Pregnancy outcome of 30 fetuses with cystic hygroma diagnosed during the first 15 weeks of gestation

Genetic Counseling

Volumn 14, Issue 4, 2003, Pages 413-418

  Paoloni Giacobino, A ^a   Extermann, D ^b   Extermann, Ph ^b   Dahoun, S P ^a,c  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^b Dianecho Center of Fetal Echograpphy   (Switzerland)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Cystic hygroma; Karyotype; Ultrasonography

Indexed keywords

AMNIOCENTESIS; ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; COLOBOMA; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; CYSTIC LYMPHANGIOMA; FEMALE; FETUS; FETUS ECHOGRAPHY; FETUS MALFORMATION; GENETIC COUNSELING; GESTATIONAL AGE; HUMAN; INTRAUTERINE GROWTH RETARDATION; KARYOTYPE; KLINEFELTER SYNDROME; MALE; MATERNAL AGE; MENINGOMYELOCELE; PALLISTER KILLIAN SYNDROME; PREGNANCY COMPLICATION; PREGNANCY TERMINATION; PRENATAL DIAGNOSIS; PROGNOSIS; TRISOMY 13; TRISOMY 18; TRISOMY 21; TURNER SYNDROME;

ABNORMALITIES; ADULT; CHROMOSOME ABERRATIONS; FEMALE; GENETIC COUNSELING; HUMANS; KARYOTYPING; LYMPHANGIOMA, CYSTIC; PREGNANCY; PREGNANCY OUTCOME; SWITZERLAND; ULTRASONOGRAPHY, PRENATAL;

EID: 0346895083     PISSN: 10158146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. ABRAMOWICZ J.S., WARSOF S.L., DOYLE D.L., SMITH D., LEVY D.L.: Congenital cystic hygroma of the neck diagnosed prenatally: outcome with normal and abnormal karyotype. Prenat. Diagn., 1989, 9, 321-327.
2. ADEKUNLE O., GOPEE A., EL-SAYED M., THILAGANATHAN B.: Increased first trimester nuchal translucency: pregnancy and infant outcomes after routine screening for Down's syndrome in an unselected antenatal population. Br. J. Radiol., 1999, 72, 457-460.
3. AZAR G.B., SNIJDERS R.J., GOSDEN C., NICOLAIDES K.H.: Fetal nuchal cystic hygromata: associated malformations and chromosomal defects. Fetal Diagn. Ther., 1991, 6, 46-57.
4. BERNSTEIN H.S., FILLY R.A., GOLDBERG J.D., GOLBUS M.S.: Prognosis of fetuses with a cystic hygroma. Prenat. Diagn., 1991, 11, 349-355.
5. BEWLEY S., ROBERTS L.J., MACKINSON A.M., RODECK C.H.: First trimester fetal nuchal translucency: problems with screening the general population. 2. Br. J. Obstet. Gynaecol., 1995, 102, 386-388.
6. CARVALHO M.H., BRIZOT M.L., LOPES L.M., CHIBA C.H., MIYADAHIRA S., ZUGAIB M.: Detection of fetal structural abnormalities at the 11-14 week ultrasound scan. Prenal. Diagn., 2002, 22, 1-4.
7. CHITTY L.N., PANDYA P.P.: Ultrasound screening for fetal abnormailies in the first trimester. Prenat. Diagn., 1997, 17, 1269-1281.
8. DE VIGAN C., BAENA N., CARIATI E., CLEMENTI M., STOLL C.: Contribution of ultrasonographic examination to the prenatal detection of chromosomal abnormalities in 19 centres across Europe. Ann. Genet., 2001, 44, 209-217.
9. HIIPPALA A., ERONEN M., TAIPALE P., SALONEN R., HIILESMAA V.: Fetal nuchal translucency and normal chromosomes: a long-term follow-up study. Ultrasound Obstet. Gynecol., 2001, 18, 18-22.
10. HYETT J., THILAGANATHAN B.: First trimester screening for fetal abnormalities. Curr. Opin. Obstet. Gynecol., 1999, 11, 563-569.
11. JOHNSON M.P., JOHNSON A., HOLZGREVE W., ISADA N.B., WAPNER R.J., TREADWELL M.C., HEEGER S., EVANS M.I.: First-trimester simple hygroma: cause and outcome. Am. J. Obstet. Gynecol., 1993, 168, 156-161.
12. LANGFORD K., HODGSON S., SELLER M., MAXWELL D.: Pallister-Killian syndrome presenting through nuchal translucency screening for trisomy 21. Prenat. Diagn., 2000, 20, 670-672.
13. MICHAILIDIS G.D., ECONOMIDES D.L.: Nuchal translucency measurement and pregnancy outcome in karyotypically normal fetuses. Ultrasound Obstet. Gynecol., 2001, 17, 102-105.
14. PODOBNIK M., SINGER Z., PODOBNIK-SARKANJI S., BULIC M.: First trimester diagnosis of cystic hygromata using transvaginal ultrasound and cytogenetic evaluation. J Perinat. Med., 1995, 23, 283-291.
15. ROSATI P., GUARIGLIA L.: Prognostic value of ultrasound findings of fetal cystic hygroma detected in early pregnancy by transvaginal sonography. Ultrasound Obstet. Gynecol., 2000, 16, 245-250.
16. SHULMAN L.P., EMERSON D.S., FELKER R.E., PHILLIPS O.P., SIMPSON J.L., ELIAS S.: High frequency of cytogenetic abnormalities in fetuses with cystic hygroma diagnosed in the first trimester. Obstet. Gynecol., 1992, 80, 80-82.
17. SNIJDERS R.J., NOBLE P., SEBIRE N., SOUKA A., NICOLAIDES K.H.: UK multicentre project on assessment of risk of trisomy 21 by maternal age and fetal nuchal-translucency thickness at 10-14 weeks of gestation. Fetal Medicine Foundation First Trimester Screening Group. Lancet, 1998, 352, 343-346.
18. SOUKA A.P., SNIJDERS R.J., NOVAKOV A., SOARES W., NICOLAIDES K.H.: Defects and syndromes in chromosomally normal fetuses with increased nuchal translucency thickness at 10-14 weeks of gestation. Ultrasound Obstet. Gynecol., 1998, 11, 391-400.
19. SOUKA A.P., KRAMPL E., BAKALIS S., HEATH V. NICOLAIDES K.H.: Outcome of pregnancy in chromosomally normal fetuses with increased nuchal translucency in the first trimester. Ultrasound Obstet. Gynecol., 2001, 18, 9-17.
20. SZABO J., GELLEN J., SZEMERE G.: First-trimester ultrasound screening for fetal aneuploidies in women over 35 and under 35 years of age. Ultrasound Obstet. Gynecol., 1995, 5, 161-163.
21. VAN VUGT J.M., TINNEMANS B.W., VAN ZALENSPROCK R.M.: Outcome and early childhood follow-up of chromosomally normal fetuses with increased nuchal translucency at 10-14 weeks gestation. Ultrasound Obstet. Gynecol., 1998, 11, 407-409.