Tumor marker levels in post-chemotherapy cystic masses: Clinical implications for patients with germ cell tumors

Journal of Urology

Volumn 171, Issue 1, 2004, Pages 168-171

  Beck, Stephen D W ^a   Patel, Manish I ^a,b   Sheinfeld, Joel ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Cysts; Teratoma; Testicular neoplasms; Tumor markers, biological

Indexed keywords

ALPHA FETOPROTEIN; BLEOMYCIN; CHORIONIC GONADOTROPIN; CISPLATIN; ETOPOSIDE; TUMOR MARKER;

ARTICLE; CANCER CHEMOTHERAPY; CLINICAL ARTICLE; CYST; GERM CELL TUMOR; HUMAN; LYMPH NODE DISSECTION; MALE; MALIGNANT TRANSFORMATION; ORCHIECTOMY; PARAAORTIC LYMPH NODE; PRIORITY JOURNAL; RETROPERITONEUM; TESTIS TERATOMA; YOLK SAC TUMOR;

EID: 0346848831     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000099714.16082.78     Document Type: Article

References (15)

1. Lange, P. H., Vogelzang, N. J., Goldman, A., Kennedy, B. J. and Fraley, E. E.: Marker half-life analysis as a prognostic tool in testicular cancer. J Urol, 128: 708, 1982
2. Albers, P., Ganz, A., Hannig, E., Miersch, W.-D. E. and Müller, S. C.: Salvage surgery of chemorefractory germ cell tumors with elevated tumor markers. J Urol, 164: 381, 2000
3. Beck, S. D., Foster, R. S., Bihrle, R., Koch, M. O., Wahle, G. R., Einhorn, L. et al: Post chemotherapy desperation retroperitoneal lymph node dissection for patients with elevated tumor markers. J Urol, suppl., 165: 154, abstract, 632, 2001
4. Coogan, C. L., Foster, R. S., Rowland, R. G., Bihrle, R., Smith, E. R., Jr., Einhorn, L. H. et al: Postchemotherapy retroperitoneal lymph node dissection is effective therapy in selected patients with elevated tumor markers after primary chemotherapy alone. Urology, 50: 957, 1997
5. Eastham, J. A., Wilson, T. G., Russell, C., Ahlering, T. E. and Skinner, D. G.: Surgical resection in patients with nonseminomatous germ cell tumor who fail to normalize serum tumor markers after chemotherapy. Urology, 43: 74, 1994
6. Murphy, B. R., Breeden, E. S., Donohue, J. P., Messemer, J., Walsh, W., Roth, B. J. et al: Surgical salvage of chemorefractory germ cell tumors. J Clin Oncol, 11: 324, 1993
7. Ravi, R., Ong, J., Oliver, R. T., Badenoch, D. F., Fowler, C. G. and Hendry, W. F.: Surgery as salvage therapy in chemotherapy-resistant nonseminomatous germ cell tumours. Br J Urol, 81: 884, 1998
8. Wood, D. P., Jr., Herr, H. W., Motzer, R. J., Reuter, V., Sogani, P. C., Morse, M. J. et al: Surgical resection of solitary metastases after chemotherapy in patients with nonseminomatous germ cell tumors and elevated serum tumor markers. Cancer, 70: 2354, 1992
9. Catalona, W. J., Vaitukaitis, J. L. and Fair, W. R.: Falsely positive specific human chorionic gonadotropin assays in patients with testicular tumors: conversion to negative with testosterone administration. J Urol, 122: 126, 1979
10. Fowler, J. E., Jr., Platoff, G. E., Kubrock, C. A. and Stutzman, R. E.: Commercial radioimmunoassay for beta subunit of human chorionic gonadotropin: falsely positive determinations due to elevated serum luteinizing hormone. Cancer, 49: 136, 1982
11. Odell, W. D. and Griffin, J.: Pulsatile secretion of human chorionic gonadotropin in normal adults. N Engl J Med, 317: 1688, 1987
12. Doherty, A. P., Bower, M. and Christmas, T. J.: The role of tumour markers in the diagnosis and treatment of testicular germ cell cancers. Br J Urol, 79: 247, 1997
13. Van Der Gaast, A., Hoekstra, J. W., Croles, J. J. and Splinter, T. A. W.: Elevated serum tumor markers in patients with testicular cancer after induction chemotherapy due to a reservoir of markers in cystic differentiated mature teratoma. J Urol, 145: 829, 1991
14. Beck, S. D. W., Foster, R. S., Bihrle, R., Ulbright, T., Koch, M. O., Wahle, G. R. et al: Teratoma in the orchiectomy specimen and volume of metastasis are predictors of retroperitoneal teratoma in post-chemotherapy nonseminomatous testis cancer. J Urol, 168: 1402, 2002
15. International Germ Cell Consensus Classification: A prognostic factor-based staging system for metastatic germ cell cancers. International Germ Cell Cancer Collaborative Group. J Clin Oncol, 15: 594, 1997