Efficiently detecting polymorphisms during the fragment assembly process

Bioinformatics

Volumn 18, Issue , 2002, Pages S294-S302

  Fasulo, Daniel ^a   Halpern, Aaron ^a   Dew, Ian ^a   Mobarry, Clark ^a  

^a CELERA GENOMICS   (United States)

Author keywords

Polymorphism; Shotgun sequencing; Whole genome assembly

Indexed keywords

DNA FRAGMENT;

ALGORITHM; ARTICLE; CONSENSUS SEQUENCE; DNA SEQUENCE; EVALUATION; GENE EXPRESSION PROFILING; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENETICS; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEQUENCE ALIGNMENT; VALIDATION STUDY; CONFERENCE PAPER; GENOMIC FRAGMENT; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ALGORITHMS; BASE SEQUENCE; CONSENSUS SEQUENCE; DNA FRAGMENTATION; GENE EXPRESSION PROFILING; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; VARIATION (GENETICS);

EID: 0346605568     PISSN: 13674803     EISSN: None     Source Type: Journal    
DOI: 10.1093/bioinformatics/18.suppl_1.S294     Document Type: Article

References (8)

1. Adams, M.D., Celniker, S.E. et al. (2000) The genome sequence of Drosophila Melanogaster. Science, 287, 2185-2195.
2. Aho, A., Sethi, R. and Ullman, J. (1986) Compilers: Principles, Techniques, and Tools. Addison Wesley.
3. Altschul, S.R, Gish, W., Miller, W., Myers, E.W., Lipman, D. (1990) Basic local alignment search tool. J. Mol. Biol., 215, 403-410.
4. Myers, E. (1995) Toward simplifying and accurately formulating fragment assembly. J. Comp. Biol., 2, 275-290.
5. Myers, E. et al. (1995) Toward simplifying and accurately formulating fragment assembly. J. Comp. Biol., 2, 275-290.
6. Needleman, S.B. and Wunsch, C.D. (1970) A general method applicable to thesearch for similarities in the amino acid sequences. J. Mol. Biol., 48, 443-453.
7. Sutton, G., White, O. and Kerlavage, A. (1995) TIGR assembler: A new tool for assembling large shotgun sequencing projects. Genome Science and Technology, 1, 9-19.
8. Venter, J.C., Adams, M.D., Myers, E.W. et al. (2001) The sequence of the human genome. Science, 291, 1304-1351.