Development of a l-μl scale assay for mitogen-activated kinase kinase 7 using 2-D fluorescence intensity distribution analysis anisotropy

Journal of Biomolecular Screening

Volumn 7, Issue 5, 2002, Pages 419-428

  Wright, Penny A ^a   Boyd, Helen F ^a   Bethell, Richard C ^a   Busch, Michael ^b   Gribbon, Phillip ^a   Kraemer, Joachim ^b   Lopez Calle, Eloisa ^b   Mander, Thomas H ^b   Winkler, Dirk ^b   Benson, Neil ^a,c  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^b EVOTEC UK LTD   (United Kingdom)

^c Sandwich Hit Discovery Group IPC 654   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 CARBOXYTETRAMETHYLRHODAMINE SUCCINIMIDYL ESTER; 5-CARBOXYTETRAMETHYLRHODAMINE SUCCINIMIDYL ESTER; ADENOSINE TRIPHOSPHATE; ENZYME INHIBITOR; LIGAND; MAGNESIUM; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 10; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; PEPTIDE FRAGMENT; PROTEIN TYROSINE KINASE; RHODAMINE; STRESS ACTIVATED PROTEIN KINASE 1;

ANTIBODY SPECIFICITY; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; FLUORESCENCE POLARIZATION; IC 50; IMMUNOLOGY; KINETICS; METABOLISM; METHODOLOGY; PHOSPHORYLATION; PROTEIN MOTIF; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ANTIBODY SPECIFICITY; ENZYME INHIBITORS; FLUORESCENCE POLARIZATION; INHIBITORY CONCENTRATION 50; KINETICS; LIGANDS; LINEAR MODELS; MAGNESIUM; MAP KINASE KINASE 7; MICROCHEMISTRY; MITOGEN-ACTIVATED PROTEIN KINASE 10; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; REPRODUCIBILITY OF RESULTS; RHODAMINES; SENSITIVITY AND SPECIFICITY;

EID: 0346910078     PISSN: 10870571     EISSN: None     Source Type: Journal    
DOI: 10.1177/108705702237673     Document Type: Article

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