Nickel-Catalyzed Arylation of Acrolein Diethyl Acetal: A Substitute to the 1,4-Addition of Arylhalides to Acrolein

Organic Letters

Volumn 5, Issue 24, 2003, Pages 4701-4703

  Condon, S ^a   Dupre D ^a   Nedelec J Y ^a  

^a CNRS Université Paris Est Créteil Val de Marne   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAL DERIVATIVE; ACROLEIN DERIVATIVE; ACROLEIN DIETHYLACETAL; HALIDE; NICKEL COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; ARYLATION; CATALYSIS; CATALYST; HYDROLYSIS; TEMPERATURE;

EID: 0346780612     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol035877s     Document Type: Article

References (11)

1. Condon-Gueugnot, S.; Léonel, E.; Nédélec, J. Y.; Périchon, J. J. Org. Chem. 1995, 60, 7684-7686.
2. Condon, S.; Dupré, D.; Falgayrac, G.; Nédélec, J. Y. Eur. J. Org. Chem. 2002, 105-111.
3. Condon, S.; Dupré, D.; Lachaise, I.; Nédélec, J. Y. Synthesis 2002, 1752-1758.
4. Condon-Gueugnot, S.; Dupré, D.; Nédélec, J. Y.; Périchon, J. Synthesis 1997, 1457-1460.
5. (a) Quelet, R.; D'Angelo, J. Bull. Soc. Chim. Fr. 1967, 1503-1511.
6. (b) Normant, J. F.; Commerçon. A.; Bourgain, M.; Villieras, J. Tetrahedron Lett. 1975, 16, 3833-3836.
7. (c) Mioskowski, C.; Manna. S.; Falck, J. R. Tetrahedron Lett. 1984, 25, 519-522.
8. (d) Mangeney, P.; Alexakis, A.; Normant, J. F. Tetrahedron Lett. 1986, 27, 3143-3146.
9. The cleanliness of this last procedure makes further purification unnecessary.
10. (a) Melpolder, J. B.; Heck, F. J. Org. Chem 1976, 41, 265-372.
11. (b) Jeffery, T. Tetrahedron Lett. 1991, 32, 2121-2124.