Effects of hypoxia on the proliferation and differentiation of CD34+ hematopoietic stem/progenitor cells and their response to cytokines

Acta Physiologica Sinica

Volumn 52, Issue 2, 2000, Pages 143-146

  Sun, Bing ^a   Bai, Ci Xian ^a   Feng, Kai ^a   Li, Liang ^a   Zhao, Peng ^a   Pei, Xue Tao ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

BFU E; CD34+ cells; Hypoxia; Mononucleated cells

Indexed keywords

CD34 ANTIGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3;

ARTICLE; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CELL HYPOXIA; CYTOLOGY; FETUS BLOOD; HEMATOPOIETIC STEM CELL; HUMAN; MONONUCLEAR CELL;

ANTIGENS, CD34; CELL DIVISION; CELL HYPOXIA; CELLS, CULTURED; FETAL BLOOD; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-3; LEUKOCYTES, MONONUCLEAR;

EID: 0346480840     PISSN: 03710874     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. + hematopoietic progenitor cells. Chin J Hematol, 1998, 19: 289-293 (in Chinese with English abstract) .
2. Smith S, Broxmeyer HE. The influence of oxygen tension on the long-term growth in vitro of hematopoietic progenitor cells from human cord blood. Br J Haematol, 1986, 63: 29-33.
3. Koller MR, Bender JG, Papoutsakis ET et al. Effects of synergistic cytokine combination, low oxygen, and irradiated stroma on the expansion of human cord blood progenitors. Blood, 1992, 80: 403-409.
4. Beitner-Johnson D, Shull GE, Dedman JR et al. Regulation of gene expression by hypoxia: A molecular approach. Respir Physiol, 1997, 110: 87-97.
5. Schibler KR, Li Y, Ohls RK et al. Possible mechanisms accounting for the growth factor independence of hematopoietic progenitors from umbilical cord blood. Blood, 1994, 84: 3679-3684.
6. De Wolf JTM, Muller EW, Hendriks DH et al. Mast cell growth factor modulates CD36 antigen expression on eythroid progenitors from human bone marrow and peripheral blood associated with ongoing differentiation. Blood, 1994, 84: 59 -64.
7. Cipolleschi MG, D'Ippolito G, Bernabei PA et al. Severe hypoxia enhances the formation of erythroid bursts human cord blood cells and the maintenance of BFU-E in vitro. Exp Hematol, 1997, 25: 1187-1194.