Inside-out-application of ivermectin in the treatment of scabies - A hypothesis;Inside-out-applikation von ivermectin bei skabies - Eine hypothese

JDDG - Journal of the German Society of Dermatology

Volumn 1, Issue 12, 2003, Pages 933-937

  Haas, Norbert ^a   Frank, Kathrin ^a   Jacobi, Ute ^a   Katzung, Walter ^a   Sterry, Wolfram ^a   Lademann, Juergen ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; ESTROGEN; ISOTRETINOIN; IVERMECTIN; STEROID HORMONE; TERBINAFINE;

ABDOMEN; ADULT; AGED; ANDROGEN SYNTHESIS; AXILLA; DRUG ABSORPTION; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG INDICATION; DRUG PENETRATION; ELECTRON MICROSCOPY; EPIDERMIS; FEMALE; HUMAN; HYPOGONADISM; HYPOTHESIS; KERATINOCYTE; MALE; NONHUMAN; PARASITE; PEDICULOSIS; REVIEW; SCABIES; SEBUM SECRETION; STRATUM CORNEUM; THENAR;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; FEMALE; HUMANS; INSECTICIDES; IVERMECTIN; MALE; MIDDLE AGED; MITES; SCABIES; SKIN; TIME FACTORS;

EID: 0346504108     PISSN: 16100379     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (36)

1. Paasch U, Haustein UF. Behandlung der endemischen Skabies mit Allethrin, Permethrin und Ivermectin. Evaluation eines Behandlungskonzeptes. Hautarzt 2001; 52: 31-37.
2. Haas N, Henz BM, Ohlendorf D. Is a single oral dose of ivermectin sufficient in crusted scabies? Int J Dermatol 2001; 40: 599-600.
3. Chosidow O. Scabies and pediculosis. Lancet 2000; 355: 819-826.
4. Burkhart CN, Burkhart CG. Ivermectin: a few caveats are warranted before initiating therapy for scabies. Arch Dermatol 1999; 135: 1549-1550.
5. Meinking TL, Elgart GW. Scabies therapy for the millennium. Pediatr Dermatol 2000; 17: 154-156.
6. Chouela EN, Abeldano AM, Pellerano G, La Forgia M, Papale RM, Garsd A, Balian MC, Battista V, Poggio N. Equivalent therapeutic efficacy and safety of ivermectin and lindane in the treatment of human scabies. Arch Dermatol 1999; 135: 651-655.
7. Okonkwo PO, Ogbuokiri JE, Ofoegbu E, Klotz U. Protein binding and ivermectin estimations in patients with onchocerciasis. Clin Pharmacol Ther 1993; 53: 426-430.
8. Baraka OZ, Mahmoud BM, Marschke CK, Geary TG, Homeida MM, Williams JF. Ivermectin distribution in the plasma and tissues of patients infected with Onchocerca volvulus. Eur J Clin Pharmacol 1996; 50: 407-410.
9. Edwards G, Dingsdale A, Helsby N, Orme ML, Breckenridge AM. The relative systemic availability of ivermectin after administration as capsule, tablet, and oral solution. Eur J Clin Pharmacol 1988; 35: 681-684.
10. Wolff HH, Kock S. Ivermectin als orale Einmalbehandlung der Skabies. Deutsches Ärzteblatt 1998; 95: 1570-1572.
11. Ogbuokiri JE, Ozumba BC, Okonkwo PO. Ivermectin levels in human breastmilk. Eur J Clin Pharmacol 1993; 45: 389-390.
12. Tzenow I, Wehmeier M, Melnik B. Orale Behandlung der Scabies mit Ivermectin. Hautarzt 1997; 48: 2-4.
13. Folster Holst R, Rufli T, Christophers E. Die Skabiestherapie unter besonderer Berücksichtigung des frühen Kindesalters, der Schwangerschaft und Stillzeit. Hautarzt 2000; 51: 7-13.
14. Victoria J, Trujillo R. Topical ivermectin: a new successful treatment for scabies. Pediatr Dermatol 2001; 18: 63-65.
15. Lademann J, Katzung W, Lindemann U, Haas N, Frank K, Schaefer H, Sterry W. Drug delivery into the stratum corneum: inside out penetration. Perspectives in percutaneous penetration, Antibes-Juan-les-Pins: 2002.
16. Ließ HD, Lademan J, Leonhardt JWA. A new type of miniaturized drift sensor and its application. Proc. biomed optics Europe, Budapest: SPIE-Series, 1993.
17. Haas N, Lindemann U, Frank K, Sterry W, Lademann J, Katzung W. Rapid and preferential sebum secretion of ivermectin: a new factor that may determine drug responsiveness in patients with scabies. Arch Dermatol 2002; 138: 1618-1619.
18. Scott EW. The distribution and some pharmacokinetic parameters of ivermectin in pigs. Vet Res Commun 1992; 16: 139-146.
19. Walton SF, Myerscough MR, Currie BJ. Studies in vitro on the relative efficacy of current acaricides for Sarcoptes scabiei var. hominis. Trans R Soc Trop Med Hyg 2000; 94: 92-96.
20. Usha V, Gopalakrishnan Nair TV. A comparative study of oral ivermectin and topical permethrin cream in the treatment of scabies. J Am Acad Dermatol 2000; 42: 236-240.
21. Downs A. Comparing antiscabietic treatment. Arch Dermatol 1997; 133: 526.
22. Fimiani M, Mazzatenta C, Alessandrini C, Paccagnini E, Andreassi L. The behaviour of Sarcoptes scabiei var. hominis in human skin: an ultrastructural study. J Submicrosc Cytol Pathol 1997; 29: 105-113.
23. Heilesen B. Studies on Acarus scabiei and scabies. Acta Derm Venereol (Stockh) 1946; 26, Suppl. 14: 1-370.
24. Macotela Ruiz E, Pena Gonzalez G. The treatment of scabies with oral ivermectin. Gac Med Mex 1993; 129: 201-205.
25. Elmogy M, Fayed H, Marzok H, Rashad A. Oral ivermectin in the treatment of scabies. Int J Dermatol 1999; 38:926-928.
26. Birnbaum JE. Pharmacology of the allylamines. J Am Acad Dermatol 1990; 23: 782-785.
27. Mumcuoglu KY, Miller J, Rosen LJ, Galun R. Systemic activity of ivermectin on the human body louse (Anoplura: Pediculidae). J Med Entomol 1990;27:72-75.
28. Brimer L, Bonlokke L, Pontoppidan C, Henriksen SA, Gyrd Hansen N, Rasmussen F. A method for in vitro determination of the acaricidal effect of ivermectin using Sarcoptes scabiei var. suis as test organism. Vet Parasitol 1995; 59: 249-255.
29. Meinking TL, Taplin D, Hermida JL, Pardo R, Kerdel FA. The treatment of scabies with ivermectin. N Engl J Med 1995; 333: 26-30.
30. Hegazy AA, Darwish NM, Abdel Hamid IA, Hammad SM. Epidemiology and control of scabies in an Egyptian village. Int J Dermatol 1999; 38: 291-295.
31. Dannaoui E, Kiazand A, Piens M, Picot S. Use of ivermectin for the management of scabies in a nursing home. Eur J Dermatol 1999; 9: 443-445.
32. Merck HF, Bickers DR: Dermatopharmakologie und Dermatotherapie, Blackwell, Berlin, 1992.
33. Goodfellow A, Alaghband Zadeh J, Carter G, Cream JJ, Holland S, Scully J, Wise P. Oral spironolactone improves acne vulgaris and reduces sebum excretion. Br J Dermatol 1984; 111: 209-214.
34. del Giudice P, Marty P, Gari Toussaint M, Le Fichoux Y. Ivermectin in elderly patients. Arch Dermatol 1999; 135:351-352.
35. Kohn FM, Ring J, Schill WB. Dermatologic aspects of male hypogonadism. Hautarzt 2000; 51: 223-230.
36. Cestari SC, Petri V, Rotta O, Alchorne MM. Oral treatment of crusted scabies with ivermectin: report of two cases. Pediatr Dermatol 2000; 17: 410-414.