Potent Small-Molecule Binding to a Dynamic Hot Spot on IL-2

Journal of the American Chemical Society

Volumn 125, Issue 50, 2003, Pages 15280-15281

  Thanos, Christopher D ^a,b   Randal, Mike ^a   Wells, James A ^a  

^a Sunesis Pharmaceuticals Inc   (United States)

^b Catalyst Biosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2;

ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL STRUCTURE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; MOLECULAR DYNAMICS; MOLECULAR SIZE; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; SURFACE PROPERTY; TECHNIQUE;

BINDING SITES; DRUG DESIGN; INTERLEUKIN-2; PROTEIN CONFORMATION;

EID: 0346850033     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0382617     Document Type: Article

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