Quality of drug information on the World Wide Web and strategies to improve pages with poor information quality. An intervention study on pages about sildenafil

British Journal of Clinical Pharmacology

Volumn 57, Issue 1, 2004, Pages 80-85

  Martin Facklam, Meret ^a   Kostrzewa, Michael ^a   Martin, Peter ^a   Haefeli, Walter E ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Drug Information Services standards; Internet; Sildenafil

Indexed keywords

4 AMINOPHENOL; AMYL NITRITE; ANTIFUNGAL AGENT; CYTOCHROME P450 3A4; ERYTHRITYL TETRANITRATE; ERYTHROMYCIN; GLYCERYL TRINITRATE; INDINAVIR; ISOSORBIDE DINITRATE; ISOSORBIDE MONONITRATE; ITRACONAZOLE; KETOCONAZOLE; MACROLIDE; MOLSIDOMINE; NICORANDIL; NITRIC OXIDE; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; ORGANIC NITRATE; PENTAERYTHRITYL TETRANITRATE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; SILDENAFIL;

ACCURACY; ARTICLE; DRUG INFORMATION; DRUG SAFETY; DRUG USE; ELECTRONICS; EVALUATION; FEEDBACK SYSTEM; FLUSHING; HEADACHE; HUMAN; INTERNET; MEDICAL INFORMATION SYSTEM; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NORMAL HUMAN; PRIORITY JOURNAL; PUBLICATION; QUALITY CONTROL; RANDOMIZATION; SCIENTIFIC LITERATURE; SCORING SYSTEM; TYPES OF STUDY; VISUAL IMPAIRMENT;

DRUG INFORMATION SERVICES; DRUG INTERACTIONS; HUMANS; INTERNET; OBSERVER VARIATION; PIPERAZINES; REGRESSION ANALYSIS;

EID: 0346688575     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2003.01954.x     Document Type: Article

References (31)

1. Spadaro R. The European Opinion Research Group (EORG). Eurobarometer 58.0. European Union, citizens and sources of information about health, March 2003. Available from: URL http://europaeu.International/comm/health/ ph_information/ documents/EB_58_en.pdf. Accessed May 24 2003.
2. Gordon MM, Capell HA, Madhok R. The use of the Internet as a resource for health information among patients attending a rheumatology clinic. Rheumatology 2002; 41: 1402-5.
3. Baker L, Wagner TH, Singer S, Bundorf MK. Use of the internet and E-mail: for health care information: Results from a national survey. JAMA 2003; 289: 2400-6.
4. Pew Internet and American Life Project. The online health care revolution: How the Web helps Americans take better care of themselves November 26 2000. Available from: URL http:// www.pewinternet.org/reports/pdfs/ PIP_Health_Report.pdf. Accessed May 24 2003.
5. Eysenbach G, Powell J, Kuss O, Sa ER. Empirical studies assessing the quality of health information for consumers on the world wide web: a systematic review. JAMA 2002; 287: 2691-700.
6. Crocco AG, Villasis-Keever M, Jadad AR. Two wrongs don't make a right: harm aggravated by inaccurate information on the internet. Pediatrics 2002; 109: 522-3.
7. Silberg WM, Lundberg GD, Musacchio RA. Assessing, controlling, and assuring the quality of medical information on the internet. JAMA 1997; 277: 1244-5.
8. Charnock D, Shepperd S, Needham G, Gann R. DISCERN. an instrument for judging the quality of written consumer health information on treatment choices. J Epidemiol Community Health 1999; 53: 105-11.
9. Rees CE, Ford JE, Sheard CE. Evaluating the reliability of DISCERN. a tool for assessing the quality of written patient information on treatment choices. Patient Educ Couns 2002; 47: 273-5.
10. Gagliardi A, Jadad AR. Examination of instruments used to rate quality of health information on the internet: chronicle of a voyage with an unclear destination. Br Med J 2002; 324: 569-73.
11. Martin-Facklam M, Kostrzewa M, Schubert F, Gasse C, Haefeli WE. Quality markers of drug information on the internet. An evaluation of sites on St. John's Wort. Am J Med 2002; 113: 740-5.
12. HON Code of Conduct (HONcode) for medical and health web sites. Available from: URL http://www.hon.ch/HONcode/. Accessed May 24 2003.
13. Rippen H, Risk A. E-health code of ethics (May 24). J Med Internet Res 2000; 2: e9. Available from: URL http://www.jmir.org/2000/ 2/e9/index.htm. Accessed May 24 2003.
14. Wilson P. How to find the good and avoid the bad or ugly: a short guide to tools for rating quality of health information on the internet. Br Med J 2002; 324: 598-602.
15. Pfizer. US prescribing information of Viagra® (sildenafil citrate) tablets. Revised January 2000.
16. Bessell TL, Silagy CA, Anderson JN, Hiller JE, Sansom LN. Quality of global e-pharmacies: can we safeguard consumers? Eur J Clin Pharmacol 2002; 58: 567-72.
17. Armstrong EP, Chrischilles EA. Electronic prescribing and monitoring are needed to improve drug use. Arch Intern Med 2000; 160: 2713-14.
18. Bloom BS, Iannacone RC. Internet availability of prescription pharmaceutical to the public. Ann Intern Med 1999; 131: 830-3.
19. Eysenbach G. Online prescribing of sildanefil (Viagra®) on the World Wide Web. J Med Internet Res 1999; 1: e10. http://www.jmir.org/1999/2/e10/.
20. StatMarket Search Engine Ratings of July 17 2000. Available at: URL http://www.searchenginewatch.com/reports/statmarket.html. Accessed May 15 2001.
21. Concato J, Feinstein AR, Holford TR. The risk of determining risk with multivariable models. Ann Intern Med 1993; 118: 201-10.
22. Electronic Orange Book Approved Drug Products. Food and Drug Administration. Available at: URL http://www.fda.gov/cder/ob/default.htm.
23. Gelbe Liste Pharmindex MediMedia GmbH. Available at: URL http://www.gelbe-liste.de/.
24. Stockley IH. Drug Interactions, a Source Book of Adverse Interactions, Their Mechanimsms, Clinical Importance and Management, 5th edn. London: The Pharmaceutical Press, 1999.
25. Merry C, Barry MG, Ryan M, Tjia JF, Hennessy M, Eagling VA, Mulcahy F, Back DJ. Interaction of sildenafil and indinavir when co-administered to HIV-positive patients. AIDS 1999; 13: F101-F107.
26. Muirhead GJ, Wulff MB, Fielding A, Kleinermans D, Buss N. Pharmacokinetic interactions between sildenafil and saquinavir/ ritonavir. Br J Clin Pharmacol 2000; 50: 99-107.
27. Hyland R, Roe EG, Jones BC, Smith DA. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil. Br J Clin Pharmacol 2001; 51: 239-48.
28. Warrington JS, Shader RI, von Moltke LL, Greenblatt DJ. In vitro biotransformation of sildenafil (Viagra): identification of human cytochromes and potential drug interactions. Drug Metab Dispos 2000; 28: 392-7.
29. Abbott VP. Web page quality: can we measure it and what do we find? A report of exploratory findings. J Public Health Med 2000; 22: 191-7.
30. Griffiths KM, Christensen H. Quality of web based information on treatment of depression: cross sectional survey. Br Med J 2000; 321: 1511-15.
31. Fallis D, Frické M. Indicators of Accuracy of Consumer Health Information on the Internet: a Study of Indicators Relating to Information for Managing Fever in Children in the Home. J Am Med Inform Assoc 2002; 9: 73-9.