
5. Nicolas, F., Dubois, R., Laboure, S., Dodat, H., Canterino, I. and Rouviere, O.: Testicular microlithiasis and cryptorchism: ultrasound analysis after orchidopexy. Prog Urol, 11: 357, 2001
6. Schrey, A., Reiter, W. J. and Kratzik, C.: Value of ultrasound in microlithiasis of the testis in andrological patients. Ultraschall Med, 22: 143, 2001
7. Thomas, K., Wood, S. J., Thompson, A. J., Pilling, D. and Lewis-Jones, D. I.: The incidence and significance of testicular microlithiasis in a subfertile population. Br J Radiol, 73: 494, 2000
8. Pierik, F. H., Dohle, G. R., van Muiswinkel, J. M., Vreeburg, J. T. M. and Weber, R. F. A.: Is routine scrotal ultrasound advantageous in infertile men? J Urol, 162: 1618, 1999
9. Derogee, M., Bevers, R. F., Prins, H. J., Jonges, T. G., Elbers, F. H. and Boon, T. A.: Testicular microlithiasis, a premalignant condition: prevalence, histopathologic findings, and relation to testicular tumor. Urology, 57: 1133, 2001
10. Ganem, J. P., Workman, K. R. and Shaban, S. F.: Testicular microlithiasis is associated with testicular pathology. Urology, 53: 209, 1999
11. Riebel, T., Herrmann, C., Wit, J. and Sellin, S.: Ultrasonographic late results after surgically treated cryptorchidism. Pediatr Radiol, 30: 151, 2000
12. Miller, F. N. and Sidhu, P. S.: Does testicular microlithiasis matter? A review. Clin Radiol, 57: 883, 2002
13. Patel, M. D., Olcott, E. W., Kerschmann, R. L., Callen, P. W. and Gooding, G. A.: Sonographically detected testicular microlithiasis and testicular carcinoma. J Clin Ultrasound, 21: 447, 1993
14. Giwercman, A., Müller, J. and Skakkebæk, N. E.: Prevalence of carcinoma in situ and other histopathological abnormalities in testes from 399 men who died suddenly and unexpectedly. J Urol, 145: 77, 1991
15. Backus, M. L., Mack, L. A., Middleton, W. D., King, B. F., Winter, T. C., 3rd and True, L. D.: Testicular microlithiasis: imaging appearances and pathologic correlation. Radiology, 192: 781, 1994
16. Giwercman, A., Muller, J. and Skakkebæk, N. E.: Carcinoma in situ of the undescended testis. Semin Urol, 6: 110, 1988
17. Bach, A. M., Hann, L. E., Shi, W., Giess, C. S., Yoo, H. H., Sheinfeld, J. et al: Is there an increased incidence of contralateral testicular cancer in patients with intratesticular microlithiasis? AJR Am J Roentgenol, 180: 497, 2003
18. Leenen, A. S. and Riebel, T. W.: Testicular microlithiasis in children: sonographic features and clinical implications. Pediatr Radiol, 32: 575, 2002
19. Drut, R. and Drut, R. M.: Testicular microlithiasis: histologic and immunohistochemical findings in 11 paediatric cases. Pediatr Dev Pathol, 5: 544, 2002
20. Dieckmann, K.-P., Souchon, R., Hahn, E. and Loy, V.: False-negative biopsies for testicular intraepithelial neoplasia. J Urol, 162: 364, 1999