HPA-genotyping and antiplatelet antibodies in female blood donors

Hematology Journal

Volumn 4, Issue 6, 2003, Pages 441-444

  Boehlen, Françoise ^a   Bulla, Oana ^a   Michel, Martine ^a   Reber, Guido ^a   de Moerloose, Philippe ^a  

^a UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Antiplatelet antibodies; Blood donors passive alloimmune thrombocytopenia; HPA genotyping; HPA immunization

Indexed keywords

ALLOANTIBODY; THROMBOCYTE ANTIBODY; THROMBOCYTE ANTIGEN;

ADULT; ALLOIMMUNITY; ANTIBODY SPECIFICITY; ARTICLE; BIOASSAY; BLOOD COMPONENT; BLOOD DONOR; BLOOD TRANSFUSION; CONTROLLED STUDY; FEMALE; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MEDICAL RECORD; PREGNANCY; PROSPECTIVE STUDY; RECIPIENT; SCREENING TEST; THROMBOCYTE COUNT; THROMBOCYTOPENIA;

ANTIGENS, HUMAN PLATELET; AUTOANTIBODIES; BLOOD DONORS; CONFIDENCE INTERVALS; FEMALE; GENOTYPE; HOMOZYGOTE; HUMANS; SWITZERLAND;

EID: 0346505230     PISSN: 14664860     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.thj.6200338     Document Type: Article

References (17)

1. Schnaidt M, Wernet D. Platelet-specific antibodies in female blood donors after pregnancy. Transfus Med 2000; 10: 77-80.
2. Scott EP, Moilan-Bergeland J, Dalmasso AP. Posttransfusion thrombocytopenia associated with passive transfusion of a platelet-specific antibody. Transfusion 1988; 28: 73-76.
3. Warkentin TE, Smith JW, Hayward CP, Ali AM, Kelton JG. Thrombocytopenia caused by passive transfusion of anti-glycoprotein Ia/IIa alloantibody (anti-HPA-5b). Blood 1992; 79: 2480-2484.
4. Solenthaler M, Krauss JK, Boehlen F, Koller R, Hug M, Lammle B. Fatal fresh frozen plasma infusion containing HPA-1a alloantibodies. Br J Haematol 1999; 106: 258-259.
5. Kiefel V, Santoso S, Weisheit M, Mueller-Eckhardt C. Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet-reactive antibodies. Blood 1987; 70: 1722-1726.
6. de Moerloose P, Boehlen F, Extermann P, Hohlfeld P. Neonatal thrombocytopenia: incidence and characterization of maternal antiplatelet antibodies by MAIPA assay. Br J Haematol 1998; 100: 735-740.
7. Boehlen F, Kaplan C, de Moerloose P. Severe neonatal alloimmune thrombocytopenia due to anti-HPA-3a. Vox Sang 1998; 74: 201-204.
8. Kiefel V. The MAIPA assay and its application in immunohaematology. Transfus Med 1992; 2: 181-188.
9. Boehlen F, Bulla O, de Moerloose P. Evaluation of a new antigen capture ELISA for detection and characterization of platelet alloantibodies. Thromb Res 1998; 92: 27-32.
10. Simsek S, Faber NM, Bleeker PM, Vlekke AB, Huiskes E, Goldschmeding R et al. Determination of human platelet antigen frequencies in the Dutch population by immunophenotyping and DNA (allele-specific restriction enzyme) analysis. Blood 1993; 81: 835-840.
11. Holensteiner A, Walchshofer S, Adler A, Kittl EM, Mayr WR, Panzer S. Human platelet antigen gene frequencies in the Austrian population. Haemostasis 1995; 25: 133-136.
12. Merieux Y, Debost M, Bernaud J, Raffin A, Meyer F, Rigal D. Human platelet antigen frequencies of platelet donors in the French population determined by polymerase chain reaction with sequence-specific primers. Pathol Biol 1997; 45: 697-700.
13. Verran J, Grey D, Bennett J, Lown JA, Erber WN. HPA-1, 3, 5 genotyping to establish a typed platelet donor panel. Pathology 2000; 32: 89-93.
14. Ribera A, Parra R, Gallardo D, Perez P, Rodriguez J, Pujol M. Frequency of platelet antibodies against HPA-5b in Spanish pregnant women. Vox Sang 1994; 67(Suppl 2): 12.
15. Panzer S, Auerbach L, Cechova E, Fischer G, Holensteiner H, Kitl EM et al. Maternal alloimmunization against fetal platelet antigens: a prospective study. Br J Haematol 1995; 90: 655-660.
16. a. Vox Sang 1989; 57: 90-91.
17. Semana G, Zazoun T, Alizadeh M, Morel-Kopp MC, Genetet B, Kaplan C. Genetic susceptibility and anti-human platelet antigen 5b alloimmunization. Role of HLA class II and TAP genes. Human Immunol 1996; 46: 114-119.