Assessment of equine autoimmune thrombocytopenia (EAT) by flow cytometry

BMC Blood Disorders

Volumn 1, Issue , 2001, Pages

  Nunez, Rafael ^a,b   Gomes Keller, M Alice ^a   Schwarzwald, Colin ^a   Feige, Karsten ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; DEXAMETHASONE; IMMUNOGLOBULIN G; PREDNISOLONE;

ARTICLE; AUTOIMMUNE DISEASE; BLOOD ANALYSIS; CELL DESTRUCTION; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DISEASE CLASSIFICATION; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; HORSE; NON INVASIVE MEASUREMENT; NONHUMAN; PATHOGENESIS; RELIABILITY; THROMBOCYTE; THROMBOCYTE COUNT; THROMBOCYTE STRUCTURE; THROMBOCYTE VOLUME; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS;

EID: 0346910287     PISSN: 14712326     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2326-1-1     Document Type: Article

References (18)

1. Sellon DC, Levine J, Millikin E, Palmer K, Grindem C, Covington P: Thrombocytopenia in horses: 35 cases (1989-1994). J Vet Intern Med 1996, 10:127-31
2. Newman PJ, Derbes RS, Aster RH: The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. J Clin Invest 1989, 83:1778-81
3. Byars TD, Greene CE: Idiopathic thrombocytopenic purpura in the horse. J Am Vet Med Assoc 1982, 180:1422-4
4. Larson VL, Perman V, Stevens JB: Idiopathic thrombocytopenic purpura in two horses. J Am Vet Med Assoc 1983, 183:328-30
5. Clabough DL, Gebhard D, Flaherty MT, Whetter LE, Perry ST, Coggins L, Fuller FJ: Immune-mediated thrombocytopenia in horses infected with equine infectious anemia virus. J Virol 1991, 65:6242-51
6. Reef VB, Dyson SS, Beech J: Lymphosarcoma and associated immune-mediated hemolytic anemia and thrombocytopenia in horses. J Am Vet Med Assoc 1984, 84:313-7
7. Cohen ND, Carter GK: Persistent thrombocytopenia in a case of equine infectious anemia. J Am Vet Med Assoc 1991, 199:750-2
8. Sellon DC, Walker KM, Russell KE, Perry ST, Covington P, Fuller FJ: Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses. J Virol 1996, 70:590-4
9. Wardrop KJ, Baszler TV, Reilich E, Crawford TB: A morphometric study of bone marrow megakaryocytes in foals infected with equine infectious anemia virus. Vet Pathol 1996, 33:222-7
10. George JN: Platelet immunoglobulin G: its significance for the evaluation of thrombocytopenia and for understanding the origin of alpha-granule proteins. Blood 1990, 76:859-70
11. George JN, Saucerman S, Levine SP, Knieriem LK, Bainton DF: Immunoglobulin G is a platelet alpha granule-secreted protein. J Clin Invest 1985, 76:2020-5
12. George JN, Raskob GE: Idiopathic thrombocytopenic purpura: A concise summary of the pathophysiology and diagnosis in children and adults. Semin Hematol 1998, 35:5-8
13. George JN: measurement, interpretation, and clinical significance. Prog Hemost Thromb 1991, 10:97-126
14. Handagama PJ, Shuman MA, Bainton DF: The origin of platelet alpha-granule proteins. Prog Clin Biol Res 1990, 356:119-30
15. Holme S, Heaton A, Kunchuba A, Hartman P: Increased levels of platelet associated IgG in patients with thrombocytopenia are not confined to any particular size class of platelets. Br J Haematol 1988, 68:431-6
16. Holme S, Heaton A, Konchuba A, Hartman P: Light scatter and total protein signal distribution of platelets by flow cytometry as parameters of size. J Lab Clin Med 1988, 112:223-31
17. Hughes M, Hayward CP, Warkentin TE, Horsewood P, Chorneyko KA, Kelton JG: Morphological analysis of microparticle generation in heparin-induced thrombocytopenia. Blood 2000, 96:188-94
18. Hughes M, Webert K, Kelton JG: The use of electron microscopy in the investigation of the ultrastructural morphology of immune thrombocytopenic purpura platelets [In Process Citation]. Semin Hematol 2000, 37:222-8