Demographic heterogeneity explains age-specific patterns of genetic variance in mortality rates

Experimental Gerontology

Volumn 39, Issue 1, 2004, Pages 25-30

  Service, Philip M ^a  

^a NORTHERN ARIZONA UNIVERSITY   (United States)

Author keywords

Ageing; Binomial sampling; Drosophila melanogaster; Genetic variance; Gompertz function; Heterogeneity theory; Mortality rate variance

Indexed keywords

AGE; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DROSOPHILA MELANOGASTER; EVALUATION; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; SAMPLING; SIMULATION;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0346687717     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2003.09.014     Document Type: Article

References (7)

1. de Grey A.D.N.J. Overzealous maximum-likelihood fitting falsely convicts the slope heterogeneity hypothesis. Exp. Gerontol. 38:2003;921-923.
2. Mueller L.D., Drapeau M.D., Adams C.S., Hammerle C.W., Doyal K.M., Jazayeri A.J., Ly T., Beguwala S.A., Mamidi A.R., Rose M.R. Statistical tests of demographic heterogeneity theories. Exp. Gerontol. 38:2003;373-386.
3. Pletcher S.D., Curtsinger J.W. The influence of environmentally induced heterogeneity on age-specific genetic variance for mortality rates. Genet. Res. 75:2000;321-329.
4. Pletcher S.D., Houle D., Curtsinger J.W. Age-specific properties of spontaneous mutations affecting mortality in Drosophila melanogaster. Genetics. 148:1998;287-303.
5. Promislow D.E.L., Tatar M., Khazaeli A.A., Curtsinger J.W. Age-specific patterns of genetic variance in Drosophila melanogaster. I. Mortality. Genetics. 143:1996;839-848.
6. Service P.M. Heterogeneity in individual mortality risk and its importance for evolutionary studies of senescence. Am. Nat. 156:2000;1-13.
7. Service P.M. Stress resistance, heterogeneity, and mortality plateaus: a comment on Drapeau et al. Exp. Gerontol. 35:2000;1085-1087.