Silyl modification of biologically active compounds. 9. Synthesis and biological activity of novel 1,3-disilabenzo[5,6]cyclohexene derivatives

Chemistry of Heterocyclic Compounds

Volumn 39, Issue 6, 2003, Pages 813-818

  Lukevics, E ^a   Zablotskaya, A ^a   Segal, I ^a   Germane, S ^a   Popelis, J ^a  

^a LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

Author keywords

1,3 disilabenzo 5,6 cyclohexene; 29Si NMR; Chlorosilane; Cyclization; Organosilicon compounds; Psychotropic activity; Spirocycle; Transannular interaction

Indexed keywords

(2 BROMOMETHYLPHENYL)DIMETHYLCHLOROSILANE; 1,3 DISILABENZO[5,6]CYCLOHEXENE DERIVATIVE; 3 (3 CHLOROPROPYL) 1,1,3 TRIMETHYL 1,3 DISILABENZO[5,6]CYCLOHEXENE; 3',3',5 TRIMETHYL 2,8 DIOXA 5 AZA 1 SILACYCLOOCTANE 1 SPIRO 1' (1',3' DISILABENZO[4,5]CYCLOHEXENE); 3',3',5' TRIMETHYL 2,8 DIOXA 5 AZA 1 SILACYCLOOCTANE 1 SPIRO 1' (1',3' DISILABENZO[4',5']CYCLOHEXENE); 3,3 DIETHOXY 1,1 DIMETHYL 1,3 DISILABENZO[5,6]CYCLOHEXENE; NITROGEN; ORGANOSILICON DERIVATIVE; ORTHO XYLENE; PSYCHOTROPIC AGENT; SEDATIVE AGENT; SILANE DERIVATIVE; SILICON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLIZATION; DRUG ACTIVITY; DRUG SYNTHESIS; LD 50; MALE; MEMORY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT; STRESS;

EID: 0346874209     PISSN: 00093122     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025667717347     Document Type: Article

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