Polymer conjugates with anticancer activity

Advances in Polymer Science

Volumn 122, Issue , 1995, Pages 55-123

  Putnam, D ^a   Kopecek J ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0346551010     PISSN: 00653195     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3540587888_14     Document Type: Article

References (361)

1. Ehrlich P (1906) Studies in immunity. Plenum Press, New York
2. De Duve C. DeVarsy Th, Poole B, Trouet A, Tulkens P, Van Hoof F (1974) Biochem Pharmacol 23: 2495
3. Jatzkewitz H (1954) Hoppe-Seyler's Z Physiolog Chem 297: 149
4. Morell AG, Irvine RA, Sternlieb J, Scheinberg IM, Ashwell G (1968) J Biol Chem 243: 155
5. Ringsdorf H (1975) J Polym Sci Polym Symp 51: 135
6. Zee-Cheng RKY, Cheng CC (1989) Meth and Find Exp Clin Pharmacol 11: 439
7. Papahadjopoulos D, Allen T, Gabizon A, Mayhew E, Matthay K, Huang SK, Lee KD, Woodle MC, Lasic DD, Redemann C. Martin FJ (1991) Proc Natl Acad Sci USA 88: 11460
8. Couvreur P, Roblot-Treupel L, Poupon MF, Brasseur F, Puisieux F (1990) Adv Drug Deliv Rev 5: 209
9. Wright JJ Illum L (1992) in: Donbrow M (ed) Microcapsules and nanoparticles in medicine and pharmacy, CRC Press, Boca Raton, p 281
10. Pastan I, Chaudhary VK, FitzGerald DJ (1992) Ann Rev Biochem 61: 331
11. Debruyne FM, Denis L, Lunglmeyer G, Mahler C, Newling DW, Richards B (1988) J Urol 140: 775
12. Krinick NL, Kopeček J (1991) in: Juliano RL (ed) Targeted drug delivery. Springer, Berlin, p 105 (Handbook of experimental pharmacology, Vol 100)
13. Duncan R (1992) Anti-Cancer Drugs 3: 175
14. Seymour LW (1992) Crit Rev Ther Drug Carrier Syst 9: 135
15. Maeda H, Seymour LW, Miyamoto Y (1992) Bioconjugate Chem 3: 351
16. Sezaki H, Takakura Y, Hashida M (1989) Adv Drug Delivery Rev 3: 247
17. Hoes CJT, Feijen J (1989) in: Roerdink FDH, Kroon AM (eds) Drug carrier systems, John Wiley, New York, p 57
18. Kopeček J Duncan R (1987) J Controlled Rel 6: 315
19. Lloyd JB (1987) in: Johnson P, Lloyd-Jones JG (eds) Drug delivery systems fundamentals, Ellis Horwood, p 95
20. Duncan R. Kopeček J (1984) Adv Polym Sci 57: 51
21. Duncan R, Cable HC, Rejmanová P, Kopeček J, Lloyd JB (1984) Biochim Biophys Acta 799: 1
22. McCormick LA, Seymour LCW, Duncan R, Kopeček J (1986) J Bioact Comp Polym 1: 4
23. Krinick NL, Říhová B, Ulbrich K, Strohalm J, Kopeček J (1990) Makromol Chem 191: 839
24. Říhová B, Kopečková P, Strohalm J, Rossmann P, Větvička V, Kopeček J (1988) Clin Immunol Immunopathol 46: 100
25. McGraw TE, Maxfield FR (1991) in: Juliano RL (ed) Targeted drug delivery. Springer, Berlin, p 11 (Handbook of experimental pharmacology, Vol 100)
26. Kopeček J (1984) Biomaterials 5: 1984
27. Kopeček J (1990) J Controlled Rel 11: 279
28. Willner D, Trial PA, Hofstead SJ, King HD, Lasch SJ, Braslawsky GR, Greenfield RS, Kaneko T, Firestone RA (1993) Bioconjugate Chem 4: 521
29. Shen WC, Ryser HJP (1981) Biochem Biophys Res Commun 102: 1048
30. Shen WC, Ryser HJP, LaManna L (1985) J Biol Chem 260: 10905
31. Feener EP, Shen WC, Ryser HJP (1990) J Biol Chem 265: 18780
32. Thorpe PE, Wallace PM, Knowless PP, Relf MG, Brown ANF, Watson GJ, Knyba RE, Wawrzynczak EJ, Blakey DC (1987) Cancer Res 47: 5924
33. Goddard P, Petrak K (1989) J Bioact Compat Polym 4: 372
34. Chiu HC, Kopečková P, Deshmane S, Kopeček J (1994) J Controlled Rel., to be submitted
35. Chiu HC, Koňák Č, Kopečková P, Kopeček J (1994) J Bioact Compat Polymers, in press
36. Duncan R, Seymour LW, O'Hare KB, Flanagan PA, Wedge S, Hume IC, Ulbrich K, Strohalm J, Subr V, Spreafico F, Grandi M, Ripamonti M, Farao M, Surato A (1992) J Controlled Rel 19: 331
37. O'Hare KB, Duncan R, Strohalm J, Ulbrich K, Kopečková P (1993) J Drug Targeting 1: 217
38. Duncan R, Hume IC, Yardley HJ, Flanagan PA, Ulbrich K, Šubr V, Strohalm J (1991) J Controlled Rel 16: 121
39. Duncan R, Kopečková-Rejmanová P, Strohalm J, Hume I, Cable HC, Pohl J, Lloyd JB, Kopeček J (1987) Br J Cancer 55: 165
40. Duncan R, Kopečková P, Strohalm J. Hume IC, Lloyd JB, Kopeček J (1988) Br J Cancer 57: 147
41. Říhová B, Kopeček J (1985) J Controlled Rel 2: 289
42. Krinick NL, Sun Y, Joyner D, Spikes JD, Straight RC, Kopeček J (1994) J Biomat Sci Polym Ed., 5: 303
43. Řihová B, Krinick NL, Kopeček J (1993) J Controlled Rel 25: 71
44. Hoes CJT, Potman W, van Heeswijk WAR, Mud J, de Grooth BG, Greve J, Feijen J, (1985) J Controlled Rel 2: 205
45. Hoes CJT, Grootoonk J, Duncan R, Hume IC, Bhakoo M, Bouma JMW, Feijen J, (1993) J Controlled Rel 23: 37
46. Hurwitz E, Stancovaki I, Wilchek M, Shouval D, Takahashi H, Wands JR, Sela M, (1990) Bioconjugate Chem 1: 285
47. Abraham A, Nair MG, Kisliuk RL, Gaumont Y, Galivan J (1990) J Med Chem 33: 711
48. Yokoyama M (1989) PhD Thesis, University of Tokyo p 172
49. Yokoyama M, Okano T, Sakurai Y, Ekimoto H, Shibazaki C, Kataoka K (1991) Cancer Res 51: 3229
50. Tanaka T, Kaneo Y, Iguchi S (1991) Bioconjugate Chem 2: 261
51. Ohkawa K, Hatano T, Tsukada Y, Matsuda M (1993) Br J Cancer 67: 274
52. Song Y, Onishi H, Nagai T (1993) Biol Pharm Bull 16: 48
53. Noguchi A, Takahashi T, Yamaguchi T, Kitamura K, Takakura Y, Hashida M, Sezaki H (1992) Bioconjugate Chem 3: 132
54. Shih LB, Goldenberg DM, Xuan H, Lu H, Sharkey RM, Hall TC (1991) Cancer Res 51: 4192
55. Trouet A, Jolies G (1984) Seminars in Oncol. 11 (Suppl 3): 64
56. Oda T, Sato F, Yamamoto H, Akagi M, Maeda H (1989) Anticancer Res 9: 261
57. Konno T, Maeda H (1987) in: Okada K, Ishak KG (eds) Neoplasma of the Liver, Springer, New York, p 343
58. Hirano T, Ringsdorf H, Zaharko DS (1980) Cancer Res 40: 2263
59. Seymour LW (1991) J Bioact Compat Polym 6: 178
60. Ambrose EJ, Easty DM, Jones PCT (1958) Br J Cancer 12: 439
61. McGuire JJ, Russell CA (1990) Leukemia 4: 48
62. Larsen B, Thorling EB (1969) Acta Path Microbiol Scandinav 75: 229
63. Saiki I, Murata K, Matsuno K. Ogawa R, Nishi N, Tokura S, Azuma I (1990) Jpn J Cancer Res 81: 660
64. Saiki I, Murata J, Kakajima M, Tokura S, Azuma I (1990) Cancer Res 50: 3631
65. Zaharko DS, Corey JM (1984) Cancer Treat Rep 68: 1255
66. Ardalan B, Pagel GE (1986) Cancer Res 46: 5473
67. Rosenblum MG. Hortobagyi GN (1986) Cancer Chemother Pharmacol 18: 247
68. Bocci V (1987) Pharmac Ther 34: 1
69. Thomas H (1992) Drugs of today 28: 311
70. Wada H, Imamura I, Sako M, Katagiri S, Tarui S, Nishimura H, Inada Y (1990) Ann N Y Acad Sci, 613: 95
71. Fuertges F, Abuchowski A (1990) J Controlled Rel 11: 139
72. Delgado C, Francis GE, Fisher D (1992) Crit Rev Ther Drug Carrier Syst 9: 249
73. Katre NV, Knauf MJ, Laird WJ (1987) Proc Natl Acad Sci USA 84: 1487
74. Chiu HC, Zalipsky S, Kopečková P, Kopeček J (1993) Bioconjugate Chem 4: 290
75. Wang QC, Pai LH, Debinski W, FitzGerald DJ, Pastan I (1993) Cancer Res 53: 4588
76. Kyriadikis DA, Tsirka SAE, Tsavdaridis IK, Iliadis SN, Kortsaris AH (1990) Mol Cell Biochem 96: 137
77. Ashihara Y, Kono T, Yamazaki S, Inada Y (1978) Biochem Biophys Res Comm 83: 385
78. Hershfield MS, Buckley RH, Greenberg ML, Melton AL, Shiff R, Hatem C, Kurtzberg J, Marken ML, Kobayashi RH, Hobayashi AL, Abuchowski A (1987) N Engl J Med 316: 589
79. Davis S, Abuchowski A, Park YK, Davis FF (1981) Clin Exp Immunol 46: 649
80. Beauchamp CO, Gonias SL, Menapace DP, Pizzo SV (1983) Analytical Biochem 131: 25
81. Pyatak PS, Abuchowski A, Davis FF (1980) Res Comm Chem Pathol Pharmacol 29: 113
82. Veronese FM, Largajolli R, Boccu E, Banassi CA, Shiavon O (1985) Appl Biochem Biotechnol 11: 141
83. Nishimura H, Ashihara Y, Matsushima A, Inada Y (1979) Enzyme 24: 261
84. Katre NV, Knauf MJ, Laird WJ (1987) Proc Natl Acad Sci USA 84: 1487
85. Rajagopalan S, Gonias SL, Pizzi SV (1985) J Clin Invest 75: 413
86. Iwashita Y, Yabuki A, Yamaji KY, Iwasaki K, Okami T, Hirata C, Kosaka K (1988) Biomat Art Cells Art Org 16: 271
87. Tanaka H, Sateke-Ishikawa R, Ishikawa M, Matsuki S, Asano K (1991) Cancer Res 51: 3710
88. Zalipsky S, Lee C (1992) in: Harris JM (ed) Poly (ethylene glycol) chemistry: Biotechnical and biomedical applications, Plenum, New York, p 347
89. Ingham KC (1984) Methods Enzymol. 104: 351
90. Topchieva IN (1980) Russ Chem Rev 49: 260
91. Andrade JD, Nagaoka S, Cooper S, Okano T, Kim SW (1987) ASAIO J 10: 75
92. Lee JH, Kopeček J, Andrade JD (1989) J Biomed Mater Res 23: 351
93. Lee JH, Kopečková P. Kopeček J, Andrade JD (1990) Biomaterials 11: 455
94. Poznansky MJ, Shandling M, Salkie MA, Elliott, J, Lau E (1982) Cancer Res 42: 1020
95. Lääne A, Aaviksaar A, Haga M, Chytrý V, Kopeček J (1985) Makromol Chem Suppl 9: 35
96. Kamei S, Kopeček J (1995) Pharmaceutical Res, in press
97. Takei YG, Aoki T, Sanui K, Ogata N, Okano T, Sakurai Y (1993) Bioconjugate Chem 4: 42
98. Takei YG, Aoki T, Sanui K, Ogata N, Okano T, Sakurai Y (1993) Bioconjugate Chem 4: 341
99. Ito Y, Kotoura M, Chung DJ, Imanishi Y (1993) Bioconjugate Chem 4: 358
100. Drobnik J, Rypáček F (1984) Adv Polym Sci 57: 1
101. Drobnik, (1989) Adv Drug Deliv Rev 3: 229
102. Kopeček J (1982) in: Benoit H, Rempp P (eds) IUPAC macromolecules, Pergamon, Oxford. p 305
103. Kopeček J, Duncan R (1987) in: Illum L, Davis SS (eds) Polymers in controlled drug delivery, John Wright, Bristol, p 152
104. Joyner WL, Kern DF (1990) Adv Drug Deliv Rev 4: 319
105. Pitha J (1980) in: Donaruma IG, Ottenbrite RM, Vogl D (eds) Anionic polymeric drugs. Wiley, New York, p 277
106. Petrak K, Goddard P (1989) Adv Drug Deliv Rev 3: 191
107. Maeda H, Matsumura Y (1989) Crit Rev Ther Drug Carrier Syst 6: 193
108. Senger DR, Galli SJ, Dvorak AM, Perruzzi CA, Harvey VS, Dvorak HF (1983) Science 219: 983
109. Dvorak HF, Nagy JA, Dvorak JT, Dvorak AM (1988) Am J Pathol 133: 95
110. Nugent LJ, Jain RK (1984) Am J Physiol 246: H129
111. Matsumura Y, Maeda H (1986) Cancer Res 6: 6387
112. Magerstadt M, Antibody conjugates and malignant disease, CRC Press, Boca Raton, FL, 1991
113. Seymour LW, Duncan R, Kopečková P, Kopeček J (1987) J Bioact Compat Polym 2: 97
114. Bos E, Boon P, Kaspersen F, McCabe R (1991) J Controlled Rel 16: 101
115. Flavell DJ, Cooper S, Morland B, French R, Flavell SU (1992) Br J Cancer 65: 545
116. Fanger MW, Morganelli PM, Guyre PM (1992) Crit Rev Immunol 12: 101
117. Baxter LT, Jain RK (1991) Microvascular Res 41: 5
118. Dilman RO (1990) Antibody, Immunoconjug Radiopharm 3: 1
119. Yokota T, Milenic DE, Whitlow M, Schlom J (1992) Cancer Res 52: 3402
120. Wright A, Shin SU, Morrison SL (1992) Crit Rev Immunol 12: 125
121. LoBuglio AF, Wheeler RH, Trang J, Haynes A, Rogers K, Harvey EB, Sun L, Ghrayeb J, Khazaeli MB (1989) Proc Natl Acad Sci USA 86: 4220
122. Hale G, Clark MR, Marcus R, Winter G, Dyer MJS, Philips JM, Reichmann L, Waldmann H (1988) Lancet p 1394
123. Trail PA, Willner D, Lasch SJ, Henderson AJ, Hofstead S, Casazza AM, Firestone RA, Hellstrom I, Hellstrom KE (1993) Science 261: 212
124. Šprincl L, Exner J, Štěrba O, Kopeček J (1976) J Biomed Mater Res 10: 953
125. Seymour LW, Duncan R, Strohalm J, Kopeček J (1987) J Biomed Mater Res 21: 1341
126. Arturson G. Granath K, Thoren L, Wallenius G (1964) Acta Chir Scand 127: 543
127. Yamaoka T, Tabata Y, Ikada Y (1993) Drug Delivery 1: 75
128. Kopeček J (1981) in: Williams DF (ed) Systemic aspects of biocompatibility, Vol II, CRC Press, Boca Raton, p 159
129. Hespe W, Meier AM, Blakwater YJ (1977) Drug Res 27: 1158
130. Takakura Y, Fujita T, Hashida M, Sezaki H (1990) Pharmaceutical Res 7: 339
131. Duncan R, Pratten MK, Cable HC, Ringsdorf H, Lloyd JB (1981) Biochem J 196: 49
132. Ulbrich K, Koňák Č, Tuzar Z, Kopeček J (1987) Makromol Chem 188: 1261
133. Nukui M, Hoes K, van den Berg H, Feijen J (1991) Makromol Chem 192: 2925
134. Koňák Č, Kopečková P, Kopeček J (1992) Macromolecules 25: 5451
135. Yokoyama M, Inoue S, Kataoka K, Yui N, Okano T, Sakurai Y, (1989) Makromol Chem 190: 2041
136. Yokoyama M, Kwon GS, Okano T, Sakurai Y, Ekimoto, Okamoto K, Mashiba H, Seto T, Kataoka K (1993) Drug Delivery 1: 11
137. Trouet A, Masquelier M, Baurain R, Deprez-de Campeneere D (1982) Proc Natl Acad Sci USA 79: 626
138. Schechter B, Neumann A, Wilchek M, Arnon R (1989) J Controlled Rel 10: 75
139. Howe-Grant ME, Lippard SJ (1980) in: Sigel H (ed) Metal ions in biological systems, Vol 11, Marcel Dekker, New York, p 63
140. Kopeček J (1977) Polymers in Medicine (Wroclaw) 7: 191
141. Říhová B, Strohalm J, Plocová D, Ulbrich K (1990) J Bioact Compat Polym 5: 249
142. Obereigner B, Burešová M, Vrána A, Kopeček J (1979) J Polym Sci Polym Symp. 66: 41
143. Ouchi T, Fujie H, Jokei S, Sakamoto Y. Chikashita H, Inoi T, Vogl O (1986) J Polym Sci Part A: Polym Chem 23: 2059
144. Ozaki S, Ohnishi J, Watanabe Y, Nohda T, Nagase T, Akiyama T, Uehara N, Hoshi A (1989) Polymer J 21: 955
145. Giammona G, Giannola LI, Carlisi B, Bajardi ML (1989) Chem, Pharm Bull 37: 2245
146. Yang F, Zhuo R (1990) Polymer J 22: 572
147. Zunino F, Pratesi G, Micheloni A (1989) J Controlled Rel 10: 65
148. Nagy A, Szoke B, Schally AV (1993) Proc Natl Acad Sci USA 90: 6373
149. Schacht E (1987) in: Illum L, Davis SS (eds) Polymers in drug delivery. Wright, Bristol, p 131
150. Carlsson J, Drevin H, Axen R (1978) Biochem J 173: 723
151. Kitagawa T, Shimozono T, Aikawa T, Yoshida T, Nishimura H (1981) Chem Pharm Bull 29: 1130
152. Kitagawa T, Aikawa T (1976) J Biochem 79: 233
153. Henkin J (1977) J Biol Chem 252: 4293
154. Webb RR II, Kancko E (1990) Bioconjugate Chem 1: 96
155. Vanin EF, Ji TH (1981) Biochemistry 20: 6754
156. Trommer WE, Kolkenbrock H, Pfleiderer G (1975) Hoppe-Seyler's Z Physiol Chem 356: 1455
157. Wong SS (1993) Chemistry of protein conjugation and crosslinking, CRC Press, Boca Raton, Florida
158. Pietersz GA (1990) Bioconjugate Chem 1: 89
159. Brinckley M (1992) Bioconjugate Chem 3: 2
160. Persiani S, Yeung A, Shen W-C, Kennedy A (1991) Carcinogenesis 12: 1149
161. Alam F, Soloway A, Barth RF, Mafune N, Adams DM, Knoth WH (1989) J Med Chem 32: 2326
162. Chytrý V, Kopeček J, Leibnitz E, O'Hare K, Scarlett L, Duncan R (1987) New Polym Mater 1: 21
163. Duncan R, Kopeček J, Rejmanová P, Lloyd JB (1983) Biochim Biophys Acta 755: 518
164. Pietersz GA, Cunningham Z, McKenzie FC (1988) Immunol Cell Biol 66: 43
165. Rodwell JD, Alvarez VL, Lee C, Lopes AD, Goers JWF, King HD, Powsner HJ, McKearn TJ (1986) Proc Natl Acad Sci USA 83: 2632
166. O'Shannesy DJ (1990) J Chromatography 510: 13
167. Mann JS, Huang JC, Keana JFW (1992) Bioconjugate Chem 3: 154
168. Kato Y, Umemoto N, Kayama Y, Fukushima H, Takeda Y, Hara T, Tsukada Y (1984) J Med Chem 27: 1602
169. Kopeček J, Rejmanová P, Strohalm J, Ulbrich K, Říhová B, Chytrý V, Lloyd JB, Duncan R (1991) US Patent 5,037,883
170. Matzku S, Moldenhauer G, Kalthoff H, Canevari S, Colnaghi M, Schuhmacher J, Bihl H (1990) Br J Cancer 62 Suppl X: 1
171. Bagshawe KD (1989) Br J Cancer 60: 275
172. Senter PD, Wallace PM, Svensson HP, Vrudhula VM, Kerr DE, Hellstrom J, Hellstrom KE (1993) Bioconjugate Chem 4: 3
173. Bagshawe KD, Sharma SK, Springer CJ, Antoniw P, Rogers GT, Burke PJ, Melton R, Sherwood R (1991) Antibody Imm Radiopharm 4: 915
174. Cowan JD, Von Hoff DD (1987), in: Muggia FM, Rozencweig M (eds) Clinical evaluation of antitumor therapy, Nijhoff, Boston, p 33
175. Sheldon K, Marks A, Baumal R (1989) Anticancer Res 9: 637
176. Goff BA, Bamberg M, Hasan T (1991) Cancer Res 51: 4762
177. Říhová B, Bilej M, Větvička V, Ulbrich K, Strohalm J, Kopeček J, Duncan R (1989) Biomaterials 10: 335
178. Hurwitz E, Kashi R, Arnon R, Wilchek M, Sela M (1985) J Med Chem 28: 137
179. Smyth MJ, Pietersz GA, McKenzie IFC (1987) Cancer Res 47: 62
180. Aboud-Pirak E, Hurwitz E, Bellot F, Schlessinger J, Sela M (1989) Proc Natl Acad Sci USA 86: 3778
181. Dillman RO, Shawler DL, Johnson DE, Meyer DL, Koziol JA, Frincke JM (1986) Cancer Res 46: 4886
182. Pietersz GA, Smyth MJ, McKenzie IFC (1988) Cancer Res 48: 926
183. Yeh MY, Roffler SR, Yu MH (1992) Int J Cancer 51: 274
184. Kanellos J, Pietersz GA, Cunningham Z, McKenzie IFC (1987) Immunol. Cell Biol 65: 483
185. Kanellos J, Pietersz GA, McKenzie IFC (1985) J Natl Cancer Inst 75: 319
186. Hurwitz E, Levy R, Maron R, Wilchek M, Arnon R, Sela M (1975) Cancer Res 35: 1175
187. Mosmann T (1983) J Immunol Methods 65: 55
188. Slater TF, Sawyer B, Strauli U (1963) Biochim Biophys Acta 77: 383
189. Shimoyama Y, Kubota T, Watanabe M, Ishibiki K, Abe O (1989) J Surg Oncol 41: 12
190. Suto A, Kubota T, Shimoyama Y, Ishibiki K, Abe O (1989) J Surg Oncol 42: 28
191. Krinick NL, Říhová B, Ulbrich K, Andrade JD, Kopeček J (1988) Proc SPIE 997: 70
192. Kubota T, Yamamoto T. Takahara T, Furukawa T, Ishibiki K, Kitajima M, Shida Y, Nakatsubo H (1992) J Surg Oncol 51: 75
193. Hoogenboom HR, Raus JCM, Volckaert G (1991) Biochim. Biophys Acta 1096: 345
194. Roper PR, Drewinko B (1976) Cancer Res 36: 2182
195. Hamburger AW, Salmon SE (1977) Science 197: 461
196. Scott Jr. CF, Goldmacher VS, Lambert JM, Jackson JV, Malntyre GD (1987) J Natl Cancer Inst 79: 1163
197. Rakestraw SL, Ford WE, Tompkins RG, Rodgers MAJ, Thorpe WP, Yarmush ML (1992) Biotechnol Prog 8: 30
198. Oseroff AR, Ohuoha D, Hasan T, Bommer JC, Yarmush ML (1986) Proc Natl Acad Sci USA 83: 8744
199. Triton TR, Yee G (1982) Science 217: 248
200. Hirano T, Ohashi S, Morimoto S, Tsuda K, Kobayashi T, Tsukagoshi S (1986) Makromol Chem 187: 2815
201. Jones KH, Senft JA (1985) J Histochem Cytochem 33: 77
202. Altman SA, Randers L. Rao G (1993) Biotechnol Prog 9: 671
203. Endo N, Takeda Y, Umemoto N, Kishida K, Watanabe K, Saito M, Kato Y, Hara T (1988) Cancer Res 48: 3330
204. Umemoto N, Kato Y, Endo N, Takeda Y, Hara T (1989) Int J Cancer 43: 677
205. Ovadia M, Hager CC, Oeltmann TN (1990) Anticancer Res 10: 671
206. Youle RJ, Neville Jr, DM (1980) Proc Natl Acad Sci USA 77: 5483
207. Kopeček J, Šprincl L (1974) Polymers in Medicine (Wroclaw) 4: 109
208. Teece R, Fraioli R, De Fabritis P, Sandrelli A, Savarese A, Santoro L, Cuomo M, Natali PG, (1991) Int J Cancer 49: 310
209. Brooks CG, Rees RC, Robins RA (1978) J Immunol Meth 21: 111
210. Van Putten LM (1987), in: Muggia FM, Rozencweig M (eds) Clinical evaluation of antitumor therapy, Nijhoff, Boston p 17
211. Ueda Y, Munechika K, Kikukawa A, Kanöh Y, Yamanouchi K, Yokoyama K (1989) Chem Pharm Bull 37: 1639
212. Goldin A (1966) Cancer Chemotherapy Reports 50: 173
213. Ohya Y, Huang TZ, Ouchi T, Hasegawa K, Tamura J, Kadowaki K, Matsumoto T, Suzuki S, Suzuki M (1991) J Controlled Rel 17: 259
214. Zunino F, Giuliani F, Saui G, Dasdia T, Gambetta R (1982) Int J Cancer 30: 465
215. Pratesi G, Savi G, Pezzoni G, Bellini O, Penco S, Tinelli S, Zunino F (1985) Br J Cancer 52: 841
216. Meyer RM, Quirt IC, Skillings JR, Cripps MC, Bramwell VHC, Weinerman BH, Gospodarowitz MK, Burns BF, Sargeant AM Shepherd LE, Zee, B. Hryniuk WM (1993) N Engl J Med 329: 1770
217. Bernstein A, Hurwitz E, Maron R, Arnon R, Sela M, Wilchek M (1978) J Natl Cancer Inst 60: 379
218. Flanagan PA, Duncan R, Říhová B, Šubr V, Kopeček J (1990) J Bioact Compat Polym 5: 151
219. Maeda H, Matsumoto T, Konno T, Iwai K, Ueda M (1984) J Protein Chem 3: 181
220. Meijer DKF, Jansen RW, Pauwels R, Schols D, deClercq E (1992) 2nd Eur Symp on Controlled Drug Delivery, Noordwijk aan Zee, The Netherlands, April 1-3, Abstracts p 167
221. Meijer DKF, Jansen RW, Molema G (1992) Antiviral Res 18: 215
222. Myers KJ, Ron Y (1992) Pharmaceutical Technology p 26 (January)
223. Sung C, Shockley TR, Morrison PF, Dvorak HF, Yarmush ML, Dedrick RL (1992) Cancer Res 52: 377
224. Anderson DC, Manger R, Schroeder J, Woodle D, Barry M, Morgan AC, Fritzberg AR (1993) Bioconjugate Chem 4: 10
225. Wichterle O, Lím D (1960) Nature 185: 117
226. Wichterle O (1968) US Patent 3,361, 858
227. Šprincl L, Vacík J, Kopeček J, Lím D (1971) J Biomed Mater Res 5: 197
228. Šprincl L, Vacík J, Kopeček J (1973) J Biomed Mater Res 7: 123
229. Kopeček J, Šprincl L, Bažilová H, Vacík J (1973) J Biomed Mater Res 7: 111
230. Šprincl L, Kopeček J, Lím D (1973) Calc Tissue Res 13: 63
231. Kopeček J, Šprincl L, Lím D (1973) J Biomed Mater Res 7: 179
232. Voldřich Z, Tománek Z, Vacík, J Kopeček J (1975) J Biomed Mater Res 9: 675
233. Kopeček J, Bažilová H (1973) Europ. Polym J 9: 7
234. Bohdanecký M, Bažilová H, Kopeček J (1974) Europ Polym J 10: 405
235. Drobnik J, Kopeček J, Labsky J, Rejmanová P, Exner J, Saudek, V, Kálal J (1976) Makromol Chem 177: 2833
236. Kopeček J, Cífková I, Rejmanová P, Strohalm J, Obereigner B, Ulbrich K (1981) Makromol Chem 182: 2941
237. Rejmanová P, Labsky J, Kopeček J (1977) Makromol Chem 178: 2159
238. Kopeček J (1977) Makromol Chem 178: 2169
239. Kopeček J, Rejmanová P (1979) J Polym SCi Poly Symp 66: 15
240. Chytrý V, Vrána A, Kopeček J (1978) Makromol Chem 179: 329
241. Solovskij MV, Ulbrich K, Kopeček J (1983) Biomaterials 4: 44
242. Schechter I, Berger A (1967) Bichem Biophys Res Commun 27: 157
243. Kopeček J, Rejmanová P, Chytrý V (1981) Makromol Chem 182: 79 9
244. Rejmanová P, Obereigner B, Kopeček J (1981) Makromol Chem 182: 1899
245. Ulbrich K, Strohalm J, Kopeček J (1981) Makromol Chem 182: 1917
246. Ulbrich K, Zacharieva EI, Obereigner B, Kopecek J (1980) Biomaterials 1: 199
247. Duncan R, Cable HC, Lloyd JB, Rejmanová P, Kopeček J (1982) Biosci Rep 2: 1041
248. Duncan R, Cable HC Lloyd JB, Rejmanová P, Kopeček J (1983) Makromol Chem 184: 1997
249. Rejmanová P, Pohl J, Baudyš M, Kostka V, Kopeček J (1983) Makromol Chem 184: 2009
250. Šubr V, Kopeček J, Pohl J, Baudyš M, Kostka V (1988) J Controlled Rel 9: 133
251. Rejmanovǎ P, Kopeček J, Duncan R, Lloyd JB (1985) Biomaterials 6: 45
252. Kopeček J, Rejmanová P, Duncan R, Llyod JB (1985) Ann N Y Acad Sci 446: 93
253. Kopeček J (1987) Proc Intern Symp Control Rel Bioactive Mater 14: 125
254. Blow DM (1974) Bayer Symp 5: 473
255. Ulbrich K, Strohalm J, Kopeček J (1986) Makromol Chem 187: 1131
256. Musil D, Zucic D, Turk D, Engh RA, Mayr I, Huber R, Popovic T, Turk V, Towatari T, Katunuma N, Bode W (1991) EMBO J 10: 2321
257. Yamamoto A, Kaji T, Tomoo K, Ishida T, Inoue M, Murata M, Kitamura K (1992) J Mol Biol 227: 942
258. Van den Hamer CJA, Morell AG, Scheiberg IH, Hickman J, Ashwell G (1970) J Biol Chem 245: 4397
259. Ashwell G, Harford J (1982) Annu Rev Biochem 51: 531
260. Duncan R, Lloyd JB, Rejmanová P, Kopeček J (1985) Makromol Chem Suppl 9: 3
261. Duncan R, Seymour LCW, Scarlett L, Lloyd JB, Rejmanová P, Kopeček J (1986) Biochim Biophys Acta 880: 62
262. Wedge SR, Duncan R, Kopečková P (1991) Br J Cancer 63: 546
263. Omelyanenko V, Kopečková P, Rathi RC, Kopeček J (1994) Biochim Biophys Acta to be submitted
264. Duncan R, Hume IC, Kopečková P, Ulbrich K, Strohalm J, Kopeček J (1989) J Controlled Rel 10: 51
265. Seymour L, Ulbrich K, Wedge SR, Hume IC, Strohalm J, Duncan R (1991) Br J Cancer 63: 859
266. Cartlidge SA, Duncan R, Llyod JB, Rejmanová P, Kopeček J (1986) J Controlled Rel 3: 55
267. Goddard P, Williamson I, Brown J, Hutchinson LE, Nicholls J, Petrak K (1991) J Bioact Compat Polym 6: 4
268. Cartlidge SA, Duncan R, Lloyd JB, Kopečková-Rejmanová P, Kopeček J (1987) J Controlled Rel 4: 253
269. Ambler LE, Brookman L, Brown J, Goddard P, Petrak K (1992) J Bioact Compat Polym 7: 233
270. Cartlidge SA, Duncan R, Lloyd JB, Kopečková-Rejmanová P, Kopeček J (1987) J Controlled Rel 4: 265
271. Ulbrich K, Zacharieva EI, Kopeček, J Hume IC, Duncan R (1987) Makromol Chem 188: 2497
272. O'Hare KB, Hume IC, Scarlett L, Chytrý V, Kopečková P, Kopeček J, Duncan R (1989) Hepatology 10: 207
273. Říhová B, Kopeček J, Kopečková-Rejmanov́ P, Strohalm J, Plocová D, Semorádová H (1986) J Chromatogr Biomed Appl 376: 221
274. Říhová B, Větvička V, Strohalm J, Ulbrich K, Kopeček J (1989) J Controlled Rel 9: 21
275. Říhová B, Vereš V, Fornüsek L, Ulbrich K, Strohalm J, Větvička V, Bilej M, Kopeček J (1989) J Controlled Rel 10: 37
276. Seymour LW, Flanagan PA, Al-Shamkani A, Subr V, Ulbrich K, Cassidy J, Duncan R (1991) Select. Cancer Therapeut 7: 59
277. Flanagan PA, Kopečková P, Kopeček J, Duncan R (1989) Biochim Biophys Acta 993: 83
278. Krinick NL, Combination polymeric drugs as anticancer agents, Ph D Thesis, University of Utah, 1992
279. Kopeček J, Krinick NL (1993) US Patent 5,258,453
280. Štěrba O, Paluska E, Jozová O, Špunda J, Nezvalová J, Šprincl L, Kopeček J, Činátl J (1975) Čas Lék Českých 114: 1268
281. Korčáková L, Paluska E, Hašková V, Kopeček J (1976) Z. Immun Forsch 151: 219
282. Paluska E, Činátl J, Korčáková L, Štěrba O, Kopeček J Hrubá A, Nezvalová j, Staněk R (1980) Folia biologica (Prague) 26: 304
283. Štěeba O, Uhlířová Z, Petz R, Viktora L, Jirásek A, Kopeček J (1980) Čas Lék. Českých 119: 994
284. Činátl J, Štěrba O, Paluska E, Polednová V, Kopeček J (1980) Čs Farmacie 29: 134
285. Paluska E, Hrubá A, Štěrba O, Kopeček J (1986) Folia Biologica (Prague) 32: 91
286. Říhová B, Kopeček J, Ulbrich K, Pospíšil M, Mančal P (1984) Biomaterials 5: 143
287. Říhová B, Ulbrich K, Kopeček J, Mančal P (1983) Foila Microbiologica (Prague) 28: 217
288. Říhová B, Kopeček J, Ulbrich K, Chytrý V (1985) Makromol Chem Suppl 9: 13
289. Tlaskalová-Hogenová H, Kopeček J, Ulbrich K, Ryṕaček F, Pospíšil M (1985) Makromol Chem Suppl 9: 137
290. Šimečková J, Říhová B, Plocová D, Kopeček J (1986) J Bioact Compat Polym 1: 20
291. Yeung TK, Hopewell JW, Simmonds RH, Seymour LW, Duncan R, Bellini O, Grandi M, Spreafico F, Strohalm J, Ulbrich K (1991) Cancer Chemother Pharamacol 29: 105
292. Seymour LW, Ulbrich K, Strohalm J, Kopeček J, Duncan R (1990) Biochem Pharmacol. 39: 1125
293. Gu ZW, Spikes JD, Kopečková P, Kopeček J (1993) Collect Czech Chem Commun 58: 2321
294. Bayley H, Gasparro F, Edelson R (1987) Trends Pharmacol Sci 8: 138
295. Cassidy J, Duncan R, Morrison GJ, Strohalm J, Plocová D, Kopeček J, Kaye SB (1989) Biochem Pharmacol 38: 875
296. Gomer CJ, Rucker N, Ferratio A, Wong S (1989) Radiat Res 120: 1
297. Henderson BW, Dougherty TJ (1992) Photochem Photobiol 55: 145
298. Spikes JD (1989) in: Smith KC (ed) The science of photobiology, 2nd ed., Plenum New York, p. 79
299. Kopeček J, Říhová B, Krinick NL (1991) J Controlled Rel 16: 137
300. Kopeček J, (1991) Ann N Y Acad Sci 618: 335
301. Jiang FN, Allison B, Liu D, Levy JG (1992) J Controlled Rel 19: 41
302. Wöhrle D, Krawczyk G, Paliuras M (1988) Makromol Chem 189: 1013
303. Peterson MC et al. (1994) in preparation
304. Sata T (1990) Polysaccharide coated liposomes, Ph D Thesis, University of Nagasaki
305. Gregoriadis G (1993) Liposome technology, Vol I-III, 2nd ed., CRC Press, Boca Raton, FL
306. Nässander UK (1991) Liposomes, immunoliposomes, and ovarian carcinoma, PhD Thesis, Unviersity of Utrecht
307. Connor J Huang L (1986) Cancer Res 46: 3431
308. Maeda M, Kumano A, Tirrell DA (1991) Ann New York Acad Sci 618: 362
309. Weinstein JN, Magin RL, Cysyk RL, Zaharko DS (1980) Cancer Res 40: 1388
310. Zou Y, Yamagishi M, Horikoshi I, Ueno M, Gu X, Perez-Soler R (1993) Cancer Res 53. 3046
311. Senior J (1987) Crit Rev Ther, Drug Carrier Syst 3: 123
312. Becker S (1988) Adv Drug Deliv Rev 3: 1
313. Alving CR (1988) Adv Drug Deliv Rev 2: 107
314. Lopez-Berenstein G, Fainstein V, Hopfer R, Mehta K, Sullivan MP, Keating M, Rosenblum MG, Mehta R, Luna M, Hersh EM, Reuben J, Juliano RL, Bodey GP (1985) J Infect Dis 150: 278
315. Sculier JP, Coune A, Meunier F, Brassine C, Laduron C, Hollaert C, Collete N, Heymans C, Klastersky J (1988) Eur J Cancer Clin Oncol 24: 527
316. Sunamoto J, Iwamoto K (1986) Crit Rev Ther Drug Carrier Syst 2: 117
317. Peeters PAM, Storm G, Crommelin DJA (1987) Adv Drug Deliv Rev 1: 249
318. Allen TM, Mehra T, Hansen C, Chin YC (1992) Cancer Res 52: 2431
319. Allen TM (1993) NATO ASI "Targeting of Drugs: Advances in Systems Constructs", Cape Sounion Beach, Greece, June 24 - July 5, 1993, Abstracts
320. Torchilin VP, Trubetskoy VS, Papisov MI, Bogdanov AA, Omelyanenko VG, Narula J, Khaw BA (1993) Proc Intern Symp Control Rel Bioact Mater 20: 194
321. Cowens JW, Creaven PJ, Greco WR, Brenner DE, Tung Y, Ostro M, Pilkiewicz F. Ginsberg R, Petrelli N (1993) Cancer Res 53: 2796
322. Nabel GJ, Nabel EG, Yang ZY, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D. Chang AE (1993) Proc Natl Acad Sci USA 90: 11307
323. Douglas SJ, Davis SS, Illum L (1987) Crit Rev Ther Drug Carrier Syst 3: 233
324. Couvreur P, Vauthier C (1991) J Controlled Rel 17: 187
325. Birrenbach G, Speiser P (1976) J Pharm Sci 65: 1763
326. Kreuter J, Speiser P (1976) J Pharm Sci 65: 1424
327. Lenaerts V, Couvreur P, Christiaens-Leyh D, Joiris E, Roland M, Rollman B, Speiser P (1984) Biomaterials 5: 65
328. Verdun C, Brasseur F, Vranckx H, Couvreur P, Roland M (1990) Cancer Chemother Pharmacol 26: 13
329. Illum L, Jones PDE, Baldwin RW, Davis SS (1984) J Pharmacol Exp Ther 230: 733
330. Douglas SJ, Davis SS, Illum L (1986) Int J Pharm 34: 145
331. Müller BG, Kissel T (1993) Pharm Pharmacol Lett 3: 67
332. Donbrow M (1992) Microcapsules and nanoparticles in medicine and pharmacy, CRC Press, Boca Raton, FL
333. Pfeifle CE, Howell SB, Ashburn WL, Barone RM, Bookstein JJ (1986) Cancer Drug Deliv 3: 1
334. Edman P, Sjöholm I (1992) in: Donbrow M (ed) Microcapsules and nanoparticles in medicine and pharmacy, CRC Press, Boca Raton, FL, p 265
335. Juliano RL (1988) Adv Drug Del Rev 2: 31
336. Illum L, Davis SS (1984) FEBS Lett 167: 79
337. Illum L, Davis SS, Muller RH, Mak E, West P (1987) Life Sci 40: 367
338. Illum L, Davis SS (1987) Life Sci 40: 1553
339. Moghimi SM, Illum L, Davis SS (1990) Crit Rev Ther Drug Carrier Syst 7: 187
340. Harper GR, Davies MC, Davis SS, Tadros ThF, Taylor DC, Irving MP, Waters JA (1991) Biomaterials 12: 695
341. Okada H, Heya T, Ogawa Y, Shimamoto T (1988) J Pharmacol Exp Therap 244: 744
342. Ogawa Y, Okada H, Heya T, Shimamoto T (1989) J Pharm Pharmacol 41: 439
343. Okada H, Inoue Y, Heya T, Ueno H, Ogawa Y, Toguchi H (1991) Pharmaceutical Res 8: 787
344. Říhová B, Jegorov A, Strohalm J, Matha V, Rossmann, P, Fornůsek L, Ulbrich K (1992) J Controlled Rel 19: 25
345. Ogawa Y, Yamamoto M, Takada S, Okada H, Shimamoto T (1988) Chem Pharm Bull 36: 1502
346. Neville Jr DM, Scharff J, Srinivasachar K (1993) J Controlled Rel 24: 133
347. Sung C, Wilson D, Youle RJ (1991) J Biol Chem 266: 14159
348. FitzGerald D, Pastan I (1989) J Natl Cancer Inst 81: 1455
349. Wawrzynczak EJ (1991) Br J Cancer 64: 624
350. Byers VS, Rodvien R, Grant K, Durrant LG, Hudson KH, Baldwin RW, Scannon PJ (1989) Cancer Res 49: 6153
351. Vitetta ES, Stone M, Amlot P, Fay J, May R, Till M, Newman J, Clark P, Cunningham D, Ghetie V, Uhr JW, Thorpe PE (1991) Cancer Res 51: 4052
352. Oratz R, Speyer JL, Wernz JC, Hochster H, Meyers M, Mischak R, Spitler LE (1990) J Biol Respons Mod 9: 345
353. Kreitman RJ, FitzGerald D, Pastan I (1992) Int J Immunopharmac 14: 465
354. Pastan I, FitzGerald DJ (1991) Science 254: 1173
355. FitzGerald D, Pastan I (1993) NATO ASI "Targeting of Drugs: Advances in Systems Constructs", Cape Sounion Beach, Greece June 24 - July 5, 1993, Abstracts
356. Hinman LM, Hamann PR, Wallace R, Menendez AT, Durr FE, Upeslacis J (1993) Cancer Res
357. Chari RVJ, Martell BA, Gross JL, Cook SB, Shah SA, Blättler WA, McKenzie SJ, Goldmacher VS (1992) Cancer Res 52: 127.
358. Lee MD, Dunne TS, Chang CC, Siegal MM, Morton GO, Ellestad GA, McGahren WJ, Borders DB (1992) J Am Chem Soc 114: 985
359. Anderson WF (1994) Human Gene Therapy 5: 1
360. Degols G, Machey P, Leonetti JP, Leserman L, Lebleu B (1992) in: Murray JAH (ed) Antisense RNA and DNA, Wiley-Liss, New York, p 255
361. Stein CA, Cheng YC (1993) Science 261: 1004