Ulceration of psoriatic plaques - Cutaneous adverse effects of high dose methotrexate in psoriasis: A report of three cases;Ulceração das placas psoriáticas - Efeito cutâneo adverso do metotrexato em altas doses no tratamento da psoríase: Relato de três casos

Anais Brasileiros de Dermatologia

Volumn 78, Issue 6, 2003, Pages 749-753

  De Torre Ataíde, Deborah Skusa ^c   Kucharski Esmanhoto, Luciana Dorigo ^a   Helmer, Karin Adriane ^a   Caron Guerra, Ivette Renata ^b   De Campos Graf Guimarães, Christine ^b   Moritz, Sandra ^a,b  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b Brazilian Society of Dermatology/AMB   (Brazil)

^c NONE

Author keywords

Methotrexate adverse effects; Psoriasis

Indexed keywords

METHOTREXATE;

ACUTE TOXICITY; ADULT; AGED; ANEMIA; ANOREXIA; ARTICLE; BLISTER; BLOOD TOXICITY; BONE MARROW SUPPRESSION; CASE REPORT; DNA SYNTHESIS INHIBITION; DRUG EFFECT; GLOMERULUS FILTRATION RATE; HUMAN; HYPOXIA; KIDNEY FUNCTION; LEUKOPENIA; LIVER TOXICITY; MALE; MEGALOBLASTIC ANEMIA; MEGALOCYTOSIS; NAUSEA; PHOTOSENSITIVITY DISORDER; PSORIASIS; SIDE EFFECT; SKIN NECROSIS; SKIN ULCER; THROMBOCYTOPENIA; TOXIC EPIDERMAL NECROLYSIS; URTICARIA; VASCULITIS; VOMITING;

EID: 0346503245     PISSN: 03650596     EISSN: None     Source Type: Journal    
DOI: 10.1590/s0365-05962003000600011     Document Type: Article

References (9)

1. Roenigk HH, Auerbach R, Mainbach H et al. Metotrexate in psoriasis: Consensus conference. J AM Acad Dermatol 1998;38(3):478-485.
2. Lopez AA, Toxicidad aguda por metotrexate en psoriasis. Gac Méd Méx 1999;135(5):513-516.
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4. Wallace CA, Sherry DD. A Practical Approach to Avoidance of Methotrexate Toxicity. J Rheumatol 1995;22(6):1009-1012.
5. Arruda LHF, Campbell GAM e Takahashi MDF. Psoriase. Anais Brasileiros de Dermatologia 2001;36(2):141-165.
6. Monterto LC, Gomez RS, Quirós JFB. Cutaneous Ulcerations in a Patient with Rheumatoid Arthrits Receiving Treatment with Methotrexate. J Rheumatol 2000;27(9)2290-2291.
7. Callen JP, Kulp-Shorten CL. Methotrexate. In: Wolkerton SE, Wilkin JK. Systemic Drugs for Skin Diseases. WB Sounders Company, 1991:152-66.
8. Procter PR. Methotrexate-induced skin necrosis in psoriasis. S Afr Méd J. 1987;72(12):888.
9. Van Dooren-Greebe RJ, Kuijpers ALA, Mulder J et al. Methotrexate revisited: effects of long-term treatment in psoriasis. Brit J Dermatol 1994;130:204-210.