Genomic organization and characterization of the promoter for the E2A gene

Gene

Volumn 325, Issue 1-2, 2004, Pages 53-61

  Hata, Kikumi ^a   Mizuguchi, Junichiro ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

B cells; E2A; Genome; Promoter

Indexed keywords

HELIX LOOP HELIX PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E2A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CIS ISOMER; CONTROLLED STUDY; DNA FLANKING REGION; DNA TRANSFECTION; EMBRYO; EXON; FIBROBLAST; GEL MOBILITY SHIFT ASSAY; GENE ACTIVITY; GENE CONTROL; GENE DELETION; GENE INTERACTION; GENE ISOLATION; GENOME ANALYSIS; LYMPHOCYTE; MOLECULAR CLONING; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; TATA BOX; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION;

EID: 0346789058     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2003.09.040     Document Type: Article

References (28)

1. Azizkhan J.C., Jensen D.E., Pierce A.J., Wade M. Transcription from TATA-less promoters: dihydrofolate reductase as a model. Crit. Rev. Eukaryot. Gene Expr. 3:1993;229-254.
2. Bain G., Maandag E.C., Izon D.J., Amsen D., Kruisbeek A.M., Weintraub B.C., Krop I., Schlissel M.S., Feeney A.J., van Roon M.et al. E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements. Cell. 79:1994;885-892.
3. Bain G., Engel I., Robanus Maandag E.C., te Riele H.P., Voland J.R., Sharp L.L., Chun J., Huey B., Pinkel D., Murre C. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol. Cell Biol. 17:1997;4782-4791.
4. Briggs M.R., Kadonaga J.T., Bell S.P., Tjian R. Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science. 234:1986;47-52.
5. DeFranco A.L., Gold M.R., Jakway J.P. B-lymphocyte signal transduction in response to anti-immunoglobulin and bacterial lipopolysaccharide. Immunol. Rev. 95:1987;161-176.
6. Engel I., Murre C. The function of E-and Id proteins in lymphocyte development. Nat. Rev., Immunol. 1:2001;193-199.
7. Fry C.J., Farnham P.J. Context-dependent transcriptional regulation. J. Biol. Chem. 274:1999;29583-29586.
8. Goldfarb A.N., Flores J.P., Lewandowska K. Involvement of the E2A basic helix-loop-helix protein in immunoglobulin heavy chain class switching. Mol. Immunol. 33:1996;947-956.
9. Hilger-Eversheim K., Moser M., Schorle H., Buettner R. Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control. Gene. 260:2000;1-12.
10. Huggins G.S., Chin M.T., Sibinga N.E., Lee S.L., Haber E., Lee M.E. Characterization of the mUBC9-binding sites required for E2A protein degradation. J. Biol. Chem. 274:1999;28690-28696.
11. Kee B.L., Quong M.W., Murre C. E2A proteins: essential regulators at multiple stages of B-cell development. Immunol. Rev. 175:2000;138-149.
12. Lowry J.A., Atchley W.R. Molecular evolution of the GATA family of transcription factors: conservation within the DNA-binding domain. J. Mol. Evol. 50:2000;103-115.
13. Massari M.E., Murre C. Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol. Cell Biol. 20:2000;429-440.
14. Mayr B., Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat. Rev., Mol. Cell Biol. 2:2001;599-609.
15. Murre C., McCaw P.S., Baltimore D. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell. 56:1989;777-783.
16. Norton J.D. ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis. J. Cell Sci. 113(Pt. 22):2000;3897-3905.
17. Ogbourne S., Antalis T.M. Transcriptional control and the role of silencers in transcriptional regulation in eukaryotes. Biochem. J. 331(Pt. 1):1998;1-14.
18. Perez-Moreno M.A., Locascio A., Rodrigo I., Dhondt G., Portillo F., Nieto M.A., Cano A. A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions. J. Biol. Chem. 276:2001;27424-27431.
19. Quong M.W., Harris D.P., Swain S.L., Murre C. E2A activity is induced during B-cell activation to promote immunoglobulin class switch recombination. EMBO J. 18:1999;6307-6318.
20. Reya T., Grosschedl R. Transcriptional regulation of B-cell differentiation. Curr. Opin. Immunol. 10:1998;158-165.
21. Roberts V.J., Steenbergen R., Murre C. Localization of E2A mRNA expression in developing and adult rat tissues. Proc. Natl. Acad. Sci. U. S. A. 90:1993;7583-7587.
22. Rutherford M.N., LeBrun D.P. Restricted expression of E2A protein in primary human tissues correlates with proliferation and differentiation. Am. J. Pathol. 153:1998;165-173.
23. Santee S.M., Owen-Schaub L.B. Human tumor necrosis factor receptor p75/ 80 (CD120b) gene structure and promoter characterization. J. Biol. Chem. 271:1996;21151-21159.
24. Shapiro M.B., Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15:1987;7155-7174.
25. Shen C.P., Kadesch T. B-cell-specific DNA binding by an E47 homodimer. Mol. Cell. Biol. 15:1995;4518-4524.
26. Smale S.T. Transcription initiation from TATA-less promoters within eukaryotic protein-coding genes. Biochim. Biophys. Acta. 1351:1997;73-88.
27. Yan W., Young A.Z., Soares V.C., Kelley R., Benezra R., Zhuang Y. High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice. Mol. Cell. Biol. 17:1997;7317-7327.
28. Zhuang Y., Soriano P., Weintraub H. The helix-loop-helix gene E2A is required for B cell formation. Cell. 79:1994;875-884.