Overview of the Pharmacokinetic Properties of Fluoroquinolones in Companion Animals

Compendium on Continuing Education for the Practicing Veterinarian

Volumn 21, Issue SUPPL. 12, 1999, Pages 7-11

  Kietzmann, M ^a  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0346525979     PISSN: 01931903     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (21)

1. Brown SA: Fluoroquinolones in animal health. J Vet Pharmacol Ther 19:1-14, 1996.
2. Kroker R, Löscher W, Simunek J, et al: Chemotherapie bakterieller Infektionen, in Frey HH, Löscher W (eds): Lehrbuch der Pharmakologie und Toxikologie für die Veterinärmedzin. Stuttgart, Enke Verlag, 1996, pp 454-508.
3. Bishop Y: The Veterinary Formulary, ed 4. London, Pharmaceutical Press, 1998, pp 160-163.
4. Hussy P, Maass G, Tummler B: Effect of 4-quinolones and novobiocin on calf thymus DNA polymerase primase complex, topoisomerases I and II, and growth of mammalian lymphoblasts. Antimicrob Agents Chemother 29: 1073-1078, 1986.
5. Küng K, Wanner M: Einfluss zweier verschiedener Futter auf die Pharmakokinetik von oral appliziertem Baytril® (Enrofloxacin) beim Hund. Kleintierpraxis 38:95-102, 1993.
6. Hawkins EC, Boothe DM, Guinn A, et al: Concentration of enrofloxacin and its active metabolite in alveolar macrophages and pulmonary epithelial lining fluid of dogs. J Vet Pharmacol Ther 21:18-23, 1998.
7. Scheer M: Concentrations of active ingredient in the serum and in tissues after oral and parenteral administration of Baytril®. Vet Med Res 2:104-118, 1987.
8. Meinen JB, McClure JT, Rosin E: Pharmacokinetics of enrofloxacin in clinically normal dogs and mice and drug pharmacodynamics in neutropenic mice with Escherichia coli and staphylococcal infections. Am J Vet Res 56: 1219-1224, 1995.
9. Monlouis JD, DeJong A, Richez P: Plasma pharmacokinetics and urine concentrations after oral administration of enrofloxacin to dogs. J Vet Pharmacol Ther 20(Suppl 1):61-62, 1997.
10. Richez P, Monlouis JD, Dellac B, Daube G: Validation of a therapeutic regimen for enrofloxacin in cats on the basis of pharmacokinetic data. J Vet Pharmacol Ther 20(Suppl 1): 152-153, 1997.
11. McKellar QA: Clinical relevance of the pharmacologic properties of fluoroquinolones. Proceedings of the Second International Veterinary Symposium on Fluoroquinolones. Suppl Campend Contin Educ Pract Vet 18(2):14-21, 1996.
12. DeManuelle TC, Ihrke PJ: Comparison of enrofloxacin skin concentrations in normal dogs and in dogs with pyoderma. Proceedings of the Third International Veterinary Symposium on Fluoroquinolones. Suppl Compend Contin Educ Pract Vet 21(12):49-56, 1999.
13. Tulkens PM: Accumulation and subcellular distribution of antibiotics in macrophages in relation to activity against intracellular activity, in Pass RJ (ed): Ciprofloxacin in Pulmonology. München, Zuckschwerdt Verlag, 1990, pp 12-20.
14. Aucoin DP: Intracellular-intraphagocytic dynamics of fluoroquinolone antibiotics: A comprehensive review. Proceedings of the Second International Veterinary Symposium on Fluoroquinolones. Suppl Compend Contin Educ Pract Vet 18(2):9-13, 1996.
15. Boothe DM: Drug therapy for respiratory tract infections. Orlando, FL, Bayer Selected Proceedings from the 1998 TNAVC, 1998, pp 10-19.
16. Duval JM, Budsberg SC: Cortical bone concentrations of enrofloxacin in dogs. Am J Vet Res 56:188-192, 1995.
17. Kietzmann M, Nolte I: Unpublished results, 1999.
18. Wolfson JS, Hooper DC: Pharmacokinetics of quinolones: Newer aspects. Eur J Clin Microbiol Infect Dis 10:267-274, 1991.
19. Lefebvre HP, Dupouy V, Schneider M, et al: Pharmacokinetics of marbofloxacin in the renal-impaired dog. J Vet Pharmacol Ther 20(Suppl 1):31-32, 1997.
20. Wetzstein HG, DeJong A: In vitro bactericidal activity and postantibiotic effect of fluoroquinolones used in veterinary medicine. Proceedings of the Second International Veterinary Symposium on Fluoroquinolones. Suppl Compend Contin Educ Pract Vet 18(2):22-29, 1996.
21. Boeck A, Boothe DM, Wilkie S: Time course of enrofloxacin and its active metabolite in peripheral leukocytes in dogs. Proceedings of the Third International Veterinary Symposium on Fluoroquinolones. Suppl Compend Contin Educ Pract Vet 21(12):40-43, 1999.