2-Methoxyestradiol induces caspase-independent, mitochondria-centered apoptosis in DS-sarcoma cells

International Journal of Cancer

Volumn 108, Issue 4, 2004, Pages 493-501

  Lambert, Christine ^a   Apel, Katrin ^a   Biesalski, Hans Konrad ^a   Frank, Juergen ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

Author keywords

2 Methoxyestradiol; AIF; Apoptosis; Bax; Endonuclease G; Mitochondria; Reactive oxygen species

Indexed keywords

2 METHOXYESTRADIOL; ANTIOXIDANT; APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 8; CASPASE INHIBITOR; ENDONUCLEASE; FAS LIGAND; ISOPROTEIN; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOMA CELL; UPREGULATION;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; CASPASES; ENDODEOXYRIBONUCLEASES; ENZYME ACTIVATION; ENZYME INHIBITORS; ESTRADIOL; FLAVOPROTEINS; MEMBRANE POTENTIALS; MEMBRANE PROTEINS; MITOCHONDRIA; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES; SARCOMA, EXPERIMENTAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0346787534     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.11579     Document Type: Article

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