NFAT transcription factors control HIV-1 expression through a binding site downstream of TAR region

Immunobiology

Volumn 208, Issue 4, 2003, Pages 361-365

  Romanchikova, Nadezhda ^a,b   Ivanova, Victorija ^b   Scheller, Carsten ^a   Jankevics, Eriks ^b   Jassoy, Christian ^a   Serfling, Edgar ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF LATVIA   (Latvia)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR NFAT;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; GENE EXPRESSION; GENE INDUCTION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOGENESIS; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TRANSACTIVATION; VIRUS TRANSCRIPTION;

EID: 0346496202     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1078/0171-2985-00283     Document Type: Article

References (11)

1. Alcami J, Lain de Lera T, Folgueira L, Pedraza MA, Jacque JM, Bachelerie F, Noriega AR, Hay RT, Harrich D and Gaynor RB. 1995. Absolute dependence on kappa B responsive elements for initiation and Tat-mediated amplification of HIV transcription in blood CD4 T lymphocytes. EMBO J. 14: 1552-1560.
2. Chen BK, Feinberg MB and Baltimore D. 1997. The kappa B sites in the human immunodeficiency virus type 1 long terminal repeat enhance virus replication yet are not absolutely required for viral growth. J. Virol. 71: 5495-5504.
3. Chuvpilo S, Zimmer M, Kerstan A, Glöckner J, Avots A, Escher C, Fischer C, Inashkina I, Jankevics E, Berberich-Siebelt F, Schmitt E and Serfling E.1999. Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells. Immunity 10: 261-269.
4. Cron RQ, Bartz SR, Clausell A, Bort SJ, Klebanoff SJ and Lewis DB. 2000. NFAT1 enhances HIV-1 gene expression in primary human CD4 T cells. Clin. Immunol. 94: 179-191.
5. Kinoshita S, Su L, Amano M, Timmerman LA, Kaneshima H and Nolan GP. 1997. The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. Immunity 6: 235-244.
6. Kinoshita S, Chen BK, Kaneshima H and Nolan GP 1998. Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells. Cell 95: 595-604.
7. Macian F and Rao A. 1999. Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1. Mol. Cell. Biol. 19: 3645-3653.
8. Northrop JP, Ho SN, Chen L, Thomas DJ, Timmerman LA, Nolan GP, Admon A and Crabtree GR. 1994. NF-AT components define a family of transcription factors targeted in T-cell activation. Nature 369: 497-502.
9. Pereira LA, Bentley K, Peeters A, Churchill MJ and Deacon NJ. 2000. A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter. Nucleic Acids Res. 28: 663-668.
10. Randak C, Brabletz T, Hergenröther M, Sobotta I and Serfling E. 1990. Cyclosporin A suppresses the expression of the interleukin 2 gene by inhibiting the binding of lymphocyte-specific factors to the IL-2 enhancer. EMBO J. 9: 2529-2536.
11. Schreiber E, Matthias P, Müller MM and Schaffner W. 1989. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res. 17: 6419.